Geriatrics News and Research

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Elevated PGE2 levels drive age-related skin changes and cancer risk

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 21 on November 18, 2024, entitled, "Prostaglandin E2 regulates senescence and post-senescence neoplastic escape in primary human keratinocytes."

11 Dec 2024

Understanding the role of sleep in dementia and associated illnesses

A new review was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 21, titled, "Sleep deprivation in dementia comorbidities: focus on cardiovascular disease, diabetes, anxiety/depression and thyroid disorders."

2 Dec 2024

Telemedicine and peer support show promise in treating hepatitis C in rural areas

New research reveals a dramatic improvement in diagnosing and curing people living with hepatitis C in rural communities using both telemedicine and support from peers with lived experience in drug use.

27 Nov 2024

Addressing the challenges of cognitive impairment detection in primary care

Early detection of cognitive impairment is essential for improving patient outcomes, but primary care settings face significant challenges in screening. This special report summarizes key points and gaps in knowledge about methods for detecting cognitive impairment in primary care clinics.

25 Nov 2024

Hamilton and Amabel James Center for AI and Human Health launches at Mount Sinai

Today, the Mount Sinai Health System, one of New York City's largest academic medical systems, announced the opening of the Hamilton and Amabel James Center for Artificial Intelligence and Human Health, which is dedicated to enhancing health care delivery through the research, development, and application of innovative artificial intelligence (AI) tools and technologies.

25 Nov 2024

Researchers develop new approach to effectively deliver therapeutics into the brain

Researchers at the Icahn School of Medicine at Mount Sinai have developed an innovative approach - demonstrated in mouse models and isolated human brain tissue - to safely and effectively deliver therapeutics into the brain, providing new possibilities for treating a wide range of neurological and psychiatric diseases.

25 Nov 2024

Exploring how biological clocks measure aging and predict mortality

This review was published by Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), in Volume 16, Issue 17, titled, "A systematic review of phenotypic and epigenetic clocks used for aging and mortality quantification in humans."

21 Nov 2024

New insights into brain aging and Alzheimer's from non-human primates

A new review was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), on October 29, 2024, Volume 16, Issue 20, titled, "Brain aging and Alzheimer's disease, a perspective from non-human primates."

20 Nov 2024

Study identifies cost-effective strategies for using AI in health systems

A study by researchers at the Icahn School of Medicine at Mount Sinai has identified strategies for using large language models (LLMs), a type of artificial intelligence (AI), in health systems while maintaining cost efficiency and performance.

18 Nov 2024

Unclear responsibilities hinder oral health care in nursing homes

Healthcare workers at nursing homes face a major challenge when helping older adults to maintain their oral hygiene.

15 Nov 2024

Electronic frailty index validated for predicting health complications in seniors

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), on October 24, 2024, Volume 16, Issue 20, titled, "Development and validation of an electronic frailty index in a national health maintenance organization."

12 Nov 2024

AI tool tracks infant movement to predict neurologic changes in NICU

A team of clinicians, scientists, and engineers at Mount Sinai trained a deep learning pose-recognition algorithm on video feeds of infants in the neonatal intensive care unit (NICU) to accurately track their movements and identify key neurologic metrics.

11 Nov 2024

Mount Sinai researchers uncover key process in memory integration

Mount Sinai researchers have discovered for the first time a neural mechanism for memory integration that stretches across both time and personal experience.

6 Nov 2024

Werner syndrome gene plays key role in maintaining cellular organization and DNA stability

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 20 on October 17, 2024, entitled, "Werner syndrome RECQ helicase participates in and directs maintenance of the protein complexes of constitutive heterochromatin in proliferating human cells."

5 Nov 2024

Revised diagnostic criteria seek to avoid over-diagnosis of Alzheimer’s disease

Diagnosis of Alzheimer's Disease (AD) is currently largely based on the presence of biomarkers. This may lead to a problematic over-diagnosis if this is incorrectly interpreted.

5 Nov 2024

Enhanced screening protocols for Candida auris improve hospital infection control

Mount Sinai researchers have enhanced hospital screening protocols for Candida auris, an often-drug-resistant fungal pathogen the Centers for Disease Control and Prevention considers an urgent global health threat.

1 Nov 2024

New therapeutic target overcomes ovarian cancer immunotherapy resistance

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way that ovarian cancer tumors manipulate their environment to resist immunotherapy and identified a drug target that could overcome that resistance.

1 Nov 2024

New antibody platform targets evolving viruses

Scientists at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues in the field, have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.

23 Oct 2024

Senolytic agents show promise in mouse model of pelvic organ prolapse

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 19 on September 26, 2024, entitled, "Use of the senolytics dasatinib and quercetin for prevention of pelvic organ prolapse in a mouse animal model."

22 Oct 2024

Major study links loneliness to increased risk of dementia

New research led by Florida State University College of Medicine faculty quantified the association between loneliness and dementia by analyzing data from more than 600,000 people around the world - the largest study of its kind.

21 Oct 2024