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New partnership launches marketplace to revive deprioritized cell and gene therapies

The American Society of Gene & Cell Therapy (ASGCT), the leading professional organization for the advancement of cell and gene therapies (CGTs), and the Orphan Therapeutics Accelerator (OTXL), a non-profit biotech focused on completing development and enabling access to stalled rare disease treatments, today announced a partnership to establish CGTxchange, a jointly owned entity that will serve as a clearinghouse and marketplace for deprioritized CGTs.

7 Jan 2026

Physical activity shows comparable benefits to therapy for treating depression

Exercise may reduce symptoms of depression to a similar extent as psychological therapy, according to an updated Cochrane review. When compared with antidepressant medication, exercise also showed a similar effect, but the evidence was of low certainty.

7 Jan 2026

Injectable nanomaterial reduces secondary brain injury after ischemic stroke

When a person suffers a stroke, physicians must restore blood flow to the brain as quickly as possible to save their life.

7 Jan 2026

Brazilian study shows liquid biopsies can expedite lung cancer care

In Brazil, the early detection of genetic alterations in lung cancer through liquid biopsies could be a valuable tool for expediting diagnoses and guiding patient treatment.

7 Jan 2026

Gene therapy breakthrough could provide hope for millions living with chronic pain

A preclinical study uncovered a new gene therapy that targets pain centers in the brain while eliminating the risk of addiction from narcotics treatments, a breakthrough which could provide hope for the more than 50 million Americans living with chronic pain.

7 Jan 2026

Breakthrough treatment for advanced prostate cancer could eliminate severe side effects

Researchers at Case Western Reserve University have developed a treatment for advanced prostate cancer that could eliminate a side effect so debilitating that patients often refuse the life-saving therapy.

7 Jan 2026

Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is among the most aggressive types of breast cancer, lacking estrogen, progesterone, and HER2 receptors and thus relying primarily on cytotoxic chemotherapy.

7 Jan 2026

Homeless shelters for seniors pop up, catering to older adults’ medical needs

Just outside Salt Lake City sits an old, two-story, brick hotel. It's been given new life as a homeless shelter for seniors. The Medically Vulnerable People shelter — or MVP shelter, as it's known — is for people 62 and older or for younger adults with chronic health issues.

7 Jan 2026

Low-dose megestrol strengthens hormone therapy in ER-positive breast cancer

Low-dose megestrol enhances hormone therapy for ER-positive breast cancer, reducing tumor proliferation and improving treatment adherence in the PIONEER trial.

7 Jan 2026

Parkinson’s disease may stem from iron starvation rather than iron overload

This perspective argues that Parkinson’s disease may involve functional iron deficiency, where bioavailable iron is limited despite normal or elevated total iron in the brain. The authors propose that iron sequestration, not iron toxicity alone, may impair dopamine synthesis and neuronal survival.

6 Jan 2026

Enveda’s third asset to the clinic with US FDA IND clearance: What it means for Inflammatory Bowel Disease

Enveda, a multi-asset clinical-stage biotech company pioneering the discovery and development of a new generation of small-molecule drugs derived from life’s chemistry, has announced that the US Food and Drug Administration (FDA) has cleared the Company’s Investigational New Drug (IND) application for ENV-6946.

From Hanson Wade Group - 4th Precision Medicine in Inflammatory Bowel Disease Summit 6 Jan 2026

A single immune protein may help explain why kidney and heart disease often develop together

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are strongly associated with kidney, cardiovascular, and metabolic disease risk. It highlights suPAR as a stable biomarker of innate immune activation with potential pathogenic roles, while underscoring major gaps in assay standardization and therapeutic validation.

6 Jan 2026

New database targets hidden causes of chronic urinary tract infections in children

A new database targeting chronic urinary tract infections (UTIs) – a long-overlooked condition that may begin in childhood – is set to help researchers uncover why millions of women and girls worldwide suffer from infections that defy treatment and stump microbiologists.

6 Jan 2026

New breakthrough could modernize treatment for glioblastoma

Researchers at the UNC School of Medicine and the UNC Eshelman School of Pharmacy have made a breakthrough that could modernize treatment for glioblastoma, a fast-growing and deadly form of brain cancer.

6 Jan 2026

ASTRO rebrands research foundation to accelerate innovation in radiation oncology

The American Society for Radiation Oncology (ASTRO) announced today that it rebranded its research foundation, formerly the Radiation Oncology Institute (ROI), as Speed of Light – The ASTRO Foundation, marking a new chapter in ASTRO's commitment to advancing research and improving patient care in radiation oncology.

6 Jan 2026

Chronic back pain linked to future sleep problems in older men

About half of older men suffer from sleep problems, back pain or both, according to Soomi Lee, associate professor of human development and family studies at Penn State.

6 Jan 2026

UH pharmacology professor wins $900,000 grant to develop a dual-function nanodrug for cancer

Accelerating advancements in cancer prevention and cures, Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, has received a $900,000 grant from the Cancer Prevention and Research Institute of Texas to develop stronger and more targeted anti-tumor therapy for pancreatic and lung cancer.

6 Jan 2026

Therapy News and Research

New partnership launches marketplace to revive deprioritized cell and gene therapies

Physical activity shows comparable benefits to therapy for treating depression

Injectable nanomaterial reduces secondary brain injury after ischemic stroke

Brazilian study shows liquid biopsies can expedite lung cancer care

Gene therapy breakthrough could provide hope for millions living with chronic pain

Breakthrough treatment for advanced prostate cancer could eliminate severe side effects

Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer

Homeless shelters for seniors pop up, catering to older adults’ medical needs

Low-dose megestrol strengthens hormone therapy in ER-positive breast cancer

Parkinson’s disease may stem from iron starvation rather than iron overload

Enveda’s third asset to the clinic with US FDA IND clearance: What it means for Inflammatory Bowel Disease

A single immune protein may help explain why kidney and heart disease often develop together

New database targets hidden causes of chronic urinary tract infections in children

New breakthrough could modernize treatment for glioblastoma

ASTRO rebrands research foundation to accelerate innovation in radiation oncology

Chronic back pain linked to future sleep problems in older men

UH pharmacology professor wins $900,000 grant to develop a dual-function nanodrug for cancer

TAAR1 mutation impairs brain signaling in schizophrenia

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Research points to major healthcare access challenges faced by young adults with IBD

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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