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New discovery could accelerate clinical translation of stem cell-based therapies

A team of scientists from the University of Colorado School of Medicine and the Charles C. Gates Center for Regenerative Medicine at CU Anschutz has reported a more efficient approach to reprogramming a patient's diseased skin cells into stem cells, raising hopes for future clinical trials and potential cures for critical illnesses.

23 Feb 2018

Researchers describe important step toward gene therapy for patients with Sandhoff disease

Babies with the rare, deadly genetic disorder Sandhoff disease begin to miss developmental milestones just months after birth. Lacking muscle tone, they never learn to sit up, develop heads too large to lift and eventually suffer uncontrollable seizures. There is no cure.

22 Feb 2018

Non-adherence to sleep apnea treatment linked to increased hospital readmissions

A study of patients with obstructive sleep apnea (OSA) suggests that non-adherence to continuous positive airway pressure (CPAP) therapy is significantly associated with increased 30-day hospital readmissions.

22 Feb 2018

Scientists decode molecular structure of healthy huntingtin protein

Mutations on a single gene, the huntingtin gene, are the cause of Huntington's disease. They lead to an incorrect form of the correspondent protein.

22 Feb 2018

Study sheds light on biological mechanisms that drive rare pediatric neurogenetic disorders

Researchers studying a rare genetic disorder that causes severe, progressive neurological problems in childhood have discovered insights into biological mechanisms that drive the disease, along with early clues that an amino acid supplement might offer a targeted therapy.

22 Feb 2018

Catheter-based procedure increases treatment options for mitral valve disease

Some heart patients haven't yet been able to access the growing trend toward minimally invasive procedures. A new clinical trial, though, makes a form of mitral valve repair an option without an open-heart surgery.

22 Feb 2018

After shooting, ‘honor how kids want to deal with their feelings’

With so much coverage of last week's grisly school shooting in Parkland, Fla., students, parents and others are struggling to cope.

22 Feb 2018

New data from VOYAGE 2 trial shows promising results for Janssen’s guselkumab treatment

The Janssen Pharmaceutical Companies of Johnson & Johnson announced today new data that showed a vast majority of patients with moderate to severe plaque psoriasis receiving TREMFYA (guselkumab), who achieved at least a 90 percent improvement in the Psoriasis Area and Severity Index (PASI 90) at week 28, maintained a PASI 90 response with continuous treatment through week 72.

From J&J Innovative Medicine 22 Feb 2018

Aggressive cancer stem cells can now be isolated successfully in a scientific breakthrough

University of Texas at Dallas researchers have managed to formulate a new technique by which they can isolate aggressive cells which can be the main cause behind metastasized cancers or cancers that have spread to other major organs from their primary site of occurrence.

22 Feb 2018

Duke researchers show how to retrain immune system of peanut-allergy mice

Treating food allergies might be a simple matter of teaching the immune system a new trick, researchers at Duke Health have found.

21 Feb 2018

Scientists reveal development of improved medicine to fight addiction

Drug addiction continues to plague vast numbers of people across the world, destroying and ending lives, while attempts to develop more effective pharmaceutical addiction treatments continue.

21 Feb 2018

Research opens up new avenue to minimize risks of transplants

A bone marrow transplant is often the only therapy available to save leukemia patients, but the risk of complications is high. In spite of devoting considerable time and effort to finding a suitable donor, nearly half of all patients experience an unwanted reaction of their immune system, which often attacks their skin and liver and in up to 50% of cases the intestines.

21 Feb 2018

Prophylactic use of haloperidol does not reduce delirium burden

Prophylactic use of the drug haloperidol does not help to prevent delirium in intensive care patients or improve their chances of survival. Therefore, there is no reason anymore to administer the drug as a preventive measure to reduce the burden of delirium.

21 Feb 2018

Low protein levels linked to posture and gait problems in Parkinson’s, finds study

A new study has linked low levels of alpha-synuclein in the cerebrospinal fluid of patients with Parkinson’s to postural instability and gait difficulty.

21 Feb 2018

Bad bedside manna: Bank loans signed in the hospital leave patients vulnerable

Laura Cameron, then three months pregnant, tripped and fell in a parking lot and landed in the emergency room last May — her blood pressure was low and she was scared and in pain. She was flat on her back and plugged into a saline drip when a hospital employee approached her gurney to discuss how she would pay her hospital bill.

21 Feb 2018

Australia lagging behind in psychedelic science renaissance

With research from the US showing that MDMA, or ecstasy, can effectively cure PTSD, it is time for Australia to embrace psychedelic science, according to Edith Cowan University addiction studies expert Dr Stephen Bright.

21 Feb 2018

French scientists develop new wearable laser that eradicates skin conditions

French scientists at ‘Texinov Medical Textiles’, have developed a knitted laser fabric that blasts the skin with light, giving treatment to inflamed skin or lesions over a 2 and a half hour appointment.

21 Feb 2018

USC-led researchers release dataset of brain scans from stroke patients

A USC-led team has now compiled, archived and shared one of the largest open-source datasets of brain scans from stroke patients via a study published Feb. 20 in Scientific Data, a Nature journal.

21 Feb 2018

Researchers target abnormal epigenetic mechanisms involved in childhood cancers

Several childhood cancer cell types show features of immature neural cells, and there is evidence suggesting that these tumors may arise from neural crest stem cells that underwent abnormal changes during embryonic development.

20 Feb 2018

AbbVie and Voyager Therapeutics collaborate to develop new treatments for tauopathies

AbbVie, a global biopharmaceutical company, and Voyager Therapeutics, Inc., a clinical-stage gene therapy company, today announced that they have entered into an exclusive strategic collaboration and option agreement to develop and commercialize vectorized antibodies directed against tau for the treatment of Alzheimer's disease and other neurodegenerative diseases.

20 Feb 2018

Therapy News and Research

New discovery could accelerate clinical translation of stem cell-based therapies

Researchers describe important step toward gene therapy for patients with Sandhoff disease

Non-adherence to sleep apnea treatment linked to increased hospital readmissions

Scientists decode molecular structure of healthy huntingtin protein

Study sheds light on biological mechanisms that drive rare pediatric neurogenetic disorders

Catheter-based procedure increases treatment options for mitral valve disease

After shooting, ‘honor how kids want to deal with their feelings’

New data from VOYAGE 2 trial shows promising results for Janssen’s guselkumab treatment

Aggressive cancer stem cells can now be isolated successfully in a scientific breakthrough

Duke researchers show how to retrain immune system of peanut-allergy mice

Scientists reveal development of improved medicine to fight addiction

Research opens up new avenue to minimize risks of transplants

Prophylactic use of haloperidol does not reduce delirium burden

Low protein levels linked to posture and gait problems in Parkinson’s, finds study

Bad bedside manna: Bank loans signed in the hospital leave patients vulnerable

Australia lagging behind in psychedelic science renaissance

French scientists develop new wearable laser that eradicates skin conditions

USC-led researchers release dataset of brain scans from stroke patients

Researchers target abnormal epigenetic mechanisms involved in childhood cancers

AbbVie and Voyager Therapeutics collaborate to develop new treatments for tauopathies

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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