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Experimental therapy eliminates pancreatic precancerous cells in mice study

A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors.

12 Mar 2026

Adding three simple amino acids boosts mRNA and CRISPR delivery

Lipid nanoparticles, or LNPs, best known as the delivery vehicle for the COVID-19 mRNA vaccines received by billions of people, are now at the center of a much larger medical revolution.

12 Mar 2026

Scientists map epigenetic changes across aging brain cells

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.

11 Mar 2026

Novel microneedle patch accelerates healing of chronic diabetic wounds using light

Researchers from Nanjing Drum Tower Hospital, Southeast University, and Wenzhou Medical University have developed a novel microneedle patch that combines MXene hydrogel with nitric oxide (NO) and hypoxia-inducible factor-1α (HIF-1α) plasmid for enhanced diabetic wound treatment.

10 Mar 2026

Med14 protein drives GLP-1 benefits in pancreatic beta cells

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve cardiovascular health.

6 Mar 2026

Ketone body can strengthen the fitness and antitumor activity of CAR T cells

A naturally occurring byproduct of liver metabolism–the ketone body, β-hydroxybutyrate (BHB)–can strengthen the fitness and antitumor activity of CAR T cells.

6 Mar 2026

Low-intensity preconditioning boosts neurological outcomes

The team led by Prof. Lin Zhu from Guangzhou Sport University have demonstrated that 4-week low-intensity treadmill exercise before the onset of an ischemic stroke can significantly reduce brain injury and improve neurological outcomes.

4 Mar 2026

Researchers identify TRIM13 protein as key driver of immune suppression in sepsis

Dendritic cells (DCs) are increasingly recognized as important contributors to sepsis-associated immune dysfunction.

4 Mar 2026

Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

Sepsis and severe pneumonia are frequently accompanied by disruption of the gut microbiota, leading to immune dysfunction and increased susceptibility to secondary infections.

4 Mar 2026

Targeted fluorescent probes for high-contrast cancer detection

Cancer is a universal issue that affects uncountably many people around the world. Many will turn to surgery in the hope that a surgeon will be able to completely remove a tumor, leaving healthy tissues unaffected. Various tools and techniques have been developed over the years to improve the way these surgeries are performed, and visual imaging methods such as glowing dyes have proven to be very useful.

2 Mar 2026

New pathway found connecting liver congestion to fibrosis and cancer

Researchers from The University of Osaka find that chronic liver congestion is linked to severe liver diseases through a specific signaling pathway in liver sinusoidal endothelial cells - key cells lining the liver's tiny blood vessels.

27 Feb 2026

Corneal nerve function declines with age in aniridia patients

Congenital aniridia is a rare disease caused, in most cases, by mutations in the PAX6 gene, which is essential for the development of ocular structures.

27 Feb 2026

New mouse model uncovers achondroplasia's cellular growth plate dysregulation

Achondroplasia, also known as short-limb dwarfism, is associated with neurological symptoms and complications due to narrowing of the skeletal structures surrounding the spinal cord.

26 Feb 2026

Vitamin B3 shows promise for treating rare genetic disorder

Scientists at Gladstone Institutes have flipped the traditional approach to finding potential treatments for deadly diseases.

25 Feb 2026

Lingering brain inflammation found after mild COVID infection

Even a mild case of COVID-19 or the flu can impact the body long after the fever and cough fade, according to new Tulane University research that may help explain why some people struggle to feel fully recovered weeks or months later.

25 Feb 2026

Tirzepatide activates brown fat, boosting metabolism beyond appetite control

Tirzepatide is one of the drugs that has revolutionized the treatment of obesity and other conditions such as diabetes in recent years.

24 Feb 2026

Early exposure to unhealthy foods leaves lasting brain and feeding changes

Eating unhealthy foods early in life leave lasting brain and feeding changes but gut bacteria can help restore healthy eating, new University College Cork (UCC) research study finds today (Tuesday 24th February 10am)

24 Feb 2026

Throwing cancer-driving proteins in the cellular trash

When cancer-driving proteins resist various treatments, Northwestern University scientists have uncovered a new solution. Don't fight them - throw them in the cellular trash.

24 Feb 2026

Rytvela lowers inflammation and improves newborn survival in preclinical study

New research shows that Rytvela, an anti-inflammatory drug candidate, decreased premature birth and infant mortality when administered after the onset of preterm labor in a preclinical mouse model.

23 Feb 2026

Researchers show red blood cells drive better glucose tolerance at high altitude

Chronic hypoxia improves glucose tolerance in mice through insulin-independent mechanisms, with red blood cells acting as a major systemic glucose sink. Increased erythrocyte production and altered glycolytic flux help reduce circulating glucose while supporting oxygen delivery to tissues.

22 Feb 2026