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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Waxman Foundation honors molecular biologist Alan Ashworth with the David T. Workman Memorial Award

Molecular biologist Alan Ashworth, Ph.D., FRS, the director of the Breakthrough Breast Cancer Research Centre at the Institute of Cancer Research in London will receive the David T. Workman Memorial Award on May 17. The two-year grant of $50,000 from the Samuel Waxman Cancer Research Foundation will support Dr. Ashworth's work with PARP inhibitors in BRCA-mutated cancers.

23 Apr 2010

TUM scientists collaborate with Fujitsu Laboratories of Japan to commercialize biosensor chip

In the battle against cancer and other diseases, precise analysis of specific proteins can point the way toward targeted treatments. Scientists at theTechnische Universitaet Muenchen, together with Fujitsu Laboratories of Japan, have developed a novel biosensor chip that not only recognizes proteins that are characteristic for specific diseases, but also can show if these proteins are changed through the influence of disease or drugs.

23 Apr 2010

Genetic tests that may replace biopsies

Genetic tests conducted on blood samples may replace the current biopsies when it comes to checking if immune systems are rejecting new organs of heart transplant patients. The test would be far less invasive and uncomfortable as compared to the biopsies, not to mention more affordable.

23 Apr 2010

Vical presents Phase 2 trial results of TransVax CMV vaccine at World Vaccine Congress

Vical Incorporated announced today that the company's TransVax cytomegalovirus vaccine elicited sustained increases in both cellular and antibody immune responses compared with placebo through the final 12-month follow-up in an ongoing Phase 2 trial in hematopoietic cell transplant recipients.

22 Apr 2010

Removable methyl groups on specific genes of autistic individuals that led to gene silencing identified

A new study by researchers at The George Washington University School of Medicine and Health Sciences' Department of Biochemistry and Molecular Biology raises hope that autism may be more easily diagnosed and that its effects may be more reversible than previously thought.

22 Apr 2010

Autonomy, Kainos release Evolve Electronic Document Management solution

Autonomy Corporation plc, a global leader in infrastructure software for the enterprise, and Kainos, a leading IT consulting company, today announced the launch of Evolve™, a next-generation Electronic Document Management solution which enables instant and secure access to patient medical records through Autonomy's unique Meaning Based Computing solutions. The new system is already being trail blazed by Ipswich Hospital NHS Trust and is the successful outcome of months of collaboration between Kainos and Autonomy.

22 Apr 2010

Research findings may help personalize use of statins, scientists say

Researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center have discovered why statins -- popular drugs that lower cholesterol and appear to protect against colorectal cancer development -- work for some people, but not for all.

22 Apr 2010

PharmaMar presents new trials with Yondelis, Zalypsis and Irvalec anti-tumor drugs at 101st AACR meeting

PharmaMar, a biopharmaceutical company owned by Grupo Zeltia (ZEL.MC), presented six new trials with marine-based anti-tumor drugs Yondelis(R), Zalypsis(R) and Irvalec(R) at the American Association for Cancer Research's (AACR) 101st Annual Meeting, held in Washington, D.C. from April 17-21.

22 Apr 2010

Study links mutations in RAD51C gene to breast and ovarian cancer

The discovery 15 years ago that the genes BRCA1 and BRCA2 confer high risks for breast and ovarian cancer was a breakthrough for cancer prediction and therapy, especially for familial cases. Now the research group of Prof. Alfons Meindl (Klinikum rechts der Isar of the Technische Universitaet Muenchen), in collaboration with other groups from Germany, the U.K., and the U.S., can identify another gene that increases susceptibility to breast and ovarian cancer.

22 Apr 2010

People with vitiligo may have less risk of developing malignant melanoma: Research

People with the skin pigmentation disorder vitiligo may have less risk of developing life-threatening malignant melanoma, according to new research. The study also further confirms the suspicion that vitiligo is an autoimmune disease, which occur when the body's immune system reacts against its own tissues or organs.

22 Apr 2010

Researchers detect link between alcohol consumption, cancer and aging

Researchers have detected a link between alcohol consumption, cancer and aging that starts at the cellular level with telomere shortening.

21 Apr 2010

ZIOP Chief Medical Officer receives grant to develop novel treatment for pediatric sarcoma

The Kristen Ann Carr Fund has awarded a grant to Jonathan Lewis, MD, PhD, Chief Executive Officer and Chief Medical Officer of ZIOPHARM Oncology, Inc., which will fund translational work at the Memorial Sloan-Kettering Cancer Center and the Albert Einstein College of Medicine in New York City, for the development of a novel treatment for pediatric sarcoma.

