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Immunotherapy more effective than chemotherapy for children, young adults with relapsed B-ALL

New findings from a clinical trial show that treatment with the immunotherapy drug blinatumomab is superior to standard chemotherapy for children and young adults with high- or intermediate-risk B-cell acute lymphoblastic leukemia that has relapsed.

10 Dec 2019

In campaign to stop teen vaping, states turn to tried-and-true remedy: taxes

Kathleen Hambleton once used to spend $100 a week on Marlboro Reds.

10 Dec 2019

Rutgers researchers identify small mutations for AML and MDS through deep DNA sequencing

Deep DNA sequencing analysis conducted by Rutgers Cancer Institute of New Jersey investigators examining genomic differences within tumors for prediction of disease relapse in certain hematologic malignancies has identified small mutations.

9 Dec 2019

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with mantle cell lymphoma resistant to prior therapies may benefit from treatment with CD19-targeting chimeric antigen receptor (CAR) T-cell therapy.

9 Dec 2019

Stem cell transplant following treatment with PD-1 inhibitor is safe, effective for patients with Hodgkin lymphoma

A new analysis shows that a donor stem cell transplant following treatment with an immune checkpoint inhibitor is generally safe and produces good outcomes for patients with Hodgkin lymphoma, easing concerns that these patients are at heightened risk for severe immune-related complications.

9 Dec 2019

Important biomarker may help in determining prognosis of brain cancer patients

A common virus that is harmless to most individuals may produce an important biomarker in determining the prognosis of brain cancer patients, according to a recent study published by a student researcher at the University of Cincinnati.

9 Dec 2019

$Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission$

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

A new, experimental immunotherapy can put patients with B-cell non-Hodgkin lymphoma (NHL) that is resistant to or has come back after multiple other therapies, including CAR T therapy, into remission.

8 Dec 2019

Adding venetoclax to transplant conditioning regimen shows promise in patients with myeloid cancers

For patients with high-risk myeloid cancers undergoing a donor stem cell transplant, adding the targeted drug venetoclax to a reduced-intensity drug regimen prior to transplant is safe and does not impair the ability of the donor cells to take root in recipients' bodies, a study led by Dana-Farber Cancer Institute researchers suggests.

8 Dec 2019

Genetic features of AML in older patients can predict outcomes after stem cell transplant

For older patients with acute myeloid leukemia, the prospects for success of a stem cell transplant can often be predicted based on the particular set of genetic mutations within the tumor cells, investigators at Dana-Farber Cancer Institute and other research centers will report today at the 61st American Society of Hematology (ASH) Annual Meeting.

8 Dec 2019

New startup aims to prevent reperfusion-related organ damage after liver transplant

Roughly 65 years ago, the first human organ transplant was successfully performed. A decade later, heart and liver transplants became possible. Now, a startup founded by researchers from the Medical University of South Carolina and elsewhere hopes to bring about the next major breakthrough.

8 Dec 2019

Pilot clinical trial tests new treatment for type 1 diabetes

Type 1 diabetes is a chronic condition in which the body's own immune system attacks and destroys beta cells in the pancreas. Once the beta cells are destroyed, the pancreas can no longer produce insulin. Currently, there is no cure for T1D and treatment focuses on managing blood sugar levels.

6 Dec 2019

Preoperative rehabilitation program for older adults leads to better outcomes

Older adults who "train" for a major operation by exercising, eating a healthy diet, and practicing stress reduction techniques preoperatively have shorter hospital stays and are more likely to return to their own homes afterward rather than another facility, compared with similar patients who do not participate in preoperative rehabilitation, according to research findings.

5 Dec 2019

$Nerve signaling pathway crucial to healing fractures, study shows$

Nerve signaling pathway crucial to healing fractures, study shows

Sticks and stones may break one's bones, but healing them requires the production of a protein signal that stimulates the generation, growth and spread of vital nerve cells, or neurons, throughout the injured area.

5 Dec 2019

No differences found in survival, acute rejection in patients receiving lungs from increased-risk donors

Cleveland Clinic researchers have found that using lungs from donors who are considered high risk for certain infectious diseases compared to standard risk donors results in similar one-year survival for recipients. In addition, researchers saw no difference in rejection or graft (donor lung) survival after one year in patients receiving lungs from increased-risk donors.

5 Dec 2019

Adding post-transplant chemotherapy to standard treatment improves remission of allogeneic transplant patients

Investigators in the Blood and Marrow Transplant Program at Rutgers Cancer Institute of New Jersey compared outcomes for patients having undergone allogeneic stem cell transplant when post-transplant cyclophosphamide (PCy, a type of chemotherapy) was added as part of standard treatment to prevent disease through an immune response (immunoprophylaxis) than if this standard treatment was given alone.

5 Dec 2019

New dialysis approach provides high levels of satisfaction for kidney patients

A new study reports high levels of patient satisfaction with a minimally invasive approach to creating vascular access for kidney patients who require hemodialysis.

5 Dec 2019

California surprise-billing law protects patients but aggravates many doctors

More than two years after California's surprise-billing law took effect, there's one thing on which consumer advocates, doctors and insurers all agree: The law has been effective at protecting many people from bills they might have been saddled with from doctors who aren't in their insurance network.

5 Dec 2019

New program receives national recognition for treating hypertrophic cardiomyopathy

When Kayla Green was first diagnosed with hypertrophic cardiomyopathy, she felt vindicated.

4 Dec 2019

A major step toward preventing GvHD in patients receiving bone marrow transplants

A drug used for rheumatoid arthritis has moved a step closer to FDA approval for a desperately needed new use.

4 Dec 2019

Cleveland Clinic to study ecological, evolutionary mechanisms that contribute to lung cancer

Jacob Scott, M.D., Ph.D., a physician researcher from Cleveland Clinic's Department of Translational Hematology and Oncology Research, recently received a $2.8 million grant from the National Cancer Institute, part of the National Institutes of Health, to study how ecological and evolutionary mechanisms contribute to lung cancer development and progression, and how the interplay between these mechanisms may provide novel treatment insights.

4 Dec 2019

Transplant News and Research

Immunotherapy more effective than chemotherapy for children, young adults with relapsed B-ALL

In campaign to stop teen vaping, states turn to tried-and-true remedy: taxes

Rutgers researchers identify small mutations for AML and MDS through deep DNA sequencing

Relapsed mantle cell lymphoma patients may benefit from CAR T-cell therapy

Stem cell transplant following treatment with PD-1 inhibitor is safe, effective for patients with Hodgkin lymphoma

Important biomarker may help in determining prognosis of brain cancer patients

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

Adding venetoclax to transplant conditioning regimen shows promise in patients with myeloid cancers

Genetic features of AML in older patients can predict outcomes after stem cell transplant

New startup aims to prevent reperfusion-related organ damage after liver transplant

Pilot clinical trial tests new treatment for type 1 diabetes

Preoperative rehabilitation program for older adults leads to better outcomes

Nerve signaling pathway crucial to healing fractures, study shows

No differences found in survival, acute rejection in patients receiving lungs from increased-risk donors

Adding post-transplant chemotherapy to standard treatment improves remission of allogeneic transplant patients

New dialysis approach provides high levels of satisfaction for kidney patients

California surprise-billing law protects patients but aggravates many doctors

New program receives national recognition for treating hypertrophic cardiomyopathy

A major step toward preventing GvHD in patients receiving bone marrow transplants

Cleveland Clinic to study ecological, evolutionary mechanisms that contribute to lung cancer

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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