Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Study identifies a urinary biomarker to reveal early-stage Alzheimer’s disease

Could a simple urine test reveal if someone has early-stage Alzheimer’s disease and could this pave the way for large-scale screening programs? A new study in Frontiers in Aging Neuroscience certainly suggests so. The researchers tested a large group of patients with Alzheimer’s disease of different levels of severity and healthy controls with normal cognition to identify differences in urinary biomarkers.

30 Nov 2022

Simultaneous radiation and immunotherapy can benefit mNSCLC patients with high tumor aneuploidy

In many cancer types, cancer cells try to survive by escaping attack from the immune system. These cancer cells hijack mechanisms called immune checkpoints to trick the immune system into thinking they are healthy cells.

28 Nov 2022

Researchers uncovers a link between D-amino acids and severe viral infection

Just as bricks are key components in constructing a building, molecules known as amino acids are essential components in constructing proteins in the body.

28 Nov 2022

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Researchers used cellular cryo-electron tomography (cryo-ET) to demonstrate the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in coronavirus disease 2019 (COVID-19)-triggered severe coagulopathies.

28 Nov 2022

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

Addressing this gap in research, a recent Nature Medicine study hypothesized that 4R isoform-specific MTBR-tau species accumulate in the patient’s brain of specific subtypes of 4R tauopathies.

28 Nov 2022

Glycan signatures in rheumatic diseases and their associated functional implications

A new paper examines the understanding of glycosylation in an array of rheumatic diseases and indicates the potential for therapeutic interventions using the same mechanism.

28 Nov 2022

Study reveals a wide variation in the water needs of people around the globe

A new study of thousands of people reveals a wide range in the amount of water people consume around the globe and over their lifespans, definitively spilling the oft-repeated idea that eight, 8-ounce glasses meet the human body's daily needs.

25 Nov 2022

New biomarker can help identify people with a primary tauopathy

Zooming in on a single disease and studying it intensely is often the most productive route to finding treatments. But there's no easy way to distinguish among people living with any of the primary tauopathies - a group of rare brain diseases marked by rapidly worsening problems with thinking and movement - because the symptoms are too similar.

24 Nov 2022

New study points to a strategy for inhibiting hyper-progression of melanoma

Duke Cancer Institute researchers have identified potential biomarkers that predict the likelihood for checkpoint inhibitor drugs to backfire, driving hyper-progression of melanoma cells instead of unleashing the immune system to fight them.

23 Nov 2022

MiRNAs can be used as a biomarker to predict disease recurrence and mortality in breast cancer patients

Researchers at University of Galway have determined that biomarkers known as microRNAs can help predict which patients with breast cancer are likely to face a recurrence of the disease and death.

23 Nov 2022

Proteomic analysis identifies novel phenotypes associated with COVID-19 severity in circulating immune cells

In a recent study, researchers used proteomic analysis to identify novel immune cell phenotypes associated with severe coronavirus disease 2019 (COVID-19).

22 Nov 2022

The vaginal microbiome through the lens of systems biology

A new paper recently published online in Trends in Microbiology journal reviews the systems biology approach to explore the vaginal microbiome (VMB), helping to understand its composition and function and the mechanisms by which it interacts with the host.

22 Nov 2022

Time-restricted eating may benefit Alzheimer's

In a recent study published in the Experimental Gerontology journal, researchers in the United States assessed the impact of time-restricted eating (TRE) on Alzheimer's disease (AD), cognitive decline, and sleep.

21 Nov 2022

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

A Ludwig Cancer Research study has revealed a single protein expressed at high levels by cancer cells across a broad range of malignancies that erects a multifaceted barrier to anti-cancer immune responses in mouse models of cancer and so shields tumors from immune detection and destruction.

20 Nov 2022

Wearable activity tracker data can be used to obtain metrics associated with user's physical health

A new Johns Hopkins study shows that data gathered from wearable activity trackers can be used to obtain several metrics associated with the user's general physical health and cardiovascular health status.

20 Nov 2022

Experts investigate the role of IL-26 in COVID-19

Researchers at Karolinska Institutet in Sweden have shown that patients with acute COVID-19 infection have increased levels of the cytokine IL-26 in their blood. Moreover, high IL-26 levels correlate with an exaggerated inflammatory response that signifies severe cases of the disease. The findings, which are presented in Frontiers in Immunology, indicate that IL-26 is a potential biomarker for severe COVID-19.

17 Nov 2022

Biomarker News and Research

Further Reading

Study identifies a urinary biomarker to reveal early-stage Alzheimer’s disease

Simultaneous radiation and immunotherapy can benefit mNSCLC patients with high tumor aneuploidy

Researchers uncovers a link between D-amino acids and severe viral infection

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

Glycan signatures in rheumatic diseases and their associated functional implications

Study reveals a wide variation in the water needs of people around the globe

New biomarker can help identify people with a primary tauopathy

New study points to a strategy for inhibiting hyper-progression of melanoma

MiRNAs can be used as a biomarker to predict disease recurrence and mortality in breast cancer patients

Proteomic analysis identifies novel phenotypes associated with COVID-19 severity in circulating immune cells

The vaginal microbiome through the lens of systems biology

Time-restricted eating may benefit Alzheimer's

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

Wearable activity tracker data can be used to obtain metrics associated with user's physical health

Experts investigate the role of IL-26 in COVID-19

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

Researchers identify 35 genes that are highly expressed in patients with long-term Lyme disease

Ketogenic diet may show more promising results than Mediterranean diets in short-term type 2 diabetes management

New discovery reveals which patients will survive longer after receiving immunotherapy

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo