Preclinical News and Research

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Menthol inhalation improves cognitive ability in animal models of Alzheimer's disease

Researchers from Cima University of Navarra (Spain) have shown in animal models of Alzheimer's disease that inhaling menthol improves cognitive ability.

10 May 2023

Launching Revvity: A Scientific Solutions Company Powering Innovation from Discovery to Cure

Transformation aimed at revolutionizing next generation scientific breakthroughs that solve the world’s greatest health challenges

From Revvity 9 May 2023

Researchers evaluate the dual-therapeutic effect of gene therapy in mouse model of osteosarcoma

Investigators at Brigham and Women’s Hospital and collaborating institutions evaluated the dual-therapeutic effect of gene therapy in a clinically relevant model for common form of bone cancer.

8 May 2023

First CRISPR-armed phage therapeutic can specifically target and remove E. coli in the human gut

SNIPR Biome ApS ("SNIPR"), the company pioneering CRISPR-based microbial gene therapy, announces today that Nature Biotechnology has published research findings from its preclinical work on SNIPR001, the first CRISPR-armed phage therapeutic developed to specifically target and remove E. coli, including antibiotic-resistant strains, in the human gastrointestinal tract.

8 May 2023

The safety and efficacy of FINLAY-FR-2/1A, a new protein-based COVID-19 vaccine

Research paper reports the results of a phase 3 clinical trial evaluating the efficacy and safety of the FINLAY-FR-2 and FINLAY-FR-1A vaccines in Iranian adults.

7 May 2023

Gyros Protein Technologies introduces Gyrolab Generic Cyno ADA Kit Reagents to support pre-clinical immunogenicity assessment

Gyros Protein Technologies AB, a leading provider of peptide synthesizers and reagents and a pioneer in automated nanoliter-scale immunoassays, today announced the introduction of Gyrolab® Generic Cyno Anti-Drug Antibodies (ADA) Kit Reagents, for the detection of circulating immune complexes of human IgG with cyno anti-human IgG.

From Gyros Protein Technologies AB 4 May 2023

Using MRI for earlier detection of chronic kidney disease

Chronic Kidney Disease (CKD) is a major public health challenge affecting more than 10% of people. A key challenge for effective treatment is early identification of patients that are at risk of CKD to ensure timely intervention.

3 May 2023

Researchers report positive results from Phase 2 clinical trial of investigational treatment against long COVID fatigue

Researchers from the University of Oxford have reported findings from a Phase 2 clinical trial investigating the efficacy of an investigational treatment against long COVID fatigue.

3 May 2023

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform."

3 May 2023

Light or moderate exercise can improve the prognosis of cancer

Two new Finnish studies show that short bouts of light or moderate exercise can increase the number of immune cells in the bloodstream of cancer patients.

2 May 2023

FAU and Insightec collaborate to use focused ultrasound to treat brain diseases

During his trade mission trip to Israel, Florida Gov. Ron DeSantis announced a new agreement between Florida Atlantic University and Insightec, a global health care company headquartered in Haifa, Israel.

2 May 2023

Researchers develop novel bio-inspired molecules to enhance bone regeneration

People's ability to regenerate bones declines with age and is further decreased by diseases such as osteoporosis.

28 Apr 2023

Insomnia drug shows potential as an effective treatment for opioid use disorder

The insomnia drug suvorexant (Belsomra) might be an effective treatment for opioid use disorder, according to a preclinical study from Scripps Research.

27 Apr 2023

Research identifies Th1 memory CD4+ T cells as key to protect against emerging poxvirus skin infections

Researchers demonstrate that T helper 1 effector memory cluster of differentiation 4 T cells provide immunity against poxviruses

27 Apr 2023

Groundbreaking discovery could pave the way for safer and more effective blood thinners

Safer and more effective blood thinners could be on the way following a groundbreaking discovery by researchers at UBC and the University of Michigan, published today in Nature Communications.

26 Apr 2023

New approach to CAR T-cell therapy shows promise against small cell lung cancer in preclinical study

A new approach to chimeric antigen receptor T-cell (CAR T) therapy has shown great promise against small cell lung cancer (SCLC) in a preclinical study.

25 Apr 2023

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

Targeting part of an antiviral pathway triggered by the accumulation of a key pathogen shared in Alzheimer's disease and frontotemporal dementia may one day offer a new therapeutic approach to deterring or delaying cognitive decline, according to preclinical research led by Weill Cornell Medicine scientists.

24 Apr 2023

Preclinical News and Research

Menthol inhalation improves cognitive ability in animal models of Alzheimer's disease

Launching Revvity: A Scientific Solutions Company Powering Innovation from Discovery to Cure

Researchers evaluate the dual-therapeutic effect of gene therapy in mouse model of osteosarcoma

First CRISPR-armed phage therapeutic can specifically target and remove E. coli in the human gut

The safety and efficacy of FINLAY-FR-2/1A, a new protein-based COVID-19 vaccine

Gyros Protein Technologies introduces Gyrolab Generic Cyno ADA Kit Reagents to support pre-clinical immunogenicity assessment

Using MRI for earlier detection of chronic kidney disease

Researchers report positive results from Phase 2 clinical trial of investigational treatment against long COVID fatigue

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

Light or moderate exercise can improve the prognosis of cancer

FAU and Insightec collaborate to use focused ultrasound to treat brain diseases

Researchers develop novel bio-inspired molecules to enhance bone regeneration

Insomnia drug shows potential as an effective treatment for opioid use disorder

Research identifies Th1 memory CD4+ T cells as key to protect against emerging poxvirus skin infections

Groundbreaking discovery could pave the way for safer and more effective blood thinners

New approach to CAR T-cell therapy shows promise against small cell lung cancer in preclinical study

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

Mitophagy helps blood cancer cells to evade the killing effects of BH3 mimetic drug

Researchers develop a backpack-based myeloid cell therapy for MS patients

How alcohol intake contributes to increased pain and hypersensitivity

Event guide: 4th LNP Formulation & Process Development Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics