Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Taking NSAIDs with other drugs can increase risk of upper GI bleeding, study finds

Nonsteroidal anti-inflammatory drugs (NSAIDs) - such as ibuprofen and aspirin - increase one's risk of upper gastrointestinal bleeding. When taken in combination with other drugs, this risk is significantly higher, according to new research appearing in the October issue of Gastroenterology, the official journal of the American Gastroenterological Association.

3 Oct 2014

Luminex gets FDA approval to add three new targets to xTAG Gastrointestinal Pathogen Panel

Luminex Corporation today announced it has received U.S. FDA clearance to add three new targets to its xTAG Gastrointestinal Pathogen Panel (GPP). The targets include Adenovirus 40/41, Entamoeba histolytica and Vibrio cholerae.

From Luminex 30 Sep 2014

Fecal microbiota transplantation officially recommended for effective treatment of C. difficile infection

The transplantation of faecal microbiota from a healthy donor has been shown in recent clinical studies to be a safe and highly effective treatment for recurrent Clostridium difficile (C. difficile) infection and is now recommended in European treatment guidelines.

29 Sep 2014

Taller individuals are less likely to develop esophageal cancer

Taller individuals are less likely to develop esophageal cancer and it's precursor, Barrett's esophagus, according to a new study1 in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

26 Sep 2014

Consensus statement on adequate bowel cleansing for colonoscopy

The success of a colonoscopy is closely linked to good bowel preparation, with poor bowel prep often resulting in missed precancerous lesions, according to new consensus guidelines released by the U.S. Multi-Society Task force on Colorectal Cancer.

22 Sep 2014

FDA approves Contrave extended-release tablets for chronic weight management

Takeda Pharmaceuticals U.S.A., Inc. and Orexigen® Therapeutics, Inc. jointly announced today that the U.S. Food and Drug Administration has approved Contrave® extended-release tablets as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition.

11 Sep 2014

Restarting infliximab therapy after drug holiday is safe for patients with IBD

Restarting infliximab therapy after a drug holiday is safe and effective for patients with inflammatory bowel disease (IBD), according to a new study1 in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

8 Sep 2014

Researchers discover genetic factors involved in development of early-onset ulcerative colitis

UCLA researchers were part of a team that has discovered the interplay of several genetic factors that may be involved in the development of early-onset ulcerative colitis, a severe type of inflammatory bowel disease.

4 Sep 2014

Irinotecan-based therapy improves survival rates for patients with stage III colon cancer

A subset of patients with stage III colon cancer had improved survival rates when treated with irinotecan-based therapy, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association.

29 Aug 2014

Actavis files ANDA for generic version of Neupro

Actavis plc today confirmed that it has filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration (FDA) seeking approval to market Rotigotine Extended-release Transdermal Film, 1 mg/24 hr, 2mg/24 hr, 3 mg/24hr, 4 mg/24 hr, 6mg/24hr, and 8 mg/24 hr.

25 Aug 2014

Actavis reports positive results from ceftazidime-avibactam Phase III studies in cIAI patients

Actavis plc today confirmed positive topline results from RECLAIM-1 and -2, pivotal Phase III studies evaluating the potential for the investigational antibiotic, ceftazidime-avibactam as a treatment for adult hospitalized patients with complicated intra-abdominal infections.

19 Aug 2014

Research roundup: Benefits of smaller practices; Rx price growth; fixing Medicare claims reviews

The Centers for Medicare & Medicaid Services within the Department of Health and Human Services has taken steps to prevent its contractors from conducting certain duplicative postpayment claims reviews - reviews of the same claims that are not permitted by the agency - but CMS neither has reliable data nor provides sufficient oversight and guidance to measure and fully prevent duplication.

16 Aug 2014

VolitionRx installs automated liquid handling system to increase rate of blood sample analysis

VolitionRx Limited, a life sciences company focused on developing blood-based diagnostic tests for different types of cancer, today announced it has installed a Tecan EVO200 automated liquid handling system in its Namur, Belgium laboratory.

13 Aug 2014

Bacteria may depend more on gastrointestinal age than on environmental factors in babies

Scientists believe babies are born with digestive systems containing few or no bacteria. Their guts then quickly become colonized by microbes — good and bad — as they nurse or take bottles, receive medication and even as they are passed from one adoring relative to another.

12 Aug 2014

High school recipients receive $2,500 to support digestive disease research projects

The American Gastroenterological Association (AGA) Research Foundation has announced the 2014 AGA-Eli and Edythe Broad Student Research Fellowship Award recipients. This award stimulates interest in digestive disease research among high school students by supporting budding scientists' research projects.

8 Aug 2014

New method of growing human cells may help develop tailor-made therapies for GI conditions

A method of growing human cells from tissue removed from a patient's gastrointestinal (GI) tract eventually may help scientists develop tailor-made therapies for inflammatory bowel disease and other GI conditions.

8 Aug 2014

Access Pharmaceuticals enters into exclusive license agreement with Norgine

ACCESS PHARMACEUTICALS, INC., an emerging biopharmaceutical company, today announced that it had entered into an exclusive license agreement with Norgine B.V., a leading independent European specialty pharmaceutical company, for the commercialization of MuGard in Europe.

7 Aug 2014

African Americans less likely to engage in CRC screening in VA healthcare system

According to researchers in California, African Americans' participation in colorectal cancer screening is low and the use of colonoscopy infrequent despite similar access to care across races in a Veterans Affairs healthcare system.

7 Aug 2014

Immunosuppressive drugs increase risk of myeloid disorders among IBD patients

Immunosuppressive drugs called thiopurines have been found to increase the risk of myeloid disorders, such as acute myeloid leukemia and myelodysplastic syndrome, a rare bone marrow disorder, seven-fold among inflammatory bowel disease (IBD) patients.

7 Aug 2014

Home based medical care for frail elders reduces Medicare costs by 17%

MedStar Washington Hospital Center geriatricians found that when medical care for frail elders with advanced illness shifts to the home, total Medicare costs were reduced by 17 percent during a two-year period.

6 Aug 2014

Gastroenterology News and Research

Further Reading

Taking NSAIDs with other drugs can increase risk of upper GI bleeding, study finds

Luminex gets FDA approval to add three new targets to xTAG Gastrointestinal Pathogen Panel

Fecal microbiota transplantation officially recommended for effective treatment of C. difficile infection

Taller individuals are less likely to develop esophageal cancer

Consensus statement on adequate bowel cleansing for colonoscopy

FDA approves Contrave extended-release tablets for chronic weight management

Restarting infliximab therapy after drug holiday is safe for patients with IBD

Researchers discover genetic factors involved in development of early-onset ulcerative colitis

Irinotecan-based therapy improves survival rates for patients with stage III colon cancer

Actavis files ANDA for generic version of Neupro

Actavis reports positive results from ceftazidime-avibactam Phase III studies in cIAI patients

Research roundup: Benefits of smaller practices; Rx price growth; fixing Medicare claims reviews

VolitionRx installs automated liquid handling system to increase rate of blood sample analysis

Bacteria may depend more on gastrointestinal age than on environmental factors in babies

High school recipients receive $2,500 to support digestive disease research projects

New method of growing human cells may help develop tailor-made therapies for GI conditions

Access Pharmaceuticals enters into exclusive license agreement with Norgine

African Americans less likely to engage in CRC screening in VA healthcare system

Immunosuppressive drugs increase risk of myeloid disorders among IBD patients

Home based medical care for frail elders reduces Medicare costs by 17%

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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