Lipids News and Research

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Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.

Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries

Wiley expands its spectral database with over 9.5 million high-quality spectra, enhancing compound identification for researchers in various scientific fields.

From John Wiley and Sons - Scientific Publishers 24 Nov 2025

CAR T cell therapy could be a highly effective tool against atherosclerosis

A pioneering preclinical study has shown that CAR T cell therapy-a personalized form of immunotherapy used in cancer treatment-could be a highly effective tool against atherosclerosis, the condition where a build-up of plaque in the arteries reduces blood flow, leading to heart attacks and strokes.

21 Nov 2025

Changes in brain fats play a key role in Alzheimer's development and progression

More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid-beta (amyloid) plaques and tau protein tangles.

20 Nov 2025

Coffee protects the brain, metabolism, and immunity at the molecular level

This review uncovers the molecular networks of coffee's compounds, showcasing their antioxidant and neuroprotective effects on immunity and metabolism.

19 Nov 2025

Oral semaglutide delivers real-world drops in blood sugar and weight in diabetes trial

Oral semaglutide delivered meaningful reductions in HbA1c and body weight among GLP-1RA-naïve adults with type 2 diabetes in a Dutch real-world cohort. Lipid levels and blood pressure showed only small changes, reflecting modest cardiometabolic effects outside glucose and weight control.

18 Nov 2025

Trial investigates how quickly human milk responds to common plant based meat swaps

Replacing beef with a plant based beef substitute for six days changed the fatty acid composition of human milk, increasing medium chain saturated fats and lowering key long chain polyunsaturated fats such as arachidonic acid. These biochemical shifts occurred without changes in maternal weight, appetite, glucose patterns or infant milk intake.

18 Nov 2025

Daily black cumin intake improves blood lipids and reduces obesity risk

Nigella sativa (black cumin), the spice that boosts the flavor of curries like korma and paneer also has another use: its seeds have long been used as a medicinal plant in traditional medicine for their antioxidant and anti-inflammatory effects.

18 Nov 2025

VR raises eye temperature and thickens protective tear layer

VR gaming impacts tear film dynamics, increasing lipid layer thickness and eye temperature, but fails to enhance tear stability or alleviate dry eye symptoms.

14 Nov 2025

Whole genome sequencing reveals how much human heritability we can finally explain

Whole genome sequencing in nearly 500,000 UK Biobank participants shows that observed rare and common variants now explain about 88% of family based heritability for many human traits. By partitioning heritability into rare versus common and coding versus non-coding components, the study narrows where missing heritability still hides and highlights traits that remain only partly understood.

13 Nov 2025

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Replacing APOE4 with APOE2 in adult mice rapidly reshapes brain lipids and gene expression, even after development is complete. This switch, especially when targeted to astrocytes, reduces amyloid burden, dampens gliosis, and improves associative memory despite E2-like peripheral lipid risks.

12 Nov 2025

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

Obstructive sleep apnea (OSA), a global public health issue marked by repeated upper airway collapse during sleep, is tied to diverse diseases-from cardiovascular conditions to cancer.

12 Nov 2025

New data supports earlier use of evolocumab in high-risk diabetes

Adding the PCSK9 inhibitor evolocumab to a high-intensity, cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with atherosclerotic cardiovascular disease (ASCVD) or diabetes , according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Novel triple receptor agonist shows potent efficacy in lowering high triglycerides

In a small, short duration trial (12 weeks), a new medication called DR10624 reduced triglyceride levels in most patients with severe hypertriglyceridemia by more than 60%, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Diabetes drugs semaglutide and tirzepatide show real-world heart benefits

In a large real-world analysis across three U.S. healthcare databases, semaglutide and tirzepatide showed cardiovascular benefits consistent with randomized trials. Semaglutide lowered heart attack and stroke risk versus sitagliptin, while tirzepatide performed comparably to dulaglutide and semaglutide over one year.

10 Nov 2025

Daily oral medication matches injectable therapies in reducing bad cholesterol

Among people with a previous heart attack or stroke, or who are at high risk for one, a daily oral medication may offer an effective alternative to injections of PCSK9 inhibitors to lower low-density lipoprotein (LDL or "bad" cholesterol), according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Regular orange juice consumption reprograms immune-cell gene activity linked to blood pressure, lipid metabolism, and inflammation in healthy adults. The molecular effects differ by body weight, suggesting BMI-tailored benefits from this everyday beverage.

9 Nov 2025

New delivery particle could make mRNA vaccines cheaper and more effective

A new delivery particle developed at MIT could make mRNA vaccines more effective and potentially lower the cost per vaccine dose.

7 Nov 2025

Study finds high intake of ultra-processed foods tied to reduced DNA methylation

Women who consumed more ultra-processed foods (UPFs) showed distinct DNA methylation patterns, mostly reduced across key gene regions. These exploratory findings suggest that high UPF intake may influence gene regulation through epigenetic mechanisms.

4 Nov 2025

Swapping meat for plant-based options cuts fat but lowers protein, study finds

Replacing meat with plant-based or mycoprotein alternatives in UK diets lowers saturated fat and boosts fiber but reduces protein intake, especially for teens and older adults. The overall saturated fat reduction is too small to meaningfully affect cholesterol levels, researchers report in npj Science of Food.

4 Nov 2025

Inconsistent labels and risky doses found in turmeric supplements worldwide

A global analysis of 125 turmeric supplements across five major markets revealed widespread inconsistencies in labeling, dosage, and regulatory compliance. Over a third lacked curcuminoid content disclosure, and nearly one-third exceeded safe intake levels, exposing consumers to unverified and potentially risky formulations.

3 Nov 2025

Lipids News and Research

Further Reading

Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries

CAR T cell therapy could be a highly effective tool against atherosclerosis

Changes in brain fats play a key role in Alzheimer's development and progression

Coffee protects the brain, metabolism, and immunity at the molecular level

Oral semaglutide delivers real-world drops in blood sugar and weight in diabetes trial

Trial investigates how quickly human milk responds to common plant based meat swaps

Daily black cumin intake improves blood lipids and reduces obesity risk

VR raises eye temperature and thickens protective tear layer

Whole genome sequencing reveals how much human heritability we can finally explain

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

New data supports earlier use of evolocumab in high-risk diabetes

Novel triple receptor agonist shows potent efficacy in lowering high triglycerides

Diabetes drugs semaglutide and tirzepatide show real-world heart benefits

Daily oral medication matches injectable therapies in reducing bad cholesterol

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

New delivery particle could make mRNA vaccines cheaper and more effective

Study finds high intake of ultra-processed foods tied to reduced DNA methylation

Swapping meat for plant-based options cuts fat but lowers protein, study finds

Inconsistent labels and risky doses found in turmeric supplements worldwide

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