Mouse Model News and Research

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Alarmins are the 'gold' in breast milk

Breast milk strengthens a child's immune system, supporting the intestinal flora. These facts are common knowledge.

28 Aug 2020

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Alberto Yáñez Boyer, Ramón y Cajal researcher at BIOTECMED (Interdisciplinary Research Structure in Biotechnology and Biomedicine) and the Department of Microbiology and Ecology at the University of Valencia (UV), participates in a study on the C9orf72 gene and its mutations in the immune system.

28 Aug 2020

Mouse-adapted SARS-CoV-2 model helps advance the development of COVID-19 vaccines

A new COVID-19 mouse model developed at the University of North Carolina at Chapel Hill captures many of the features of human disease and has helped advance a COVID-19 vaccine candidate to clinical trial.

27 Aug 2020

First lethal mouse model of SARS-CoV-2 developed

Army scientists have developed the first lethal mouse model of SARS-CoV-2, the virus that causes COVID-19, using mice that were genetically engineered to express the human ACE2 gene--a key mechanism by which the virus enters human cells.

27 Aug 2020

New approach to combination drug design could be applied to disease therapies beyond diabetes

Biomedical engineers at Duke University have shown that the efficacy of a two-pronged type 2 diabetes treatment increases when the drugs are linked by a heat-sensitive tether rather than simply concurrently administered.

27 Aug 2020

Study: Blocking nerve signals to the pancreas could stop patients from developing type 1 diabetes

Your pancreas is a little sweet potato-shaped organ that sits snug behind your stomach. The pancreas is studded with islets, the cell clusters that house insulin-producing beta cells.

27 Aug 2020

Consuming personal fecal microbiome when dieting may limit weight regain, study shows

People who consume frozen microbiome capsules derived from their own feces when dieting may limit their weight regain, according to a new study published in Gastroenterology, conducted by a team of researchers led by researchers at Ben-Gurion University of the Negev.

26 Aug 2020

New approach provides a roadmap for linking neurological and locomotor deficits

Locomotion deficits, such as lack of coordination, a shuffling gait, or loss of balance, can result from neurological conditions, specifically those that affect motor areas of the nervous system.

24 Aug 2020

Researchers identify potential drug target for curtailing cancer metastasis

Researchers led by Ludwig Chicago Co-director Ralph Weichselbaum and Ronald Rock of the University of Chicago have identified in preclinical studies a potential drug target for curtailing cancer metastasis.

24 Aug 2020

Researchers find a new way to slow colon cancer metastasis

When cancer metastasizes and spreads throughout the body, it can severely change the prognosis of the disease. It is estimated that metastasis is responsible for 90 percent of cancer deaths.

24 Aug 2020

Study reveals a promising method for treating multiple sclerosis

A research team led by neurobiologist Professor Claire Jacob has identified an important mechanism that can be used to control the restoration of myelin sheaths following traumatic injury and in degenerative diseases.

24 Aug 2020

A metabolic enzyme shows great potential as target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

20 Aug 2020

Air pollution may play a role in development of cardiometabolic diseases, shows study

Air pollution is the world's leading environmental risk factor, and causes more than nine million deaths per year.

20 Aug 2020

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

ETH Zurich scientists have developed an RNA molecule that can be used in bone marrow cells to correct genetic errors that affect protein production.

18 Aug 2020

Gene editing approach removes oral herpes

Infectious disease researchers at Fred Hutchinson Cancer Research Center have used a gene editing approach to remove latent herpes simplex virus 1, or HSV-1, also known as oral herpes.

18 Aug 2020

Researchers identify new therapeutic target for Alzheimer's disease

Scientists at St. Jude Children's Research Hospital are advancing understanding of a potential Alzheimer's disease treatment.

18 Aug 2020

New treatment approach strengthens motor function and muscle of aged mice

In an aging society, one of the most important and urgent tasks of scientific research is to counteract the decline in motor function and muscle weakness that accompanies the aging process.

17 Aug 2020

Nanoparticle carriers expand the effectiveness of gene therapies for human eye diseases

NIBIB-funded researchers have created nanoparticles for successful gene therapy of a mouse model of macular degeneration.

15 Aug 2020

Study identifies new set of multi-tasking taste cells

Our mouths may be home to a newly discovered set of multi-tasking taste cells that - unlike most known taste cells, which detect individual tastes - are capable of detecting sour, sweet, bitter and umami stimuli.

13 Aug 2020

New cell injection technique could help reverse forms of vision loss

University of Toronto Engineering researchers have developed a new method of injecting healthy cells into damaged eyes.

13 Aug 2020

Mouse Model News and Research

Alarmins are the 'gold' in breast milk

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Mouse-adapted SARS-CoV-2 model helps advance the development of COVID-19 vaccines

First lethal mouse model of SARS-CoV-2 developed

New approach to combination drug design could be applied to disease therapies beyond diabetes

Study: Blocking nerve signals to the pancreas could stop patients from developing type 1 diabetes

Consuming personal fecal microbiome when dieting may limit weight regain, study shows

New approach provides a roadmap for linking neurological and locomotor deficits

Researchers identify potential drug target for curtailing cancer metastasis

Researchers find a new way to slow colon cancer metastasis

Study reveals a promising method for treating multiple sclerosis

A metabolic enzyme shows great potential as target for immunotherapies

Air pollution may play a role in development of cardiometabolic diseases, shows study

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

Gene editing approach removes oral herpes

Researchers identify new therapeutic target for Alzheimer's disease

New treatment approach strengthens motor function and muscle of aged mice

Nanoparticle carriers expand the effectiveness of gene therapies for human eye diseases

Study identifies new set of multi-tasking taste cells

New cell injection technique could help reverse forms of vision loss

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