21 Apr 2010

NCGR deploys Isilon scale-out NAS to power genome sequencing research services

Isilon Systems today announced that the National Center for Genome Resources has deployed Isilon scale-out NAS to power its full range of next-generation genome sequencing research services. By combining Isilon's X-Series, Backup Accelerator and CommVault's Simpana backup software, NCGR has unified eight Illumina Genome Analyzers onto a highly reliable, central storage resource, accelerating time-to-results and ensuring its research information is secure and accessible 24x7x365.

21 Apr 2010

Inovio Biomedical wins Vaccine Industry Excellence Award in “Best Early Stage Biotech” category

Inovio Biomedical Corporation, a leader in DNA vaccine design, development and delivery, announced today that the company was awarded a Vaccine Industry Excellence Award in the category of "Best Early Stage Biotech" by a panel of judges composed of a broad selection of biotech industry stakeholders. The award was presented at the World Vaccine Congress being held April 19 - 22, 2010, in Washington, D.C.

21 Apr 2010

New method to analyze molecular activity of cancer drugs for solid tumors using skin biopsies

A research team today reported clinical results of a new method for analyzing the molecular activity of cancer drugs for solid tumors using skin biopsies. The approach, enabled by Cambridge Research & Instrumentation, Inc.'s imaging and analysis systems, was presented in a poster session at the American Association of Cancer Research's Annual Meeting in Washington D.C.

21 Apr 2010

Positive preclinical pharmacokinetic data for XMT-1001 presented at AACR 2010

Mersana Therapeutics, a platform-based cancer therapeutics company, announced today positive preclinical pharmacokinetic data for its lead development candidate, XMT-1001, which is currently in a Phase 1 clinical trial in patients with advanced solid tumors. The results were presented in a poster session at the AACR 101st Annual Meeting 2010 in Washington, DC, held April 17-21, 2010.

21 Apr 2010

Initial results of gallium-containing compound to treat serious infection presented at AACR 2010

Genta Incorporated today announced the presentation of initial results from the first human use of a gallium-containing compound to treat serious infection. In a patient with cystic fibrosis and a highly resistant lung infection, who has been treated over a 2-year period, high concentrations of gallium were achieved in sputum.

21 Apr 2010

MMRC Multiple Myeloma Genomics Initiative presented at AACR 2010

An analysis of 38 myeloma tumor genomes surveyed through extensive next-generation sequencing by the Broad Institute has revealed intriguing recurrent mutations that point to important cellular pathways which contribute to multiple myeloma. These data were revealed during an oral presentation entitled "First Impressions of the Multiple Myeloma Genome" by Todd R. Golub, MD, Director of the Cancer Program at the Eli and Edythe L. Broad Institute.

21 Apr 2010

New research shows mercury levels are higher in some tuna species

New research showing that that mercury levels are higher in some species of tuna could help consumers minimize their consumption of the silvery metal in their sushi and provide a powerful new tool for regulatory organizations.

21 Apr 2010

UK scientists find new drug for women with inherited form of ovarian cancer

A team of UK scientists, part-funded by Cancer Research UK, have found that a new type of drug could help women with an inherited form of ovarian cancer.

21 Apr 2010

DNA News and Research

Further Reading

Waxman Foundation honors molecular biologist Alan Ashworth with the David T. Workman Memorial Award

TUM scientists collaborate with Fujitsu Laboratories of Japan to commercialize biosensor chip

Genetic tests that may replace biopsies

Vical presents Phase 2 trial results of TransVax CMV vaccine at World Vaccine Congress

Removable methyl groups on specific genes of autistic individuals that led to gene silencing identified

Autonomy, Kainos release Evolve Electronic Document Management solution

Research findings may help personalize use of statins, scientists say

PharmaMar presents new trials with Yondelis, Zalypsis and Irvalec anti-tumor drugs at 101st AACR meeting

Study links mutations in RAD51C gene to breast and ovarian cancer

People with vitiligo may have less risk of developing malignant melanoma: Research

Researchers detect link between alcohol consumption, cancer and aging

ZIOP Chief Medical Officer receives grant to develop novel treatment for pediatric sarcoma

NCGR deploys Isilon scale-out NAS to power genome sequencing research services

Inovio Biomedical wins Vaccine Industry Excellence Award in “Best Early Stage Biotech” category

New method to analyze molecular activity of cancer drugs for solid tumors using skin biopsies

Positive preclinical pharmacokinetic data for XMT-1001 presented at AACR 2010

Initial results of gallium-containing compound to treat serious infection presented at AACR 2010

MMRC Multiple Myeloma Genomics Initiative presented at AACR 2010

New research shows mercury levels are higher in some tuna species

UK scientists find new drug for women with inherited form of ovarian cancer

Understanding the DNA Damage Response in Innate Immunity eBook

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