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CX3CL1 signaling chemical can offer better understanding of Parkinson's disease

Targeting the neuroinflammatory causes of Parkinson's disease with a naturally present brain chemical signal could offer a better understanding of the clinical mechanisms of the disease and open a future therapeutic window, reports a team of researchers from the University of South Florida Department Neurosurgery and Brain Repair and the James A. Haley Veterans' Administration Hospital, Tampa.

14 Feb 2011

Some fat is essential for body function

It's common knowledge that too much cholesterol and other fats can lead to disease, and that a healthy diet involves watching how much fatty food we eat. However, our bodies need a certain amount of fat to function—and we can't make it from scratch.

14 Feb 2011

New study on mosquito genome sequences to identify 'transposable elements'

A team of scientists at the University of California, Riverside has begun working on a mosquito research project that, if successful, will provide valuable genetic resources capable of transforming the way mosquito research is conducted around the world.

14 Feb 2011

First evidence of human DNA fragment in bacterial genome

If a human cell and a bacterial cell met at a speed-dating event, they would never be expected to exchange phone numbers, much less genetic material. In more scientific terms, a direct transfer of DNA has never been recorded from humans to bacteria.

14 Feb 2011

U.S. FDA clears QMS Everolimus Immunoassay to prevent rejection in kidney transplants

The U.S. Food and Drug Administration today announced that it has cleared a test to help manage potential organ rejection in kidney transplant patients. The test, called QMS Everolimus Immunoassay, monitors the blood level of everolimus, a drug that helps prevent rejection in kidney transplants.

14 Feb 2011

Gene-transfer system may control mosquito-borne diseases without pesticides

Scientists have modeled a system that may be used to control mosquitoes and the diseases they transmit, without the use of pesticides. In the proposed system, mosquitoes are engineered to carry two genes. The first gene causes males to transmit a toxin to females through their semen. The second gene, when expressed in females, makes them immune to this toxin.

14 Feb 2011

Study finds LC damage and reduction in noradrenaline levels in brain are linked with MS

Researchers at the University of Illinois at Chicago have shown for the first time that damage to a particular area of the brain and a consequent reduction in noradrenaline are associated with multiple sclerosis.

13 Feb 2011

HIV infection in mothers reduces disease resistance in babies: Study

New research suggests that babies whose mothers have HIV, but are not HIV-infected themselves, are born with lower levels of specific proteins in their blood called antibodies, which fight infection, compared with babies not exposed to HIV.

13 Feb 2011

Protective immunity against HIV can be achieved without presence of virus neutralizing antibodies in the blood

New research shows that protective immunity against HIV can be achieved without the presence of virus neutralizing antibodies in the blood. The study, published by Cell Press in the February issue of the journal Immunity, demonstrates that a vaccine which stimulates production of specific anti-HIV antibodies in the vaginal tissue was sufficient to protect monkeys from exposure to live virus.

11 Feb 2011

Vaccinating through salivary glands may provide protection against wide range of diseases

If you don't like shots or needles, you're in luck. New research published online in The FASEB Journal gives the development of new oral vaccinations a shot in the arm thanks to discoveries involving the salivary glands of mice. In addition, this research report also offers a tantalizing glimpse of vaccines that could prevent infection at mucosal surfaces, even if direct injections into the body fail to cause immunity. This technique may be effective for a wide range of diseases from influenza to cholera.

11 Feb 2011

Blocking interleukin 15 may help restore oral tolerance to gluten

Blocking a factor that can activate the human immune response against intestinal bacteria or certain foods could prevent the development of celiac disease in those most at risk, researchers report in the journal Nature.

11 Feb 2011

Study reveals beneficial anti-fibrotic effects of Pentraxin-2 in TGFβ1-induced lung disease

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, announced today the publication of collaborative research in the International Journal of Biochemistry and Cell Biology entitled, "TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P."

11 Feb 2011

RF-induced heat therapy could help treat common parasitic skin infection

Scientists are hoping that heat therapy could eventually replace a complex drug regimen as the first-line treatment of a parasitic skin infection common in tropical and subtropical regions of the world.

11 Feb 2011

Richard J. Fasenmyer Foundation awards $3M to Cleveland physicians for AIDS research

A three-year, $3 million gift from the Richard J. Fasenmyer Foundation will fund research by a pair of Cleveland physicians into HIV and the body's response in autoimmune diseases.

11 Feb 2011

Viral infection of Leishmania leads to increased pathogenicity

A parasite and a virus may be teaming up in a way that increases the parasite's ability to harm humans, scientists at the University of Lausanne in Switzerland and Washington University School of Medicine in St. Louis report this week in Science.

11 Feb 2011

Study finds too low drug concentrations used for treatment of children with TB

The realization of medically treating different children uniquely may start with one of the deadliest diseases in existence: tuberculosis.

11 Feb 2011

Promedior initiates Phase 1b clinical study of PRM-151 in patients with IPF

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, announced today that it has initiated a Phase 1b clinical study of PRM-151 to explore the safety, tolerability, pharmacokinetics, and phamacodynamics of PRM-151 in the treatment of patients with idiopathic pulmonary fibrosis.

11 Feb 2011

Avian flu vaccine stockpiled in 2004 still useful

A stockpiled vaccine designed to fight a strain of avian flu that circulated in 2004 can be combined with a vaccine that matches the current strain of bird flu to protect against a potential pandemic, researchers from Saint Louis University's Center for Vaccine Development have found.

10 Feb 2011

First patient treated in cytomegalovirus~ACE/ASPECT Phase II randomised clinical trial

Cell Medica, a leading UK cellular therapeutics company that develops, manufactures and markets cellular immunotherapy products for the treatment of infectious disease and cancer, announces today that the first patient has been treated in the CMV~ACE/ASPECT trial at University College Hospital London.

10 Feb 2011

NIAID doctor receives Will Rogers Institute's award for outstanding contributions to lung research

The Will Rogers Institute's annual prize for outstanding contributions to lung research has been awarded to Dr. Anthony Fauci. The $50,000 award was created to honor individuals for extraordinary work leading to advancements in treatment for lung diseases. He is the fourth recipient of the prestigious prize from the Will Rogers Institute.

10 Feb 2011

Immune System News and Research

CX3CL1 signaling chemical can offer better understanding of Parkinson's disease

Some fat is essential for body function

New study on mosquito genome sequences to identify 'transposable elements'

First evidence of human DNA fragment in bacterial genome

U.S. FDA clears QMS Everolimus Immunoassay to prevent rejection in kidney transplants

Gene-transfer system may control mosquito-borne diseases without pesticides

Study finds LC damage and reduction in noradrenaline levels in brain are linked with MS

HIV infection in mothers reduces disease resistance in babies: Study

Protective immunity against HIV can be achieved without presence of virus neutralizing antibodies in the blood

Vaccinating through salivary glands may provide protection against wide range of diseases

Blocking interleukin 15 may help restore oral tolerance to gluten

Study reveals beneficial anti-fibrotic effects of Pentraxin-2 in TGFβ1-induced lung disease

RF-induced heat therapy could help treat common parasitic skin infection

Richard J. Fasenmyer Foundation awards $3M to Cleveland physicians for AIDS research

Viral infection of Leishmania leads to increased pathogenicity

Study finds too low drug concentrations used for treatment of children with TB

Promedior initiates Phase 1b clinical study of PRM-151 in patients with IPF

Avian flu vaccine stockpiled in 2004 still useful

First patient treated in cytomegalovirus~ACE/ASPECT Phase II randomised clinical trial

NIAID doctor receives Will Rogers Institute's award for outstanding contributions to lung research

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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