Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New blood test tracks neurodegenerative changes specifically in Alzheimer's disease

A new blood test that can track and follow the neurodegeneration in Alzheimer's disease - and exclude other dementias.

16 Jan 2023

Study identifies new tau regulators as viable therapeutic targets for Alzheimer's and other tauopathies

Neurodegenerative diseases affect millions of people worldwide and as our life expectancy increases, more individuals are expected to be affected in the coming decades.

16 Jan 2023

Walking pace and handgrip strength can indicate dementia risk

The current study, published in the journal Alzheimer's Research & Therapy, drew data on almost 496,000 participants from the UK Biobank Study. None had symptoms or a diagnosis of dementia at the start of the study.

15 Jan 2023

A 35% increase in physical activity improves memory and cognition in healthy elderly

A randomized controlled trial conducted on elderly individuals shows that an improvement in physical fitness and cognition can be achieved by increasing daily physical activity to a certain level. The trial findings are published in the journal Alzheimer's Research & Therapy.

15 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

Risks and benefits of recently approved Alzheimer’s drug

The U.S. Food and Drug Administration (FDA) recently granted approval to Lecanemab, the first Alzheimer's disease treatment to win approval since the largely failed rollout of Aduhelm two years ago.

13 Jan 2023

Ending involuntary commitments would shift burden of dementia care to strapped communities

State lawmakers from both parties have shown support for a plan to stop the practice of committing people with Alzheimer's disease, other types of dementia, or traumatic brain injuries without their consent to the troubled Montana State Hospital and instead direct them to treatment in their communities.

13 Jan 2023

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

A growing pile of evidence indicates that the tens of trillions of microbes that normally live in our intestines - the so-called gut microbiome - have far-reaching effects on how our bodies function.

12 Jan 2023

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

The Alzheimer's Drug Discovery Foundation and Harrington Discovery Institute at University Hospitals in Cleveland have granted an ADDF-Harrington Scholar Award to Christiane Wrann, PhD, DVM, Associate Professor in Medicine at the Cardiovascular Research Center and the McCance Center for Brain Health at Massachusetts General Hospital and the Harvard Medical School in Boston.

12 Jan 2023

The same genetic factors may contribute to both cardiometabolic diseases and dementia

Being affected by several cardiometabolic diseases such as diabetes, heart disease and stroke, is linked to a greatly increased risk of dementia and Alzheimer's disease.

12 Jan 2023

Blood-based markers could lead to earlier detection of Alzheimer's disease

Alzheimer's disease begins decades before any symptoms, such as memory loss, start to show. Consequently, early diagnosis increases the chances of slowing the disease down with drugs.

10 Jan 2023

Protein Medin: A new treatment target for Alzheimer's

A recent study published in the journal Nature reported the co-aggregation of medin, a fragment of lactadherin, with vascular amyloid-β in Alzheimer’s disease (AD).

10 Jan 2023

Neural networks responsible for spatial perception change in a nonlinear manner, study shows

Young children sometimes believe that the moon is following them, or that they can reach out and touch it. It appears to be much closer than is proportional to its true distance.

5 Jan 2023

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Numerous studies have shown health benefits of time-restricted eating including increase in life span in laboratory studies, making practices like intermittent fasting a hot topic in the wellness industry.

3 Jan 2023

Salk scientists show how a microprotein can increase appetite in mice

Obesity and metabolic diseases, such as diabetes, are extremely common in the United States. Tiny proteins called microproteins have long been overlooked in research, but new evidence demonstrates that they have an important role in metabolism.

3 Jan 2023

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers."

3 Jan 2023

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

A group of neuroscientists led by a University of Pittsburgh School of Medicine researcher developed a test to detect a novel marker of Alzheimer's disease neurodegeneration in a blood sample. A study on their results was published today in Brain.

28 Dec 2022

Targeting defective tau proteins may be needed to treat Alzheimer’s patients

In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to be able to affect the course of this relentless, incurable disease.

26 Dec 2022

Breached dolphin's brains show neuropathology similar to Alzheimer's

In a new European Journal of Neuroscience study, scientists studied the brains of Odontocetes (Toothed whales) to document the presence or absence of neuropathological hallmarks of AD.

25 Dec 2022

DISCO-MS technology enables the study of diseases at their earliest stages

How can you trace a single diseased cell in an intact brain or a human heart? The search resembles looking for a needle in a haystack.

22 Dec 2022

Alzheimer's Disease News and Research

Further Reading

New blood test tracks neurodegenerative changes specifically in Alzheimer's disease

Study identifies new tau regulators as viable therapeutic targets for Alzheimer's and other tauopathies

Walking pace and handgrip strength can indicate dementia risk

A 35% increase in physical activity improves memory and cognition in healthy elderly

Valuable tool reveals the connections between gut microbes and the brain

Risks and benefits of recently approved Alzheimer’s drug

Ending involuntary commitments would shift burden of dementia care to strapped communities

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

The same genetic factors may contribute to both cardiometabolic diseases and dementia

Blood-based markers could lead to earlier detection of Alzheimer's disease

Protein Medin: A new treatment target for Alzheimer's

Neural networks responsible for spatial perception change in a nonlinear manner, study shows

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Salk scientists show how a microprotein can increase appetite in mice

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

Targeting defective tau proteins may be needed to treat Alzheimer’s patients

Breached dolphin's brains show neuropathology similar to Alzheimer's

DISCO-MS technology enables the study of diseases at their earliest stages

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