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Researchers take important step toward finding protein biomarkers during cancer surgery

Isabelle Fournier and her team are out to change surgical oncology. "Better surgery is associated with better prognosis and higher survival," said Fournier, a professor at the University of Lille and co-director of a proteomics center of INSERM, the French national institute of health.

24 May 2018

UCI research team uncovers new unexpected mode of neurotransmitter-based communication

Researchers at the University of California, Irvine School of Medicine have discovered the first example of a novel mode of neurotransmitter-based communication.

22 May 2018

Researchers use MR spectroscopy to investigate mechanisms behind targeted treatment for gliomas

Using a novel imaging method, a Massachusetts General Hospital research team is investigating the mechanisms behind a potential targeted treatment for a subtype of the deadly brains tumors called gliomas.

21 May 2018

Study gives insight into how signals enter cancer cells and drive aggressive growth

The outside of a cancer cell is bombarded by signals. They come from the immune system, supporting tissues and other structures. But how do those signals impact cancer?

14 May 2018

Changing metabolic states of intestinal bacteria have an effect on MAIT defense cells

A little-explored group of immune cells plays an important role in the regulation of intestinal bacteria.

9 May 2018

Key metabolites shed by gut bacteria can help protect from inflammation, study finds

Researchers at Tufts University have elucidated a mechanism by which the "good" bacteria that reside in our gastrointestinal tract can help protect us from inflammation, and how their disruption (dysbiosis) can increase the susceptibility of the liver to more harmful forms of disease.

4 May 2018

Walnut consumption impacts gut microbiota and offers many health benefits

Diets rich in nuts, such as walnuts, have been shown to play a role in heart health and in reducing colorectal cancer.

4 May 2018

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

One major hallmark of cancer cells is their ability to adapt to stressful conditions such as nutrient deprivation. Rapidly growing tumor cells must compete for the ever-diminishing supply of nutrients in the surrounding environment to survive and proliferate. Targeting these adaptive mechanisms represents a promising approach for cancer therapeutics.

3 May 2018

Moving beyond traditional 'magic bullet' approach for discovering new drugs

It's time to move beyond the traditional 'magic bullet' approach for discovering new drugs and start leveraging the full complexity of Mother Nature, say Vanderbilt Professor of Chemistry Brian Bachmann and Assistant Professor of Cell and Developmental Biology Jonathan Irish.

3 May 2018

Researchers show novel relationship between gut microbiome and atherosclerosis

Researchers at Western University and Lawson Health Research Institute have shown a novel relationship between the intestinal microbiome and atherosclerosis, one of the major causes of heart attack and stroke.

3 May 2018

Researchers find novel approach for in vivo real-time monitoring of metabolites

Real-time monitoring of the dynamics of endogenous molecules in organisms is an important aspect in the study of diseases.

2 May 2018

Western diets promote bacterial growth in the small intestine, increase fat digestion and absorption

A researcher at Midwestern University led a new study showing that Western diets, high in fat and simple sugar, promote the growth of bacteria in the small intestine that increase fat digestion and absorption.

27 Apr 2018

Pepper plant metabolizes antibiotic in personal care products

It sometimes can be hard to find toothpastes, soaps and other toiletries without antibiotics. Their popularity has caused an increase in environmental levels of antimicrobial substances, such as triclocarban (TCC), which end up in the water and soil used to grow crops.

18 Apr 2018

Old proteins on historical artifacts provide insight into the past

"Dead men tell no tales" is a common saying, but according to an article in Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society, the old proteins on historical artifacts, such as manuscripts and clothing, can tell quite a yarn.

12 Apr 2018

Specific small-bowel microbes regulate digestion and absorption of fats, study shows

Although the vast majority of research on the gut microbiome has focused on bacteria in the large intestine, a new study - one of a few to concentrate on microbes in the upper gastrointestinal tract - shows how the typical calorie-dense western diet can induce expansion of microbes that promote the digestion and absorption of high-fat foods.

11 Apr 2018

Researchers discover how intestinal bacteria can influence blood glucose and lipid concentrations

Intestinal bacteria have attracted recent attention since they were discovered to influence various physiological functions and diseases in humans.

10 Apr 2018

New links found between Mediterranean diet and healthy aging outcomes

A series of six articles appearing in the March issue of The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences finds new correlations between a Mediterranean diet and healthy aging outcomes -- while also underscoring the need for careful approaches to the use of data in order to measure the diet's potential benefits.

30 Mar 2018

Researchers aim to reveal new direction for Barth syndrome treatment

The Barth Syndrome Foundation recently announced awardees from its 2017 grant cycle. Miriam Greenberg, Ph.D., professor of biological sciences in the College of Liberal Arts and Sciences at Wayne State University and a resident of Ann Arbor, Michigan, received a one-year, $50,000 grant for the project, "Cardiolipin activates pyruvate dehydrogenase (PDH) - a potential new target for treatment of Barth syndrome."

28 Mar 2018

Measurement of tumor's metabolic activity could help determine prostate cancer prognosis

A new approach to analyzing prostate gland tissue may help address a major challenge in treating prostate cancer - determining which tumors are unlikely to progress and which could be life threatening and require treatment.

27 Mar 2018

New study shows connection between coffee and cannabis

It's well known that a morning cup of joe jolts you awake. But scientists have discovered coffee affects your metabolism in dozens of other ways, including your metabolism of steroids and the neurotransmitters typically linked to cannabis, reports a new study from Northwestern Medicine.

15 Mar 2018

Metabolites News and Research

Researchers take important step toward finding protein biomarkers during cancer surgery

UCI research team uncovers new unexpected mode of neurotransmitter-based communication

Researchers use MR spectroscopy to investigate mechanisms behind targeted treatment for gliomas

Study gives insight into how signals enter cancer cells and drive aggressive growth

Changing metabolic states of intestinal bacteria have an effect on MAIT defense cells

Key metabolites shed by gut bacteria can help protect from inflammation, study finds

Walnut consumption impacts gut microbiota and offers many health benefits

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

Moving beyond traditional 'magic bullet' approach for discovering new drugs

Researchers show novel relationship between gut microbiome and atherosclerosis

Researchers find novel approach for in vivo real-time monitoring of metabolites

Western diets promote bacterial growth in the small intestine, increase fat digestion and absorption

Pepper plant metabolizes antibiotic in personal care products

Old proteins on historical artifacts provide insight into the past

Specific small-bowel microbes regulate digestion and absorption of fats, study shows

Researchers discover how intestinal bacteria can influence blood glucose and lipid concentrations

New links found between Mediterranean diet and healthy aging outcomes

Researchers aim to reveal new direction for Barth syndrome treatment

Measurement of tumor's metabolic activity could help determine prostate cancer prognosis

New study shows connection between coffee and cannabis

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