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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

JANUMET results in greater blood sugar reductions in patients with type 2 diabetes compared to pioglitazone

New data were presented at the American Diabetes Association 70th Annual Scientific Sessions from a study comparing JANUMET (sitagliptin/metformin) to pioglitazone. In this study, JANUMET resulted in significantly greater blood sugar reductions in patients with type 2 diabetes compared with pioglitazone.

28 Jun 2010

Researchers discover genetic links to kidney failure, diabetic kidney disease

Researchers at the Translational Genomics Research Institute will make two presentations at this week's 70th Scientific Sessions of the American Diabetes Association, June 25-29, in Orlando, Florida.

28 Jun 2010

Genomic analysis leads to more effective diagnostic tests, treatment options for prostate cancer: Study

A unique collaboration among physician-scientists at Memorial Sloan-Kettering Cancer Center has yielded the most comprehensive genomic analysis of prostate cancer to date. "Genomic studies in other cancer types have resulted in new drug targets and strategies to classify patients into clinically meaningful subgroups that improve treatment decisions," said senior study author Charles Sawyers, Chair of the Human Oncology and Pathogenesis Program at MSKCC and a HHMI investigator. "This first -ever database of its type brings us one step closer to achieving that goal in prostate cancer."

28 Jun 2010

PARP inhibitors may be effective in men with prostate cancer due to BRCA2 alteration: Researchers

The way prostate cancer develops in men who have an altered 'breast cancer gene' is the same route by which breast cancer develops in women with the same mutation, reveals a study published in PLoS Genetics today (Thursday).

25 Jun 2010

Specific virus can interact with mutation in host's genes to trigger diseases: Scientists

Scientists have shown that a specific virus can interact with a mutation in the host's genes to trigger disease. The observation may help explain why many people with disease risk genes do not actually develop disease.

25 Jun 2010

Impact of oil spill on humans and wildlife

University of Rhode Island Pharmacy Professor Bongsup Cho knows there are cancer-causing chemicals in diesel fumes and cigarette smoke.

25 Jun 2010

Gene therapy holds promise in treating cancer, cardiovascular and neurodegenerative diseases

EUREKA project E! 3371 Gene Transfer Agents has made great advances in the development of novel non-viral carriers able to introduce genetic material into the target cells.

25 Jun 2010

Merck's DULERA Inhalation Aerosol for asthma receives FDA approval

Merck today announced that the U.S. Food and Drug Administration (FDA) has approved DULERA® (mometasone furoate and formoterol fumarate dihydrate) Inhalation Aerosol, a new fixed-dose combination asthma treatment for patients 12 years of age and older. DULERA is not indicated for the relief of acute bronchospasm. DULERA combines an inhaled corticosteroid (mometasone furoate) with a long-acting beta2-agonist (formoterol fumarate).

24 Jun 2010

UNC team provides first example of successful radiomitigation in mammals

While radiation has therapeutic uses, too much radiation is damaging to cells. The most important acute side effect of radiation poisoning is damage to the bone marrow. The bone marrow produces all the normal blood cells, and therefore a high dose of radiation can lead to low blood counts of red cells, platelets and white blood cells.

24 Jun 2010

People with certain chitinase gene variants at increased risk of severe asthma attacks

Exposure to high levels of fungus may increase the risk of severe asthma attacks among people with certain chitinase gene variants, according to a study from Harvard Medical School, Harvard Pilgrim Health Care Institute and Brigham and Women's Hospital.

24 Jun 2010

Researchers find why patients with XPV are more susceptible to skin cancer

Researchers from Mount Sinai School of Medicine have found why patients with a variant form of xeroderma pigmentosum, an inherited genetic disorder characterized by extreme sensitivity to the sun, are more susceptible to skin cancers than the general population. The data are published in the current issue of the journal Nature. Their finding sets the stage for research into therapies that would help protect people with XPV from developing skin cancers.

24 Jun 2010

Risk, incidence of VTE differs between races

A new study of 1,960 White-Americans and 368 Black-Americans with objectively diagnosed venous thromboembolism (VTE) showed that, compared to Whites, Blacks had a significantly higher proportion with pulmonary embolism (PE), including idiopathic PE among Black women, and a significantly higher proportion of Blacks with VTE were women (71% vs 61% for Whites) The study is published today in the American Journal of Hematology.

