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New trial confirms superiority of triplet regimen over standard care in resectable esophago-gastric cancer

The superiority of docetaxel based triplet therapy over standard care in patients with resectable oesophago-gastric cancer has been confirmed in late-breaking results from the FLOT4 trial presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Internet-based IRT may be effective treatment to improve nightmare distress

Nightmares are extremely dysphoric dreams, which are prevalent and associated with psychological strain. This study investigated (a) the efficacy of an internet-based imagery rehearsal therapy (IRT), (b) the role of imagery rescription, and (c) the role of guidance during internet-based IRT.

8 Sep 2017

Self-help preventive cognitive therapy found to be effective in reducing recurrent depression

In the current issue of Psychotherapy and Psychosomatic a Group of Dutch investigators reports on the findings of a randomized controlled trial on the role of self-help in depression.

8 Sep 2017

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

Adding taselisib to letrozole before surgery significantly improved outcomes for patients with early breast cancer that was both estrogen receptor positive and HER2-negative (ER+/HER2-) according to results of the LORELEI trial, presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

For low-income drug users, Medi-Cal offers a fresh start

Breann Johnson stopped using heroin on Mother's Day this year, determined to end her 13-year addiction. Days later, she began three months of residential treatment in Riverside, Calif. — all paid for by California's Medicaid program.

8 Sep 2017

SleepRate introduces new campaign to solve global sleep crisis

SleepRate, the developer of a comprehensive sleep improvement app, today announces the launch of the ‘Global Sleep Fix’ event, which will run between 5th September and 3rd October.

8 Sep 2017

CGT Catapult partners with TrakCel to incorporate tracking technology into cell and gene therapy manufacturing centre

The Cell and Gene Therapy Catapult (CGT Catapult) today announces a partnership agreement with UK-headquartered company TrakCel to incorporate its needle-to-needle supply chain management platform into the CGT Catapult’s large-scale cell and gene therapy manufacturing centre.

8 Sep 2017

Direct-acting antiviral therapy found to be safe, effective in patients with CKD and HCV infection

A new study indicates that direct-acting antiviral therapy is safe and effective in patients with chronic kidney disease (CKD) and Hepatitis C virus (HCV) infection.

8 Sep 2017

Combination treatment provides positive results for people with advanced melanoma

In a two-year UCLA-led study, nearly two-thirds of people with advanced melanoma responded positively to a treatment that combines the immunotherapy drug pembrolizumab with a herpes virus called talimogene laherpareovec, or T-VEC.

8 Sep 2017

New drug treatment linked to higher bladder compliance after spinal cord injury

Researchers have shown that compared to placebo, a drug treatment intended to prevent remodeling of the bladder wall and given within 48 hours after spinal cord injury (SCI) in dogs was associated with significantly higher bladder compliance.

7 Sep 2017

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Researchers from the Perelman School of Medicine at the University of Pennsylvania have made a discovery about muscular dystrophy disorders that suggest new possibilities for treatment.

7 Sep 2017

Generic drug used to increase blood flow may improve effectiveness of cancer immunotherapy

Cancer immunotherapy drugs only work for a minority of patients, but a generic drug now used to increase blood flow may be able to improve those odds, a study by Columbia University Medical Center researchers suggests.

7 Sep 2017

Researchers reveal new approach to precisely identify and treat prostate cancer

Researchers have demonstrated a new, effective way to precisely identify and localize prostate cancer tumors while protecting healthy tissue and reducing side effects.

7 Sep 2017

New human stem cell model could pave way for macular degeneration research

Macular degeneration is the leading cause of vision loss in older adults, but scientists have long struggled to study and replicate key elements of the disease in the lab.

7 Sep 2017

Researchers define how cancer drug works in cells, mice and man

Science is very good at determining how drugs work in experimental models. New research out of Dartmouth's Norris Cotton Cancer Center led by Alan Eastman, PhD, helps to bridge the gap when it comes to ensuring that drugs work by the same mechanism in human patients.

7 Sep 2017

New microfluidic device offers insights on cancer metastasis

As cancer grows, it evolves. Individual cells become more aggressive and break away to flow through the body and spread to distant areas.

7 Sep 2017

TUM scientists pave way for better diagnosis of motor deficits following stroke

After a stroke, many people are unable to successfully perform basic hand movements in everyday life. The reason are symptoms of hemiparesis resulting from damage to the brain.

7 Sep 2017

Researchers find signaling pathway in cells that plays key role in development of fatty liver disease

Morbid obesity affects the liver: Almost one-third of all adults suffer from chronic fatty liver disease, which can lead to infections and even trigger cancer. Researchers at the University Children's Hospital Zurich and the University of Zurich have now found a signaling pathway in cells that play an important role in the development of fatty liver disease.

7 Sep 2017

Study describes link between key melanoma signaling pathway and novel class of drugs

Results of a study by The Wistar Institute have described a correlation between a key melanoma signaling pathway and a novel class of drugs being tested in the clinic as adjuvant therapy for advanced melanoma, providing useful information for a more effective use of this type of treatment.

7 Sep 2017

Exploration of human genetics reveals new targets to combat heart disease

Again and again, it's the rare among humans that help the rest of us. The exploration of human genetics is revealing new targets to combat heart disease among atypical variants. Mutations in genes that play a role in heart health are the inspiration for a cluster of new heart drugs.

7 Sep 2017

Therapy News and Research

New trial confirms superiority of triplet regimen over standard care in resectable esophago-gastric cancer

Internet-based IRT may be effective treatment to improve nightmare distress

Self-help preventive cognitive therapy found to be effective in reducing recurrent depression

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

For low-income drug users, Medi-Cal offers a fresh start

SleepRate introduces new campaign to solve global sleep crisis

CGT Catapult partners with TrakCel to incorporate tracking technology into cell and gene therapy manufacturing centre

Direct-acting antiviral therapy found to be safe, effective in patients with CKD and HCV infection

Combination treatment provides positive results for people with advanced melanoma

New drug treatment linked to higher bladder compliance after spinal cord injury

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Generic drug used to increase blood flow may improve effectiveness of cancer immunotherapy

Researchers reveal new approach to precisely identify and treat prostate cancer

New human stem cell model could pave way for macular degeneration research

Researchers define how cancer drug works in cells, mice and man

New microfluidic device offers insights on cancer metastasis

TUM scientists pave way for better diagnosis of motor deficits following stroke

Researchers find signaling pathway in cells that plays key role in development of fatty liver disease

Study describes link between key melanoma signaling pathway and novel class of drugs

Exploration of human genetics reveals new targets to combat heart disease

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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