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Researchers propose novel solution to minimize recurrent caries

When patients go to the dentist to fill a cavity, they're trying to solve a problem -- not create a new one. But many dental patients get some bad news: bacteria can dig under their tooth-colored fillings and cause new cavities, called recurrent caries.

30 Jan 2018

Computational approach can help identify chemoresistant potential targets in cancer stem cells

In cancer, one of the most important features is the methylation of deoxycytosine to form 5-methylcytosine (5mC). DNA methylation is a process by which methyl groups (structural units of organic compounds consisting of three hydrogen atoms bonded to a carbon atom) are added to the DNA molecule.

30 Jan 2018

NUS scientists develop new way to wirelessly deliver light for cancer treatment

A team of scientists from the National University of Singapore has developed a way to wirelessly deliver light into deep regions of the body to activate light-sensitive drugs for photodynamic therapy.

30 Jan 2018

Idaho ‘pushing envelope’ with health insurance plan. Can it do that?

For the past year, the Trump administration and Republicans in Congress have led a charge to roll back the Affordable Care Act, signaling an openness to state changes.

30 Jan 2018

Muscles possess 'memory' of earlier growth at the DNA level, study shows

A study led by researchers at Keele University has shown for the first time that human muscles possess a 'memory' of earlier growth - at the DNA level.

30 Jan 2018

Study lays groundwork for using PD-1 inhibitors against aggressive form of pediatric brain cancer

One type of immunotherapy removes a genetic blindfold that cancer uses to hide from the immune system. These "PD-1 inhibitors", including drugs like pembrolizumab, nivolumab and atezolizumab, have proven useful and have even in some cases revolutionized the treatment of common adult cancers ranging from melanoma, to lung cancer, to kidney cancer and more.

30 Jan 2018

Treatment quality for heart failure should be measured on guideline adherence, not patient volume

Adherence to treatment guidelines, not patient volume, is a better method to predict treatment outcome in patients with heart failure, finds new study.

30 Jan 2018

The effects of Huntington’s disease can be seen as early as conception, finds new study

In a breakthrough study, scientists at the Rockefeller University have observed the effects of Huntington’s disease in neurons as early as conception.

30 Jan 2018

Psychiatric drugs do not appear to be overprescribed for children, study reveals

A new study at Columbia University Irving Medical Center challenges the popular notion that psychiatric medications are overprescribed in children and adolescents in the U.S.

30 Jan 2018

Vitamin deficiency prevents proliferation of cancer stem cells

DPI effectively switches off the cancer stem cells, preventing their proliferation. "It's extraordinary; the cells just sit there as if in a state of suspended animation" explains Professor Michael Lisanti, Chair of Translational Medicine and lead investigator.

30 Jan 2018

New molecular research shows how antidepressants work

New molecular research shows how chemically diverse drugs used to treat depression and anxiety disorders interact with the protein that transports serotonin in the brain.

29 Jan 2018

Groundbreaking study broadens spectrum of cryopyrin-associated periodic syndromes

A research team from the University of Helsinki, Helsinki University Hospital and Folkhälsan Institute of Genetics in Helsinki, Finland, have identified a new genetic mutation that alters the function of cryopyrin and leads to a life-long periodic inflammation of the cornea, the transparent window of the human eye. Patients who carry the mutation also develop corneal opacities that compromise vision.

29 Jan 2018

Blood pressure and cholesterol lowering drugs do not negatively affect erectile function, study says

New study provides reassurance for men taking blood pressure and cholesterol modifying medications, reports the Canadian Journal of Cardiology.

29 Jan 2018

Researchers win $6.5 million NIH grant to personalize diagnosis and treatment of psoriasis

An experienced interdisciplinary team of psoriasis and computational researchers from Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center has received a $6.5M, 5-year grant from the National Institute of Arthritis, Musculoskeletal and Skin Diseases.

29 Jan 2018

New study sheds light on important protein involved in memory formation

A team of researchers have made important discoveries about a protein called AKT that is key to the formation of new memories.

29 Jan 2018

Viral replication process weak spot may help develop cure for infections

Researchers at the Morgridge Institute for Research believe they have identified a weak spot in the replication process of positive-strand RNA viruses, which could yield treatment for viral infections such as Zika, Polio, Chikungunya, Hepatitis C and even common cold viruses.

29 Jan 2018

Death in the family: An uncle’s overdose spurs Medicaid official to change course

Andrey Ostrovsky's family did not discuss what killed his uncle. He was young, not quite two weeks past his 45th birthday, when he died, and he had lost touch with loved ones in his final months. Ostrovsky speculated he had committed suicide.

29 Jan 2018

Researchers reveal important role of estrogen in neuroblastoma

The female sex hormone estrogen can perform an important role in neuroblastoma, a form of cancer mainly affecting young children.

29 Jan 2018

FDA approves new radioactive drug for treatment of rare digestive tract cancers

The U.S. Food and Drug Administration today approved Lutathera (lutetium Lu 177 dotatate) for the treatment of a type of cancer that affects the pancreas or gastrointestinal tract called gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

29 Jan 2018

Study contradicts long-established dogma about eye immunity

A person needs immune-suppressive drugs for organ transplants but not typically for transplants in the eye. How come? Like a few other parts of the body, some components of the eye, like the lens, don't have direct access to vessels that deliver immune cells.

27 Jan 2018

Drugs News and Research

Researchers propose novel solution to minimize recurrent caries

Computational approach can help identify chemoresistant potential targets in cancer stem cells

NUS scientists develop new way to wirelessly deliver light for cancer treatment

Idaho ‘pushing envelope’ with health insurance plan. Can it do that?

Muscles possess 'memory' of earlier growth at the DNA level, study shows

Study lays groundwork for using PD-1 inhibitors against aggressive form of pediatric brain cancer

Treatment quality for heart failure should be measured on guideline adherence, not patient volume

The effects of Huntington’s disease can be seen as early as conception, finds new study

Psychiatric drugs do not appear to be overprescribed for children, study reveals

Vitamin deficiency prevents proliferation of cancer stem cells

New molecular research shows how antidepressants work

Groundbreaking study broadens spectrum of cryopyrin-associated periodic syndromes

Blood pressure and cholesterol lowering drugs do not negatively affect erectile function, study says

Researchers win $6.5 million NIH grant to personalize diagnosis and treatment of psoriasis

New study sheds light on important protein involved in memory formation

Viral replication process weak spot may help develop cure for infections

Death in the family: An uncle’s overdose spurs Medicaid official to change course

Researchers reveal important role of estrogen in neuroblastoma

FDA approves new radioactive drug for treatment of rare digestive tract cancers

Study contradicts long-established dogma about eye immunity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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