24 Jun 2010

Increased drug development cost drives pharma companies to seek better opportunities in emerging markets

The increased cost of drug development has impelled pharmaceutical companies to seek better opportunities in emerging markets to successfully expand and sell their products. Most pharmaceutical companies consider emerging markets lucrative due to their economical infrastructure and manpower costs and a significant untapped market potential with a large population.

24 Jun 2010

Mutation in ion channel that changes its dynamics is implicated in epilepsy: Scientists

In 2004, Washington University in St. Lous researcher Jianmin Cui was handed a puzzling clue to the structure of an ion channel his lab had been studying for five years.

24 Jun 2010

NIH to invest $25M over five years for international collaboration on genetic research in Africa

The NIH on Tuesday announced a partnership with Wellcome Trust and the African Society for Human Genetics that will enable African researchers to "use the latest genetic and clinical technology to study common health problems, such as cardiovascular disease, cancer and other diseases," VOA News reports (DeCapua, 6/22).

24 Jun 2010

Positive results from Phase II PK study for Topical Interferon Alpha-2b announced

Helix BioPharma Corp. today announced positive Phase II pharmacokinetic findings for Topical Interferon Alpha-2b in patients with low-grade cervical lesions.

24 Jun 2010

Tikcro Technologies reports net income of $1.9 million for first-quarter 2010

Tikcro Technologies Ltd. today reported results for the first quarter ended March 31, 2010.

24 Jun 2010

MDI raises $1.4M as part of follow-on to its $3.3M Series C financing round

Molecular Detection Inc., a company developing Detect-Ready assays designed to increase the speed and accuracy of infectious disease diagnosis, today announced the first close of a new financing. The financing was led by MentorTech Ventures II, LP and included Robin Hood Ventures, Elm Spring Holdings and the Mid-Atlantic Angel Group Fund I and II, LP, all existing investors. The company raised $1.4 million as part of a follow-on to its $3.3 million Series C round announced in late 2009.

23 Jun 2010

Researchers develop experimental approaches, analysis tools to understand phenotypic expression

The Human Genome Project, along with numerous parallel efforts to solve the DNA sequences of hundreds of animal, plant, fungal, and microbe genomes in the last few decades, has produced enormous amounts of genetic data with which researchers are struggling to keep pace.

23 Jun 2010

OvaGene Oncology opens new advanced molecular research and clinical laboratory facility

OvaGene Oncology Inc., a biotechnology company specializing in the development and commercialization of personalized DNA-based diagnostics for gynecologic cancer, announced today the opening of its new clinical and research laboratory in Irvine, California. This state-of-the-art facility will serve as the central headquarters for operations, research, and molecular clinical lab testing.

23 Jun 2010

DNA News and Research

Further Reading

JANUMET results in greater blood sugar reductions in patients with type 2 diabetes compared to pioglitazone

Researchers discover genetic links to kidney failure, diabetic kidney disease

Genomic analysis leads to more effective diagnostic tests, treatment options for prostate cancer: Study

PARP inhibitors may be effective in men with prostate cancer due to BRCA2 alteration: Researchers

Specific virus can interact with mutation in host's genes to trigger diseases: Scientists

Impact of oil spill on humans and wildlife

Gene therapy holds promise in treating cancer, cardiovascular and neurodegenerative diseases

Merck's DULERA Inhalation Aerosol for asthma receives FDA approval

UNC team provides first example of successful radiomitigation in mammals

People with certain chitinase gene variants at increased risk of severe asthma attacks

Researchers find why patients with XPV are more susceptible to skin cancer

Risk, incidence of VTE differs between races

Increased drug development cost drives pharma companies to seek better opportunities in emerging markets

Mutation in ion channel that changes its dynamics is implicated in epilepsy: Scientists

NIH to invest $25M over five years for international collaboration on genetic research in Africa

Positive results from Phase II PK study for Topical Interferon Alpha-2b announced

Tikcro Technologies reports net income of $1.9 million for first-quarter 2010

MDI raises $1.4M as part of follow-on to its $3.3M Series C financing round

Researchers develop experimental approaches, analysis tools to understand phenotypic expression

OvaGene Oncology opens new advanced molecular research and clinical laboratory facility

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