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Zebrafish can play a decisive role in clinical interpretation of spinal muscular atrophy

The tiny zebrafish is helping researchers rapidly determine whether a newborn's genetic mutation is likely to cause spinal muscular atrophy (SMA), one of the leading causes of infant mortality worldwide.

28 Jan 2026

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not.

27 Jan 2026

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, particularly in regions with high hepatitis B virus prevalence.

24 Jan 2026

New chip-based test could revolutionize blood transfusions

A new, fast and easy test could revolutionize blood transfusions-giving blood centers and hospitals a reliable way to monitor the quality of red blood cells after they sit for weeks in storage.

21 Jan 2026

Sino Biological's launch of SwiftFluo® TR-FRET Kits pioneers a new era in high- throughput kinase inhibitor screening

Sino Biological, Inc. is proud to announce the launch of its innovative SwiftFluo TR-FRET Kinase Assay Kits, a ready-to-use, high-performance solution designed to accelerate kinase activity detection and high-throughput kinase inhibitor screening.

From Sino Biological Inc. 21 Jan 2026

COVID-19 severity is linked to changes in mitochondrial DNA methylation

This study examined mitochondrial and nuclear-encoded mitochondrial DNA methylation in Indian patients with severe COVID-19 and found region-specific differential methylation linked to disease severity. Pathway analyses and protein assays implicated disrupted mitochondrial metabolism and dynamics, suggesting a role for mitochondrial epigenetic regulation in COVID-19 pathophysiology.

20 Jan 2026

Blood lipid–hormone ratios predict future asthma attacks years in advance

This study shows that specific ratios of circulating sphingolipids to steroids can predict the risk of future asthma exacerbations over five years with high discriminatory performance. By integrating metabolomics with longitudinal medical records, the research highlights lipid–hormone pathway imbalance as a key driver of asthma instability.

20 Jan 2026

The challenge of tracking asymptomatic Mpox

The mpox virus appears to be circulating silently in parts of Nigeria, in many cases without the symptoms typically associated with the disease, according to new research led by scientists from the University of Cambridge and partners in Nigeria. The findings may have implications for controlling the spread of the disease.

20 Jan 2026

Accelerating kinase drug discovery with validated kinase activity assay kits

The development of new therapeutics targeting protein kinases is crucial in the fight against diseases like cancer.

From Eurofins Discovery 20 Jan 2026

Genomic screening uncovers hidden cancer and heart disease risk in young adults

A nationwide Australian pilot screened more than 10,000 adults aged 18–40 years for high-risk genetic variants linked to hereditary cancer and familial hypercholesterolaemia, identifying clinically actionable findings in about 2% of participants.

19 Jan 2026

Novel method predicts asthma exacerbations with high degree of accuracy

Researchers at Mass General Brigham and Karolinska Institutet have identified a new method to predict asthma exacerbations with a high degree of accuracy. The study is published in Nature Communications.

19 Jan 2026

Global Alzheimer’s Platform Foundation announces strategic collaboration and partnership with Spear Bio for the transformative Bio-Hermes-002 study

The Global Alzheimer’s Platform Foundation® (GAP) is pleased to welcome Spear Bio, a biotechnology company pioneering wash-free ultrasensitive immunoassay technology, to the Bio-Hermes-002 study.

From Spear Bio 18 Jan 2026

Single-cell technique maps pre-malignant gene mutations in solid tissues

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the New York Genome Center.

16 Jan 2026

Formulatrix® and Spear Bio advance automated ultrasensitive protein detection through ongoing partnership

Formulatrix, a leader in laboratory automation solutions, and Spear Bio, an innovator in ultrasensitive protein biomarker detection, today announced their ongoing partnership to automate and optimize the SPEAR UltraDetect™ assay platform using the F.A.S.T.™ (Flow Axial Seal Tip) Liquid Handler.

From Spear Bio 15 Jan 2026

New test could improve future diagnosis and monitoring of IBD

A test that rapidly detects signs of inflammatory bowel disease (IBD) in stool samples could improve future diagnosis and monitoring of the condition, a study suggests.

13 Jan 2026

Targeting IDO1 for cancer: Novel degraders show promise in preclinical studies

Cancer cells employ a variety of strategies to evade the immune system, and modern immunotherapies aim precisely at these escape mechanisms.

9 Jan 2026

TAAR1 mutation impairs brain signaling in schizophrenia

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence a brain receptor that pharmaceutical companies are racing to target with new drugs.

6 Jan 2026

Understanding sevoflurane-induced neurogenesis inhibition and cognitive dysfunction in children

Every year, millions of infants and children undergo surgery under general anesthesia in the world. Sevoflurane is a commonly used pediatric anesthetic. Its exposure during brain development has been shown to inhibit neurogenesis and cause cognitive dysfunction in animal models.

5 Jan 2026

Jumping genes reshape cancer genomes through 3D chromatin interactions

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

5 Jan 2026

COVID-19 immunity stays specific and barely boosts protection against common cold coronaviruses

This study shows that SARS-CoV-2 infection and vaccination generate strong, highly specific spike-binding immune responses with only modest effects on immunity to endemic common cold coronaviruses. Pre-existing coronavirus immunity patterns remain largely intact, indicating that SARS-CoV-2 has integrated into the human viral landscape without broadly reshaping cross-reactive protection.

5 Jan 2026

Assay News and Research

Zebrafish can play a decisive role in clinical interpretation of spinal muscular atrophy

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

New chip-based test could revolutionize blood transfusions

Sino Biological's launch of SwiftFluo® TR-FRET Kits pioneers a new era in high- throughput kinase inhibitor screening

COVID-19 severity is linked to changes in mitochondrial DNA methylation

Blood lipid–hormone ratios predict future asthma attacks years in advance

The challenge of tracking asymptomatic Mpox

Accelerating kinase drug discovery with validated kinase activity assay kits

Genomic screening uncovers hidden cancer and heart disease risk in young adults

Novel method predicts asthma exacerbations with high degree of accuracy

Global Alzheimer’s Platform Foundation announces strategic collaboration and partnership with Spear Bio for the transformative Bio-Hermes-002 study

Single-cell technique maps pre-malignant gene mutations in solid tissues

Formulatrix® and Spear Bio advance automated ultrasensitive protein detection through ongoing partnership

New test could improve future diagnosis and monitoring of IBD

Targeting IDO1 for cancer: Novel degraders show promise in preclinical studies

TAAR1 mutation impairs brain signaling in schizophrenia

Understanding sevoflurane-induced neurogenesis inhibition and cognitive dysfunction in children

Jumping genes reshape cancer genomes through 3D chromatin interactions

COVID-19 immunity stays specific and barely boosts protection against common cold coronaviruses

Measuring Drug-Target Residence Times with Biochemical Assays eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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