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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

UAB researchers win grant to study metastasis of dead cancer cells

Researchers with the University of Alabama at Birmingham (UAB) Comprehensive Cancer Center and UAB Department of Chemistry have won an $805,000 grant from the U.S. Department of Defense Breast Cancer Research Program to study whether dead cancer cells left over after treatment encourage cancer's spread to other parts of the body.

11 Jun 2010

Ion Torrent extends Ion PGM Sequencer Grant Program to Europe

Ion Torrent today announced that it is extending its Ion PGM Sequencer Grant Program to Europe, and will award two sequencers to scientists there in the second half of 2010. This spring Ion Torrent received hundreds of grant proposals from scientists in North America, and in April two winners were each awarded an Ion PGM sequencer.

11 Jun 2010

Pfizer to join SGC-led collaboration to generate chemical probes for proteins involved in epigenetic signalling

The Structural Genomics Consortium (SGC) and Pfizer today announced that Pfizer will join the SGC-led public-private collaboration to generate small molecule inhibitors - "chemical probes" - for proteins involved in epigenetic signalling.

11 Jun 2010

Study identifies mechanism that interrupts normal p53 gene function leading to tumor development

The p53 gene has been a well-documented player in the prevention of tumors. It is considered the most frequently mutated gene in human tumors with more than half harboring p53 mutations (Bennett et al., 1999). These mutations often can be caused by disruption in normal p53 function.

11 Jun 2010

WaferGen announces microRNA, oncology gene panels for SmartChip Real-Time PCR System

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genetic analysis systems, today announced the availability of two gene expression profiling panels for the SmartChip Real-Time PCR System that will enable microRNA and cancer pathway profiling capability.

10 Jun 2010

NanoString Technologies launches new solution to detect CNVs in human genomic samples

NanoString Technologies, Inc., a privately held life sciences company marketing a complete solution for detecting and counting large sets of target molecules in biological samples, today announced the launch of its early access program for a unique new solution that detects copy number variation in human genomic samples. The program was announced in conjunction with the company's participation in the European Human Genetics Conference in Gothenburg, Sweden.

From NanoString Technologies 10 Jun 2010

Researchers validate effectiveness of genome sequencing process for hereditary genetic diseases

A research team led by Dr. Nada Jabado at the MUHC Research Institute and Dr. Jacek Majewski at McGill University has proven for the first time that it is possible to identify any genetic disease in record time thanks to a powerful and reliable exome sequencing method. The exome, a small part of the genome ((less than) 2%), is of crucial interest with regard to research on genetic diseases as it accounts for 85% of mutations.

10 Jun 2010

Study to understand process of telomere shortening

A new study at the University of Leicester is examining a sequence of DNA- known as telomeres - that varies in length between individual.

10 Jun 2010

Study suggests potential of ARC man-made compound in combination with Abbott's ABT-737 for cancer

Adding a second agent may make a new, experimental anti-cancer drug effective against a wide range of cancers, researchers at the University of Illinois at Chicago College of Medicine have found.

10 Jun 2010

Copy number variants may cause autism: Study

An international consortium of researchers from more than 70 universities, including the University of Utah, has reported that a study of nearly 2,300 people supports the growing consensus that autism is caused in part by rare genetic changes called copy number variants (CNVs).

10 Jun 2010

World's largest DNA scan reveals new genetic changes in autistic children

The world's largest DNA scan for familial autism has uncovered new genetic changes in autistic children that are often not present in their parents. Identified in less than 1 percent of the population, these rare variants occur nearly 20 percent more in autistic children.

10 Jun 2010

Argus Optical Mapping System for microbial whole genome analysis launched at ASM 2010 General Meeting

OpGen, Inc., a microbial genomics solutions company, announced the launch of the Argus Optical Mapping System for microbial whole genome analysis at the ASM 2010 General Meeting held in San Diego, CA May 23-27, 2010. The Argus Optical Mapping System is based on Optical Mapping Technology which generates ordered, whole genome restriction maps from single DNA molecules.

