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Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Researchers have been examining the pathology and spread of the Omicron variant in mink.

18 Feb 2022

Ensitrelvir, a novel SARS-CoV-2 antiviral

S-217622 reduces the viral load and help alleviate the severity of SARS-CoV-2 in infected hamsters.

17 Feb 2022

Study explores differential immune responses against SARS-CoV-2 in adults and children

A new study revealed that the immune responses against SARS-CoV-2 and the clinical course of COVID-19 differs between children and adults.

17 Feb 2022

mRNA COVID-19 vaccine shown to induce afucosylated antibodies in individuals without prior SARS-CoV-2 exposure

New study findings reveal that the level of afucosylated anti-spike antibodies increases transiently in infection-naïve individuals after the first COVID-19 vaccine dose.

17 Feb 2022

Frequency and function of SARS-CoV-2-specific T cells in individuals with pulmonary PASC

Researchers examined patients with pulmonary PASC of SARS-CoV-2 to determine the frequency and function of SARS-CoV-2-specific T cells in their blood.

17 Feb 2022

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

A new study discusses the state of current knowledge about the potential use of tea polyphenols in the prevention and treatment of COVID-19.

16 Feb 2022

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

Researchers investigate SARS-CoV-2 mutations present across the whole genome of different SARS-CoV-2 variants.

15 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from Toronto, Canada, characterized the markers of endothelial function and developed micro ribonucleic acid (miRNA) expression atlas in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive and -negative patients admitted to the intensive care unit (ICU).

15 Feb 2022

Group cell movement could be harnessed to stop cancer spread, study suggests

Cells push and pull on surrounding tissue to move in groups as they form organs in an embryo, track down invading bacteria, and become cancerous and spread.

14 Feb 2022

First survey on Omicron BA.2 in France

In a recent study posted to the medRxiv* preprint server, researchers described the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 21L/BA.2 Omicron variant in south-eastern France.

14 Feb 2022

Structural protein vimentin facilitates SARS-CoV-2 entry into endothelial cells

Researchers suggest that extracellular vimentin may act as a coreceptor to allow for SARS-CoV-2 entry into cells.

14 Feb 2022

Hyperactive microglia can have a protective effect in the course of neurodegenerative diseases

Findings by researchers from Germany support the view that hyperactive immune cells in the brain can have a protective effect in the course of neurodegenerative diseases.

14 Feb 2022

Hundreds of new proteins that could play a role in cystic fibrosis discovered

Researchers at the University of Toronto have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.

14 Feb 2022

Study reveals that 1PBC and niclosamide bind the same drug-binding pocket

Researchers used cryo-EM to demonstrate that 1PBC, and the drug niclosamide, both inhibitors of TMEM16 proteins, have therapeutic potential and may be used for COVID-19 treatment.

14 Feb 2022

An alternative strategy targeting furin disrupts SARS-CoV-2 infection cycle

A new study was based on the hypothesis that competitively inhibiting cellular furin and selectively targeting SARS-CoV-2 in the infected viral-producing cells is critical for therapeutic specificity.

14 Feb 2022

Researchers identify autoantibody targets in COVID-19 patients

In a new study, researchers have been investigating auto-immune responses to natural human antigens in COVID-19 patients.

14 Feb 2022

Testes found to be a viral reservoir for SARS-CoV-2 replication

In a recent study posted to the medRxiv* pre-print server, researchers used a suite of methods to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the testis of patients who died from coronavirus disease 2019 (COVID-19) to gain insights into SARS-CoV-2 tropism inside testis and its impact on male fertility.

13 Feb 2022

SARS-CoV-2 nucleocapsid G215C variation may explain Delta severity

A new study shows that the SARS-CoV-2 nucleocapsid protein has unique properties that allow the virus to become more infective in the presence of certain mutations.

11 Feb 2022

Screening assays identify TMPRSS2 inhibitors from drug repurposing candidates useful as COVID-19 therapeutic

Researchers used an assay toolset for discovering new transmembrane protease serine 2 inhibiting drug repurposing candidates, that can be useful as therapeutics for COVID-19 treatment.

10 Feb 2022

Membrane News and Research

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Ensitrelvir, a novel SARS-CoV-2 antiviral

Study explores differential immune responses against SARS-CoV-2 in adults and children

mRNA COVID-19 vaccine shown to induce afucosylated antibodies in individuals without prior SARS-CoV-2 exposure

Frequency and function of SARS-CoV-2-specific T cells in individuals with pulmonary PASC

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

Group cell movement could be harnessed to stop cancer spread, study suggests

First survey on Omicron BA.2 in France

Structural protein vimentin facilitates SARS-CoV-2 entry into endothelial cells

Hyperactive microglia can have a protective effect in the course of neurodegenerative diseases

Hundreds of new proteins that could play a role in cystic fibrosis discovered

Study reveals that 1PBC and niclosamide bind the same drug-binding pocket

An alternative strategy targeting furin disrupts SARS-CoV-2 infection cycle

Researchers identify autoantibody targets in COVID-19 patients

Testes found to be a viral reservoir for SARS-CoV-2 replication

SARS-CoV-2 nucleocapsid G215C variation may explain Delta severity

Screening assays identify TMPRSS2 inhibitors from drug repurposing candidates useful as COVID-19 therapeutic

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