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Precision editing of gut bacteria reduces inflammation in mouse model of colitis

UT Southwestern Medical Center researchers have used precision editing of the bacterial populations in the gut to prevent or reduce the severity of inflammation in a mouse model of colitis.

5 Jan 2018

Researchers use Quest MRI to identify earliest signs of Alzheimer's disease in mice

Alzheimer's disease wreaks emotional havoc on patients, who are robbed of their memories, their dignity, and their lives. It's financially devastating as well: care for Alzheimer's patients is predicted to top $1 trillion by about the time children born today are having children of their own.

5 Jan 2018

Study suggests vitamin C enhances tuberculosis drugs effectiveness

A new study conducted by researchers at the Albert Einstein College of Medicine, Bronx, NY, proposed the use of vitamin C together with tuberculosis drugs for rapid eradication of the disease-causing pathogens. The studies were carried out on mice and in tissue cultures and the results have been published in the journal of American Society for Microbiology, Antimicrobial Agents and Chemotherapy.

5 Jan 2018

Specific bacteria in the intestines can improve response rate to cancer immunotherapy

In the Jan. 5, 2018 issue of Science, researchers from the University of Chicago Medicine show that specific strains of commensal bacteria – the swarms of microorganisms naturally dwelling in the intestines – can improve the response rate to immunotherapy for patients being treated for advanced melanoma.

5 Jan 2018

UC Davis expert expresses caution on genetically engineered HSCs

In a commentary published in the Jan. 4 issue of the New England Journal of Medicine, UC Davis researcher William Murphy expressed cautious optimism about efforts to genetically engineer hematopoietic stem cells (HSCs) to temporarily resist cell death during transplantation.

4 Jan 2018

Soil-dwelling bacterium produces potential weapon against melanoma

A type of soil-dwelling bacterium produces molecules that induce death in melanoma cells, research at Oregon State University shows.

4 Jan 2018

New yardstick offers practical recommendations for treatment of atopic dermatitis

Patients with atopic dermatitis (AD) - also known as eczema - often face a tough, uphill battle for treatment. Symptoms include severe itching, scaly rashes, extreme dry skin and inflammation.

4 Jan 2018

Small-cell lung cancer patients encounter obstacles to receiving standard-of-care treatment

Despite decades of clinical research establishing chemotherapy with thoracic radiation as the standard-of-care for the initial management of non-metastatic small-cell lung cancer (SCLC), a large percentage of U.S. patients do not receive these treatments and in turn have lower overall survival, according to research from The University of Texas MD Anderson Cancer Center.

4 Jan 2018

Phase III clinical study of regenerative therapy for treating damaged cartilage has started

A group of researchers at Osaka University developed a synthetic tissue using synovium-derived mesenchymal stem cells (MSCs) for treating damaged cartilage, which had previously been incurable and had no effective therapies.

4 Jan 2018

LivaNova enrolls first patient in RESTORE-LIFE study for treatment-resistant depression

LivaNova PLC, a market-leading medical technology company, today announced the launch and enrollment of the first patient in the Global Prospective, Multi-center, Observational Post-market Study to Assess Short-, Mid- and Long-term Effectiveness and Efficiency of Vagus Nerve Stimulation Therapy® as Adjunctive Therapy in Real-world Patients with Difficult to Treat Depression.

4 Jan 2018

Study reveals a loophole in treatment of chronic lymphocytic leukemia

A team of researchers in Italy and Austria has determined that a drug approved to treat chronic lymphocytic leukemia (CLL) may be less effective in a particular subset of patients.

4 Jan 2018

Researchers develop new compound that inhibits growth of melanoma cells

An international team of researchers has developed a novel compound that successfully inhibits growth of melanoma cells by targeting specific epigenetic modifying proteins in these cells.

4 Jan 2018

Genetic labeling helps researchers track behavior of blood cells

By tagging bone marrow cells of mice with a genetic label, or barcode, researchers were able to track and describe the family tree of individual blood cells as they form in their natural environment.

4 Jan 2018

Supercomputers help scientists to devise cancer models for predicting individual treatment outcomes

Attempts to eradicate cancer are often compared to a "moonshot" -- the successful effort that sent the first astronauts to the moon.

3 Jan 2018

Study suggests potential means of stalling or even reversing diabetes-related blindness

Johns Hopkins researchers have discovered a cell signaling pathway in mice that triggers vision loss in patients with diabetic retinopathy and retinal vein occlusion – diseases characterized by the closure of blood vessels in the retina, leading to blindness.

3 Jan 2018

Study identifies exercises to help prevent chronic back pain in runners

A new study from The Ohio State University Wexner Medical Center examines what may cause chronic back pain in runners and the exercises to help prevent it.

3 Jan 2018

Researchers discover way to enhance effectiveness and safety of sonogenetics

Researchers at Duke University have discovered a way to enhance the effectiveness and safety of sonogenetics or ultrasonic modulation, emerging techniques that use sound waves to control the behavior of individual neurons or to promote tissue growth and wound healing in other cells.

3 Jan 2018

Spider's web inspires new device that could revolutionize management of type 1 diabetes

For the more than 1 million Americans who live with type 1 diabetes, daily insulin injections are literally a matter of life and death. And while there is no cure, a Cornell University-led research team has developed a device that could revolutionize management of the disease.

3 Jan 2018

New, sensitive screening test may allow clinicians to accurately detect Pompe disease

Researchers identified a new, more sensitive screening test to recognize Pompe disease, a metabolic disorder affecting cellular processing of glycogen in numerous tissues of the body.

2 Jan 2018

Rutgers researcher receives $1 million grant for international prostate cancer study

A $1 million grant from Gateway for Cancer Research will help Rutgers Cancer Institute of New Jersey Urologic Oncology Chief Isaac Yi Kim, MD, PhD, MBA evaluate the impact of surgically removing the prostate in men with metastatic prostate cancer in the United States and Asia.

2 Jan 2018

Therapy News and Research

Precision editing of gut bacteria reduces inflammation in mouse model of colitis

Researchers use Quest MRI to identify earliest signs of Alzheimer's disease in mice

Study suggests vitamin C enhances tuberculosis drugs effectiveness

Specific bacteria in the intestines can improve response rate to cancer immunotherapy

UC Davis expert expresses caution on genetically engineered HSCs

Soil-dwelling bacterium produces potential weapon against melanoma

New yardstick offers practical recommendations for treatment of atopic dermatitis

Small-cell lung cancer patients encounter obstacles to receiving standard-of-care treatment

Phase III clinical study of regenerative therapy for treating damaged cartilage has started

LivaNova enrolls first patient in RESTORE-LIFE study for treatment-resistant depression

Study reveals a loophole in treatment of chronic lymphocytic leukemia

Researchers develop new compound that inhibits growth of melanoma cells

Genetic labeling helps researchers track behavior of blood cells

Supercomputers help scientists to devise cancer models for predicting individual treatment outcomes

Study suggests potential means of stalling or even reversing diabetes-related blindness

Study identifies exercises to help prevent chronic back pain in runners

Researchers discover way to enhance effectiveness and safety of sonogenetics

Spider's web inspires new device that could revolutionize management of type 1 diabetes

New, sensitive screening test may allow clinicians to accurately detect Pompe disease

Rutgers researcher receives $1 million grant for international prostate cancer study

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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