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New implantable biotechnology produces and releases CAR-T cells for attacking tumors

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed an implantable biotechnology that produces and releases CAR-T cells for attacking cancerous tumors.

24 Mar 2022

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

A recent study demonstrated that RNA interference could prophylactically protect against SARS-CoV-2.

24 Mar 2022

New device based on concert hall acoustics enables noninvasive, ultrasound brain treatments

A team led by engineers at the University of California San Diego has developed a device that is a first step to enabling noninvasive, ultrasound-based therapies for the brain.

23 Mar 2022

Monoclonal antibodies found to prevent lung inflammation in SARS-CoV-2-Omicron-infected mice

Researchers investigated how monoclonal antibodies, S309 and AZD7442, reduced lung infection in mice infected with the SARS-CoV-2 new variant of concern Omicron's BA.1, BA.1.1, and BA.2 sublineages.

23 Mar 2022

Novel monoclonal antibody found to have substantial neutralizing capacity against SARS-CoV-2 Omicron variant

Researchers reported a new monoclonal antibody, P2G3, which significantly neutralized the SARS-CoV-2 Omicron variant.

23 Mar 2022

Quantum dots can quantify specific types of cells inside deep tissues of the body

To accurately diagnose and treat diseases, doctors and researchers need to see inside bodies. Medical imaging tools have come a long way since the humble x-ray, but most existing tools remain too coarse to quantify numbers or specific types of cells inside deep tissues of the body.

23 Mar 2022

Novel optobiological system may shine light on protein aggregation in Parkinson's disease

A novel system to control protein aggregation in a model of Parkinson's disease may answer longstanding questions about how the disease begins and spreads, according to a new study published March 9th in the open-access journal PLOS Biology by Abid Oueslati of Laval University, Quebec, Canada, and colleagues.

23 Mar 2022

BGI discovery could pave the way for advances in organ regeneration and synthetic biology

In a world-first, scientists from BGI-Research, Chinese Academy of Sciences, and a group of partners published a study in Nature, announcing the discovery of a transgene-free, rapid, and controllable method to convert pluripotent stem-cells into bona fide 8-cell totipotent embryo-like cells, paving the way for advances in organ regeneration and synthetic biology.

22 Mar 2022

The obstacles to developing high-throughput 3D wound healing models

In this interview, News-Medical talks to Dr. Glauco Souza and Linda Boekestijn about their work in the wound healing space and how they devised a new high throughput 3D model for would healing.

From PromoCell 22 Mar 2022

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

In a new study, researchers aimed to determine if peptidyl-arginine deiminases inhibitors may be used as a novel class of host-targeting antivirals against human coronaviruses.

21 Mar 2022

How does the non-structural protein 1 affect COVID-19 pathogenicity?

Researchers discuss the effects of the SARS-CoV-2 non-structural protein 1 (Nsp1), which binds to the ribosomal subunit thus inhibiting translation.

20 Mar 2022

New virus-based approach for measuring variations in gene regulatory elements

Tohoku University scientists in Japan have developed a virus-based approach for measuring variations in gene regulatory elements, called transcription factors, as conditions change in live organisms.

18 Mar 2022

Innate and adaptive immune responses to BNT162b2 vaccination in mice

Researchers analyzed the innate and adaptive responses to the mRNA-based BNT162b2 COVID-19 vaccine in mice.

18 Mar 2022

Convalescent antibodies do not enhance SARS-CoV-2 infection

Researchers investigated whether antibodies enhance severe acute respiratory syndrome coronavirus-2 infection.

16 Mar 2022

Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Researchers evaluate the virucidal effects of ELAH against SARS-CoV-2 and human coronavirus-229E in a nasal spray formulation.

15 Mar 2022

Skin biopsy can aid in early identification and differential diagnosis of Parkinson's disease

The diagnosis of Parkinson's disease (PD) is currently based on consensus clinical criteria. A novel study reported in the Journal of Parkinson's Disease has found that the presence of neuronal deposits of the biomarker phosphorylated alpha-synuclein (p-syn) in the brain and the skin of patients with PD distinguishes them from individuals with symptoms of parkinsonism due to the accumulation of another protein, tau.

15 Mar 2022

Novel nanocapsules offer solution for improving the efficacy of chemodynamic oncotherapy

In a paper published on Small recently, a collaborated research team led by Prof. WANG Hui from High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences reported the synthesis of hollow cuprous carbon (HCONC) by one-step hydrothermal method as well as their applications in efficient chemodynamic therapy.

14 Mar 2022

Neutralizing activity of therapeutic antibodies against clinical strains of BA.1 and BA.2 sub-lineages of the Omicron variant

Researchers conducted an in vitro analysis to assess the efficacy of monoclonal antibodies against the SARS-CoV-2 Omicron BA.2 and BA.1 variants.

14 Mar 2022

New insight about how blood clots are formed during wound healing

Research carried out by RCSI University of Medicine and Health Sciences has revealed new information about how blood clots are formed during wound healing.

11 Mar 2022

Potent pan-β-CoV human monoclonal antibody has in vivo activity in multiple animal models

Researchers evaluated the efficacy of viral spike domain 2-specific human monoclonal antibodies delivered intranasally, against all beta coronaviruses in hamsters and mice.

11 Mar 2022

in vivo News and Research

New implantable biotechnology produces and releases CAR-T cells for attacking tumors

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

New device based on concert hall acoustics enables noninvasive, ultrasound brain treatments

Monoclonal antibodies found to prevent lung inflammation in SARS-CoV-2-Omicron-infected mice

Novel monoclonal antibody found to have substantial neutralizing capacity against SARS-CoV-2 Omicron variant

Quantum dots can quantify specific types of cells inside deep tissues of the body

Novel optobiological system may shine light on protein aggregation in Parkinson's disease

BGI discovery could pave the way for advances in organ regeneration and synthetic biology

The obstacles to developing high-throughput 3D wound healing models

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

How does the non-structural protein 1 affect COVID-19 pathogenicity?

New virus-based approach for measuring variations in gene regulatory elements

Innate and adaptive immune responses to BNT162b2 vaccination in mice

Convalescent antibodies do not enhance SARS-CoV-2 infection

Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Skin biopsy can aid in early identification and differential diagnosis of Parkinson's disease

Novel nanocapsules offer solution for improving the efficacy of chemodynamic oncotherapy

Neutralizing activity of therapeutic antibodies against clinical strains of BA.1 and BA.2 sub-lineages of the Omicron variant

New insight about how blood clots are formed during wound healing

Potent pan-β-CoV human monoclonal antibody has in vivo activity in multiple animal models

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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