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Scientists discover novel species of betapolyomavirus in Kenya

A new study published as a pre-proof in the journal Virologica Sinica, is follow-up research to a previous study on the discovery of novel rodent viruses of various RNA viral families in Kenya.

12 Jun 2022

Study investigates SARS-CoV-2 escape from nirmatrelvir

Researchers assessed SARS-CoV-2 Alpha, Delta, and Omicron variants’ resistance to nirmatrelvir, a protease inhibitor of SARS-CoV-2.

10 Jun 2022

Efficacy of BNT162b2 vaccine against SARS-CoV-2 Omicron sublineages and Deltacron

In a recent study posted to the bioRxiv* pre-print server, researchers at the University of Texas Medical Branch, Pfizer Vaccines Research & Development and BioNTech assessed the neutralization titers of sera from individuals vaccinated with the BNT162b2 coronavirus disease 2019 (COVID-19) vaccine and previously infected with the Omicron sublineage BA.1.

10 Jun 2022

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

A drug used to target IDH1 mutations in select cancers also appears to inhibit the wild-type form of the enzyme, under certain conditions.

9 Jun 2022

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Researchers have discovered that infiltrating gliomas, a common brain and spinal cord tumor, are shaped by their genetic evolution and microenvironment, a finding that could lead to more targeted treatments.

9 Jun 2022

Researchers create first comprehensive functional map of genes expressed in human cells

The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including Whitehead Institute, and was finally completed in 2003.

9 Jun 2022

New electrical test to screen individuals at risk of sudden cardiac arrest

New research from the Victor Chang Cardiac Research Institute will allow families around the world to discover if they are carrying genetic mutations that cause sudden cardiac arrest – a condition that kills nine out of 10 victims.

9 Jun 2022

New disease that affects the macula discovered

Researchers from the National Eye Institute have identified a new disease that affects the macula, a small part of the light-sensing retina needed for sharp, central vision.

9 Jun 2022

Insights on the T cell epitope landscape for the five main SARS-CoV-2 variants of concern

Researchers generated an AI resource to characterize the T cell epitope landscape for SARS-CoV-2 variants of concern.

9 Jun 2022

Most synonymous genetic mutations are strongly harmful, study shows

In the early 1960s, University of Michigan alumnus Marshall Nirenberg and a few other scientists deciphered the genetic code of life, determining the rules by which information in DNA molecules is translated into proteins, the working parts of living cells.

8 Jun 2022

SARS-CoV-2 is a generalist virus, infecting and evolving in numerous mammals and humans

In a recent article published in the bioRxiv* preprint server, researchers illustrated zooanthroponotic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and viral mutations specific to hosts.

8 Jun 2022

Where did Omicron's unique spike gene insertion originate?

In a recent study posted to the medRxiv* pre-print server, scientists at nference Labs investigated the origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) new variant of concern (VOC) Omicron's unique spike (S) gene insertion ins214EPE.

8 Jun 2022

Gastrointestinal complications caused by SARS-CoV-2

scientists discuss the gastrointestinal complications associated with COVID-19.

7 Jun 2022

How do viruses evolve to infect new hosts?

Researchers discuss how protein thermostability prevents the misfolding of viral proteins from being heated.

7 Jun 2022

Scientists provide crucial insights into the roles of inflammation and oxidative stress in certain cancers

Rampant inflammation has long been linked to cancer but exactly how it pushes healthy cells to transform into malignant ones has remained a mystery.

7 Jun 2022

Study reveals how common drug-resistant superbug responds to ‘last resort’ antibiotic

A study published today in Cell Reports reveals how populations of a bacterium called Pseudomonas respond to being treated with Colistin, a 'last resort' antibiotic for patients who have developed multi-drug resistant infections.

7 Jun 2022

The effect of Omicron breakthrough infection on the magnitude and breadth of serum neutralizing activity and memory B cells among BNT162b2 vaccinees

Researchers evaluated the impact of breakthrough infections with SARS-CoV-2 Omicron BA.1 sublineage on SARS-CoV-2 variants of concern neutralization and memory B lymphocytes formation among BNT162b2 vaccinees.

7 Jun 2022

Study offers recommendations for improving statistical inference in population genomics

The second century Alexandrian astronomer and mathematician Claudius Ptolemy had a grand ambition. Hoping to make sense of the motion of stars and the paths of planets, he published a magisterial treatise on the subject, known as the Almagest.

6 Jun 2022

Researchers evaluate how hundreds of different mutations impact key function of breast cancer gene

Inherited mutations in the BRCA1 gene can significantly increase a person's risk of breast and ovarian cancer - but not every mutation in the gene is harmful.

3 Jun 2022

Study: Nearly 43% of patients with KRAS-mutated lung cancer respond to experimental drug adagrasib

Nearly 43% of patients with non-small cell lung cancer (NSCLC) whose lung cancers harbored a specific KRAS mutation responded to the experimental drug adagrasib, and the targeted agent also showed activity against lesions in the brain that metastasized from the lung tumors, according to results of a study led by Dana-Farber Cancer Institute investigators.

3 Jun 2022

Mutation News and Research

Scientists discover novel species of betapolyomavirus in Kenya

Study investigates SARS-CoV-2 escape from nirmatrelvir

Efficacy of BNT162b2 vaccine against SARS-CoV-2 Omicron sublineages and Deltacron

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Researchers create first comprehensive functional map of genes expressed in human cells

New electrical test to screen individuals at risk of sudden cardiac arrest

New disease that affects the macula discovered

Insights on the T cell epitope landscape for the five main SARS-CoV-2 variants of concern

Most synonymous genetic mutations are strongly harmful, study shows

SARS-CoV-2 is a generalist virus, infecting and evolving in numerous mammals and humans

Where did Omicron's unique spike gene insertion originate?

Gastrointestinal complications caused by SARS-CoV-2

How do viruses evolve to infect new hosts?

Scientists provide crucial insights into the roles of inflammation and oxidative stress in certain cancers

Study reveals how common drug-resistant superbug responds to ‘last resort’ antibiotic

The effect of Omicron breakthrough infection on the magnitude and breadth of serum neutralizing activity and memory B cells among BNT162b2 vaccinees

Study offers recommendations for improving statistical inference in population genomics

Researchers evaluate how hundreds of different mutations impact key function of breast cancer gene

Study: Nearly 43% of patients with KRAS-mutated lung cancer respond to experimental drug adagrasib

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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