Antibiotic Resistance News and Research

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New rifamycin drugs fight antibiotic-resistant lung infections more effectively

Researchers have developed next-generation rifamycin analogs that effectively kill both replicating and nonreplicating Mycobacterium abscessus while minimizing drug-drug interactions. Lead candidates UMN-120 and UMN-121 showed superior efficacy to current treatments in mouse models and retained potency against M. tuberculosis.

5 May 2025

Rising antibiotic resistance threatens UTI treatment in Malawi

A growing resistance to antibiotics is complicating the treatment of urinary tract infections (UTIs) in Malawi, with new research revealing that nearly half of women presenting with symptoms at a major referral hospital had infections resistant to multiple drugs.

3 May 2025

Mathematical models point to broader antibiotic use as a tool against cholera

Cholera kills thousands of people and infects hundreds of thousands every year-and cases have spiked in recent years, leaving governments with an urgent need to find the best ways to control outbreaks.

29 Apr 2025

Research offers new hope in the fight against antibiotic-resistant bacteria

Antibiotic resistance is a serious threat to public health. When antibiotics don't work, we risk not being able to treat many types of infections and people who would previously have been cured, can die.

23 Apr 2025

New approach to treating chronic pain without opioids

Chronic pain, a common and debilitating condition, often leads practitioners to prescribe opioids in escalating doses.

22 Apr 2025

Fecal microbiota transplantation emerges as a promising approach to H. pylori eradication

FMT is a novel therapeutic approach that involves transferring microbiota from a healthy donor to a patient's gastrointestinal tract.

10 Apr 2025

Unexpected function of gene network in gut microbes revealed

Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers from the Institute of Science and Technology Austria (ISTA) show this is an auxiliary function.

8 Apr 2025

AI model enhances detection of antibiotic resistance in deadly bacteria

Drug-resistant infections - especially from deadly bacteria like tuberculosis and staph - are a growing global health crisis.

7 Apr 2025

New guidelines aim to improve diagnosis and treatment of mycoplasma pneumoniae in children

The Chinese Medical Association has released new guidelines for diagnosing and treating Mycoplasma pneumoniae in children.

7 Apr 2025

New insights into bacterial defense mechanisms could help combat antibiotic resistance

Antibiotic resistance is a global health challenge that could overtake cancer mortality within a few decades.

4 Apr 2025

European study reveals stabilization patterns in antibiotic resistance

Antibiotic resistance tends to stabilize over time, according to a study published April 3, 2025 in the open-access journal PLOS Pathogens by Sonja Lehtinen from the University of Lausanne, Switzerland, and colleagues.

4 Apr 2025

Study: Jumbo phages utilize EPI vesicles to evade bacterial immune response

In a growing global trend, bacteria have evolved new ways to maneuver around medical treatments for a variety of infections. The rising antibiotic resistance crisis poses a significant public health threat in hospitals and other settings, with infections resulting in millions of deaths in recent years.

4 Apr 2025

New bacterial evolutionary map could lead to precision treatments for infections

The first-of-its-kind in-depth bacterial evolutionary map could pave the way for the development of precision treatments for certain antibiotic-resistant infections, such as urinary tract infections.

3 Apr 2025

New drug strategy targets Staphylococcus aureus toxin to treat pneumonia

Pneumonia caused by the bacterium Staphylococcus aureus is one of the most dangerous infections that can occur in hospital.

2 Apr 2025

New class of antibiotic selectively targets gonorrhea bacterium

Researchers from the universities in Konstanz and Vienna discover a new class of antibiotic that selectively targets Neisseria gonorrhoeae, the bacterium that causes gonorrhea.

2 Apr 2025

AI predicts bacterial resistance to antibiotics with high accuracy

An AI model trained on large amounts of genetic data can predict whether bacteria will become antibiotic-resistant.

2 Apr 2025

New antibiotic-resistant superbug discovered in Malaysian hospital

A virulent strain of antibiotic-resistant 'superbug' that causes severe disease has been found circulating in a Malaysian hospital - posing significant challenges to global public health, a new study reveals.

1 Apr 2025

New peptide antibiotic stops bacteria by binding where no drug has before

Researchers discovered lariocidin, a lasso peptide antibiotic that kills multidrug-resistant bacteria by binding a novel ribosomal site.

27 Mar 2025

Breakthrough discovery could lead to new class of antibiotics

The last time a new class of antibiotics reached the market was nearly three decades ago - but that could soon change, thanks to a discovery by researchers at McMaster University.

26 Mar 2025

Study finds a promising alternative strategy for combating H. pylori infections

This study is reported by Lizeng Gao's group from the Institute of Biophysics, Chinese Academy of Sciences, Beijing. The growing issue of antibiotic resistance necessitates alternative treatments for the highly prevalent Helicobacter pylori infection.

22 Mar 2025