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Sister stem cells display considerable differences despite having identical DNA

Scientists have used a brand new technique for examining individual stem cells to uncover dramatic differences in the gene expression levels - which genes are turned 'up' or 'down'- between apparently identical 'sister' pairs.

27 Sep 2013

World’s first preclinical Magnetic Particle Imaging (MPI) system announced by Bruker

At the 2013 World Molecular Imaging Congress (WMIC, www.wmicmeeting.org), Bruker today announced the world’s first Magnetic Particle Imaging (MPI) system, an entirely new technology for preclinical imaging. The addition of MPI as a complementary preclinical imaging technique for disease studies, translational research and drug discovery, has significant potential in helping researchers gain new insights into disease processes at the organ, cellular and molecular level.

From Bruker BioSpin - NMR, EPR and Imaging 19 Sep 2013

Multimodal animal bed introduced by Bruker

Today, at the 2013 World Molecular Imaging Congress (WMIC), Bruker introduces a new multimodal animal bed enabling multiple sequential imaging sessions in preclinical research with robust repositioning between scans, while avoiding unwanted motion of the animal during the investigation. This optimizes results for image fusion, combined processing and evaluation of preclinical research applications requiring multiple imaging modalities across multiple systems.

From Bruker BioSpin - NMR, EPR and Imaging 19 Sep 2013

Using Serialization to Prevent Counterfeiting in the Pharmaceutical Industry

News-Medical speaks to Sue Miles about the dangers of counterfeit pharmaceutical products and how PCI are reducing the risk of counterfeiting during transit.

From Packaging Coordinators Inc. (PCI) 17 Sep 2013

Wake Forest Baptist conducts $24 million project to accelerate development of new therapies

Whether it's the Ebola virus or Sarin and Ricin, a key to responding to chemical or biological attacks is having effective antidotes at the ready. To accelerate the development of new therapies, Wake Forest Baptist Medical Center's Institute for Regenerative Medicine is leading a unique $24 million federally funded project to develop a "body on a chip" that will be used to develop these countermeasures.

12 Sep 2013

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

A family of microRNAs (miR-200) blocks cancer progression and metastasis by stifling a tumor's ability to weave new blood vessels to support itself, researchers at The University of Texas MD Anderson Cancer Center report today in Nature Communications.

12 Sep 2013

Improved lung function in patients with moderate asthma severity observed with investigational Tiotropium

Boehringer Ingelheim will present a pooled analysis of new data from the Phase 3 UniTinA-asthma® program at the European Respiratory Society (ERS) Annual Congress 2013 in Barcelona. The data from the individual MezzoTinA-asthma® Phase 3 studies (NCT01340209 and NCT00565266), from which the pooled data are derived, show the addition of tiotropium delivered via the Respimat® inhaler to medium-dose maintenance inhaled corticosteroid (ICS) therapy (defined as 400-800 µg budesonide/day or equivalent) improved lung function and provided sustained bronchodilation over 24 hours in patients with moderate asthma and airflow limitation. Tiotropium is being investigated to determine the medicine’s efficacy in treating asthma patients and is not currently approved for this indication.

11 Sep 2013

Patients with COPD show improvements in lung function with olodaterol

Data from the olodaterol Phase 3 clinical program, presented for the first time at the European Respiratory Society (ERS) Annual Congress 2013 in Barcelona, showed the addition of olodaterol 5 and 10 µg delivered once daily via the Respimat® inhaler provided improvements in lung function in patients with moderate to very severe chronic obstructive pulmonary disease (COPD).

10 Sep 2013

European launch of new version of REVIVE™ SE Thrombectomy Device for treatment of acute ischemic stroke announced by Codman Neuro

Codman Neuro*, part of DePuy Synthes Companies of Johnson & Johnson, announced the European launch of the REVIVE™ SE Thrombectomy Device, a next generation clot removal device offering enhanced navigation through the cerebral vasculature and rapid restoration of blood flow to the brain after an ischemic stroke.

9 Sep 2013

Once-daily COPD portfolio data from Novartis presented at European Respiratory Society (ERS) Annual Congress

Novartis announced new analyses of data for once-daily Ultibro® Breezhaler® (investigational QVA149 - indacaterol 85 mcg/glycopyrronium 43 mcg delivered dose, equivalent to 110 mcg/50 mcg metered dose per capsule), which showed significant improvements in lung function, shortness of breath and health-related quality of life for chronic obstructive pulmonary disease (COPD) patients versus all comparators1,2. These data were part of 39 respiratory abstracts presented at the European Respiratory Society (ERS) Annual Congress in Barcelona, Spain.

