Antidepressant News and Research

RSS

Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Stanford study identifies six depression biotypes for personalized treatment

In the not-too-distant future, a screening assessment for depression could include a quick brain scan to identify the best treatment.

17 Jun 2024

Approximately 1 in 6 patients experience antidepressant withdrawal symptoms, systematic review finds

Researchers performed a meta-analysis to determine the prevalence of antidepressant discontinuation symptoms.

13 Jun 2024

Study links antidepressant use and epigenetic aging to higher mortality risk in postmenopausal women

The impact of depressive symptoms, use of antidepressants, and epigenetic age acceleration (EAA) on mortality in postmenopausal individuals.

13 Jun 2024

Heavy cannabis use increases the risk of cardiovascular disease for women, study finds

Whether cannabis use is linked to mortality.

11 Jun 2024

Exploring the biology behind maternal mental health disorders

Pregnancy and new motherhood transform a woman's body as well as her life. While this is often a joyous time, it can sometime lead to mental health disorders, most often anxiety and depression.

6 Jun 2024

Common drugs linked to reduced risk of bleeding stroke from brain aneurysm

A new study suggests that people who take a few common drugs may have a decreased risk of having a bleeding stroke due to a ruptured brain aneurysm.

5 Jun 2024

Study examines prescribing patterns of tricyclic antidepressants for treatment of diabetic peripheral neuropathy

Many adults with diabetes and the associated complication of peripheral neuropathy, which can be painful as well as harmful, are often prescribed drugs at doses and for durations that could impose an increased risk of cognitive impairment.

30 May 2024

New AI tool analyzes medical history to match patients with best antidepressant

Researchers in George Mason University's College of Public Health have leveraged the power of artificial intelligence (AI) analytical models to match a patient's medical history to the most effective antidepressant, allowing patients to find symptom relief sooner.

30 May 2024

Psychoactive drugs are having a moment. The FDA will soon weigh in.

Lori Tipton is among the growing number of people who say that MDMA, also known as ecstasy, saved their lives.

29 May 2024

Running therapy matches antidepressants for mental health, surpasses for physical benefits

Researchers found that while both antidepressants and group running therapy effectively improved mental health in patients with anxiety and depression, running therapy had significantly better outcomes for physical health indicators.

26 May 2024

Study offers new insights into how ketamine works

A World Health Organization Essential Medicine, ketamine is widely used at varying doses for sedation, pain control, general anesthesia and as a therapy for treatment-resistant depression.

21 May 2024

Innovative 'mini-brains' could revolutionize Alzheimer's diagnosis and treatment

Using an innovative new method, a University of Saskatchewan (USask) researcher is building tiny pseudo-organs from stem cells to help diagnose and treat Alzheimer's.

14 May 2024

Novel head-mounted device shows promise in alleviating depression symptoms

A head-mounted device that generates an ultra-low frequency ultralow magnetic field has been found to improve the symptoms of four male patients diagnosed with major depressive disorder.

8 May 2024

Efficient intranasal delivery of agomelatine via micellar encapsulation

Announcing a new publication for Acta Materia Medica journal. Agomelatine (AGO) is an antidepressant with limited clinical application due to its low bioavailability caused by poor water solubility, severe hepatic degradation, and poor intracerebral distribution.

6 May 2024

Psilocybin found to be more effective than controls for treating depression symptoms

Psilocybin - the active ingredient in "magic" mushrooms - is a more effective treatment for symptoms of depression than controls, providing further support for its potential as an antidepressant, suggests a study published by The BMJ today.

1 May 2024

Early life stress may underlie a pathophysiological exacerbation of postpartum depression

In a new study, a Johns Hopkins Medicine-led research team reports that social stress during adolescence in female mice later results in prolonged elevation of the hormone cortisol after they give birth.

16 Apr 2024

Ketamine's rapid impact on depression linked to immune system pathways

Study reveals ketamine's potent anti-inflammatory effects on neurological disorders, showing promise for treating major depressive disorder through modulation of neuroimmune pathways.

15 Apr 2024

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Low-dose esketamine administered post-labor significantly reduced depressive symptoms in women with prenatal depression within 42 days, despite an increase in short-lived neuropsychiatric side effects.

14 Apr 2024

Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems - prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, prolonged use also can create an extreme sensitivity to pain, called hyperalgesia.

9 Apr 2024

Depression impacts survival rates and quality of life for women with breast cancer

A new study presented at the European Psychiatric Association Congress 2024 sheds light on the significant impact of depression on the survival rates and quality of life for women diagnosed with breast cancer.

8 Apr 2024