10 Jun 2010

FDA approves Roxane Laboratories' Valacyclovir Hydrochloride Tablets ANDA

Roxane Laboratories, Inc. announced today the Abbreviated New Drug Application (ANDA) approval of Valacyclovir Hydrochloride Tablets 500mg and

10 Jun 2010

Combination therapy appears to improve outcome of women with late-stage ovarian cancer

The combination of decitabine and carboplatin appears to improve the outcome of women who have late-stage ovarian cancer. In an upcoming issue of the journal Cancer (online today), Indiana University researchers report four of 10 patients who participated in a phase I clinical trial had no disease progression after six months of treatment. One patient experienced complete resolution of tumor tissue for a period of time.

10 Jun 2010

SFDA approves China Medical Technologies' SPR-based HPV-DNA chip

China Medical Technologies, Inc., a leading China-based advanced in-vitro diagnostic company, today announced that it has received approval for its SPR-based HPV-DNA chip from the State Food and Drug Administration of China (the "SFDA").

10 Jun 2010

Autism is caused in part by CNVs: Study

10 Jun 2010

CGH, FISH techniques effective for postmortem analysis of fetuses, infants with congenital anomalies

New techniques to detect chromosomal abnormalities can offer a higher degree of accuracy. Chromosomal abnormalities are a well-known cause of multiple congenital anomalies, and conventional methods of culture analysis have proven unsuccessful in 10% to 40% of cases. Comparative genomic hybridization (CGH) and fluorescent in situ hybridization (FISH) techniques were tested and found successful by analyzing tissue from children who had multiple congenital anomalies.

9 Jun 2010

RCSI scientists make breakthrough in understanding human adaptation to high altitude environments

A group of top international scientists including geneticists from the Royal College of Surgeons in Ireland has made a breakthrough in understanding human adaptation to high altitude environments.

9 Jun 2010

Purdue University researchers develop potential new tool for medical diagnostics, testing food

Researchers at Purdue University have developed a potential new tool for medical diagnostics, testing food and water for contamination, and crime-scene forensics.

9 Jun 2010

Multiple presentations on nab-driven chemotherapy at 46th ASCO

Abraxis BioScience, Inc. presented abstracts describing 10 trials of nanoparticle albumin bound (nab®) driven chemotherapy, nab-paclitaxel (ABRAXANE® for Injectable Suspension; paclitaxel albumin protein-bound particles for injectable suspension), for the treatment of breast cancer at the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

9 Jun 2010

DNA News and Research

Further Reading

UAB researchers win grant to study metastasis of dead cancer cells

Ion Torrent extends Ion PGM Sequencer Grant Program to Europe

Pfizer to join SGC-led collaboration to generate chemical probes for proteins involved in epigenetic signalling

Study identifies mechanism that interrupts normal p53 gene function leading to tumor development

WaferGen announces microRNA, oncology gene panels for SmartChip Real-Time PCR System

NanoString Technologies launches new solution to detect CNVs in human genomic samples

Researchers validate effectiveness of genome sequencing process for hereditary genetic diseases

Study to understand process of telomere shortening

Study suggests potential of ARC man-made compound in combination with Abbott's ABT-737 for cancer

Copy number variants may cause autism: Study

World's largest DNA scan reveals new genetic changes in autistic children

Argus Optical Mapping System for microbial whole genome analysis launched at ASM 2010 General Meeting

FDA approves Roxane Laboratories' Valacyclovir Hydrochloride Tablets ANDA

Combination therapy appears to improve outcome of women with late-stage ovarian cancer

SFDA approves China Medical Technologies' SPR-based HPV-DNA chip

Autism is caused in part by CNVs: Study

CGH, FISH techniques effective for postmortem analysis of fetuses, infants with congenital anomalies

RCSI scientists make breakthrough in understanding human adaptation to high altitude environments

Purdue University researchers develop potential new tool for medical diagnostics, testing food

Multiple presentations on nab-driven chemotherapy at 46th ASCO

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