9 Sep 2013

New flexible microneedle patch allows drugs to deliver directly through skin

An assistant professor with the Virginia Tech - Wake Forest School of Biomedical Engineering has developed a flexible microneedle patch that allows drugs to be delivered directly and fully through the skin. The new patch can quicken drug delivery time while cutting waste, and can likely minimize side-effects in some cases, notable in vaccinations and cancer therapy.

7 Sep 2013

Scientists develop robotic systems for image-guided removal of hard-to-reach brain tumors

NIBIB-funded scientists and engineers are teaming up with neurosurgeons to develop technologies that enable less invasive, image-guided removal of hard-to-reach brain tumors.

6 Sep 2013

Technology used to treat cancer also functions as micro rocket for spacecraft

Nanosatellites are smartphone-sized spacecraft that can perform simple, yet valuable, space missions. Dozens of these little vehicles are now tirelessly orbiting the earth performing valuable functions for NASA, the Department of Defense and even private companies.

5 Sep 2013

Microencapsulated brain cancer drug may simplify treatment and provide tightly controlled therapy

Consistently uniform, easily manufactured microcapsules containing a brain cancer drug may simplify treatment and provide more tightly controlled therapy, according to Penn State researchers.

4 Sep 2013

Iron deficiency anemia may offer protection against malaria infection

Children in a malaria-endemic community in Ghana who received a micronutrient powder with iron did not have an increased incidence of malaria, according to a study in the September 4 issue of JAMA. Previous research has suggested that iron supplementation for children with iron deficiency in malaria-endemic areas may increase the risk of malaria.

4 Sep 2013

Obese people with high insulin levels likely to experience better blood vessel function following weight loss

Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have found that among obese people who had lost considerable weight, those with high insulin levels--a marker of insulin resistance in the body--were the most likely to experience better blood vessel function following the weight loss. These findings appear online in the Journal of the American College of Cardiology.

4 Sep 2013

Researchers pinpoint ways to counter effects of antibiotics-driven depletion of gut-dwelling bacteria

A new study by researchers at the Stanford University School of Medicine could help pinpoint ways to counter the effects of the antibiotics-driven depletion of friendly, gut-dwelling bacteria.

2 Sep 2013

Researchers receive $5M grant from agency to advance stem cell technologies in segmental bone defects

A Cedars-Sinai team of researchers led by principal investigator Dan Gazit, PhD, DMD, has been awarded a $5.18 million grant from California's stem cell research agency to advance stem cell technologies in segmental bone defects, a complex medical problem caused by large portions of bone tissue loss.

30 Aug 2013

Study shows ABL kinases have enhanced expression and activity in CML

Chronic Myelogenous Leukemia (CML) is a cancer of the white blood cells that is most commonly found in adults and in the elderly. Its incidence has been estimated to be 1 to 2 in 100,000 people. CML was the first cancer to be associated with a genetic abnormality, known as the Philadelphia Chromosome, which 95% of all CML patients carry in their cells.

28 Aug 2013

Two Genomic Pathways Tagged For Roles In Schizophrenia

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26 Aug 2013

micro News and Research

Sister stem cells display considerable differences despite having identical DNA

World’s first preclinical Magnetic Particle Imaging (MPI) system announced by Bruker

Multimodal animal bed introduced by Bruker

Using Serialization to Prevent Counterfeiting in the Pharmaceutical Industry

Wake Forest Baptist conducts $24 million project to accelerate development of new therapies

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

Improved lung function in patients with moderate asthma severity observed with investigational Tiotropium

Patients with COPD show improvements in lung function with olodaterol

European launch of new version of REVIVE™ SE Thrombectomy Device for treatment of acute ischemic stroke announced by Codman Neuro

Once-daily COPD portfolio data from Novartis presented at European Respiratory Society (ERS) Annual Congress

New flexible microneedle patch allows drugs to deliver directly through skin

Scientists develop robotic systems for image-guided removal of hard-to-reach brain tumors

Technology used to treat cancer also functions as micro rocket for spacecraft

Microencapsulated brain cancer drug may simplify treatment and provide tightly controlled therapy

Iron deficiency anemia may offer protection against malaria infection

Obese people with high insulin levels likely to experience better blood vessel function following weight loss

Researchers pinpoint ways to counter effects of antibiotics-driven depletion of gut-dwelling bacteria

Researchers receive $5M grant from agency to advance stem cell technologies in segmental bone defects

Study shows ABL kinases have enhanced expression and activity in CML

Two Genomic Pathways Tagged For Roles In Schizophrenia

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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