Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Does a second monovalent SARS-CoV-2 mRNA booster increase neutralizing activity to Omicron variants in nursing home residents and healthcare workers?

Researchers investigated whether the second booster dose of monovalent COVID-19 mRNA vaccines increases antibody titers and neutralization potential against the SARS-CoV-2 Omicron VOC among NH residents and HCWs.

30 Jan 2023

Study evaluates SARS-CoV-2-specific antibody response in human milk

In a recent study published in the journal Communications Biology, researchers investigated the effect of the coronavirus disease 2019 (COVID-19) vaccine booster on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies in the milk of lactating women. Additionally, they explored whether the booster-induced antibody response differed from the homologous and heterologous boosting schedule of their primary vaccination.

29 Jan 2023

Pregnancy has no effect on long-term immune response to SARS-CoV-2 mRNA vaccination

The immunologic milieu of pregnancy has no effect on the durability of the anti-S IgG response to COVID-19 vaccination

29 Jan 2023

Doctoral research presents predictive value of biomarkers for inflammatory bowel diseases

Under the supervision of four professors from the UMCG departments of Gastroenterology and Hepatology and Pathology and Medical Biology, Bourgonje conducted doctoral research on the predictive value of biomarkers for inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis.

29 Jan 2023

Activated neutrophils can become potent cancer fighters

Elevated levels of immune cells, called neutrophils, in tumors have been associated with poor outcomes in people with cancer.

27 Jan 2023

Protein adduction and p53 tumor suppressor inhibition

Researchers assessed the impact of protein adduction on p53 tumor suppressor inhibition.

27 Jan 2023

Pancreatic cancer study reveals the cause of tumor cell resistance to immunotherapy

A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.

26 Jan 2023

Researchers discover the impact of microRNA on inflammation in lupus

A group of researchers from the Graduate School of Medicine at Nagoya University in Japan have discovered the impact of microRNA (miRNA) on inflammation in lupus in mice.

26 Jan 2023

Atomic-level computer model of the H1N1 virus reveals new vulnerabilities

According to the World Health Organization, each year there are an estimated 1 billion cases of influenza, between 3-5 million severe cases and up to 650,000 influenza-related respiratory deaths globally.

25 Jan 2023

Pembrolizumab offers major added survival benefit for patients with advanced cervical cancer

Pembrolizumab has recently been approved in combination with chemotherapy for the treatment of women with persistent, recurrent, or metastatic cervical cancer whose tumors express PD-L1. Chemotherapy with or without bevacizumab is possible.

25 Jan 2023

Breathing and tilting motions of influenza glycoproteins could be exploited to better defend against flu

The potential "tripledemic" of influenza, SARS-CoV-2 and RSV (respiratory syncytial virus) infection continues to be a concern.

25 Jan 2023

FDA briefing discusses different COVID-19 vaccination regimens

In a recent briefing document published by the United States Food and Drug Administration (US-FDA) ahead of an advisory committee meeting scheduled for January 26, 2023, the national agency proposed that people should be given yearly coronavirus disease 2019 (COVID-19) vaccines.

25 Jan 2023

Data demonstrates SARS-CoV-2 Omicron XBB.1.5 substantially escapes NAb responses after bivalent mRNA boosting

Researchers reported that the SARS-CoV-2 Omicron XBB.1.5 variant evades neutralizing response elicited by bivalent vaccine boosters.

25 Jan 2023

Maternal and perinatal outcomes of women infected with SARS-CoV-2 during the Omicron wave in Italy

Researchers assessed the impact of SARS-CoV-2 vaccination on pregnant women during the Omicron wave.

25 Jan 2023

Researchers discover the gene responsible for radiation resistance in mutant IDH1 glioma

It's a good news, bad news story. Patients whose brain tumors have a mutated enzyme called IDH1 typically live longer than those without the mutation.

24 Jan 2023

Researchers identify potent pan-sarbecovirus antibodies from non-human primates vaccinated with an AS03 adjuvanted subunit SARS-CoV-2 vaccine

Researchers assessed the effectiveness of pan-sarbecovirus-neutralizing antibodies against SARS-CoV-2.

24 Jan 2023

Researchers report a reduction in hospitalizations and deaths from SARS-CoV-2 infections during the Omicron variant-dominated wave in Malawi

Researchers conducted a serosurvey during the SARS-CoV-2 Omicron wave in Malawi.

23 Jan 2023

Study reviews mechanistic data on new methods of allergy prevention and treatment

In a recent article published in Science Translational Medicine, researchers reviewed the cause and the underlying pathophysiology of allergic diseases.

23 Jan 2023

Bivalent BA.4-5 or BA.1 mRNA-booster given as a fourth dose associated with increased protection against COVID-19 hospitalization and death

Researchers compared the efficiency of the SARS-CoV-2 Omicron BA.4-5 and BA.1 bivalent mRNA-booster vaccines.

23 Jan 2023

Genetic disorder that causes immunodeficiency and susceptibility to opportunistic infections discovered

An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia.

23 Jan 2023

Antibody News and Research

Further Reading

Does a second monovalent SARS-CoV-2 mRNA booster increase neutralizing activity to Omicron variants in nursing home residents and healthcare workers?

Study evaluates SARS-CoV-2-specific antibody response in human milk

Pregnancy has no effect on long-term immune response to SARS-CoV-2 mRNA vaccination

Doctoral research presents predictive value of biomarkers for inflammatory bowel diseases

Activated neutrophils can become potent cancer fighters

Protein adduction and p53 tumor suppressor inhibition

Pancreatic cancer study reveals the cause of tumor cell resistance to immunotherapy

Researchers discover the impact of microRNA on inflammation in lupus

Atomic-level computer model of the H1N1 virus reveals new vulnerabilities

Pembrolizumab offers major added survival benefit for patients with advanced cervical cancer

Breathing and tilting motions of influenza glycoproteins could be exploited to better defend against flu

FDA briefing discusses different COVID-19 vaccination regimens

Data demonstrates SARS-CoV-2 Omicron XBB.1.5 substantially escapes NAb responses after bivalent mRNA boosting

Maternal and perinatal outcomes of women infected with SARS-CoV-2 during the Omicron wave in Italy

Researchers discover the gene responsible for radiation resistance in mutant IDH1 glioma

Researchers identify potent pan-sarbecovirus antibodies from non-human primates vaccinated with an AS03 adjuvanted subunit SARS-CoV-2 vaccine

Researchers report a reduction in hospitalizations and deaths from SARS-CoV-2 infections during the Omicron variant-dominated wave in Malawi

Study reviews mechanistic data on new methods of allergy prevention and treatment

Bivalent BA.4-5 or BA.1 mRNA-booster given as a fourth dose associated with increased protection against COVID-19 hospitalization and death

Genetic disorder that causes immunodeficiency and susceptibility to opportunistic infections discovered

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