Neural Stem Cells News and Research

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Promising approach to stem cell therapy for treating Parkinson's disease

A major factor underlying Parkinson's Disease pathology is the loss of dopamine neurons in the substantia nigra, and thus current therapies often aim to restore dopamine signaling. However, these treatments are not curative.

24 Jul 2018

Novel, stem cell-based model mimics mechanisms of Alzheimer's disease

Scientists in Dresden, Germany, have been successful in mimicking mechanisms of Alzheimer's disease in a novel, stem cell-based model system that reproduces features of human brain tissue.

3 Jul 2018

Discovery may be key to directly reprogram non-neuronal cells into neurons

It was already in 2012 that a team of scientists headed by Professor Benedikt Berninger first succeeded in reprogramming connective tissue cells present in the brain into neurons.

2 Jul 2018

City of Hope receives $3.7 million from CIRM to develop phase 1 glioblastoma trial

The California Institute for Regenerative Medicine board has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients that will genetically engineer their stem cells to better tolerate chemotherapy's side effects, allowing them to receive higher doses of the therapy.

30 Jun 2018

Study provides insight into development of autism in the human brain

In a study published in Stem Cell Reports, a McGill team of scientists led by Dr. Carl Ernst, researcher at the Douglas Hospital Research Centre, revealed a molecular mechanism that may play a role in the development of autism.

27 Jun 2018

Researchers invent medical device for proliferation, differentiation of neural stem cells

The research team of Hong Kong Baptist University invented a medical device with a specific nanotechnology layer for the proliferation and differentiation of neural stem cells in vitro.

20 Jun 2018

New research provides clues into development of mammalian cerebral cortex

The cerebral cortex - the brain's epicenter of high-level cognitive functions, such as memory formation, attention, thought, language and consciousness - has fascinated neuroscientists for centuries.

8 Jun 2018

Researchers reveal stimulatory effects of myelin on young neural cells

Recovery after severe spinal cord injury is notoriously fraught, with permanent paralysis often the result. In recent years, researchers have increasingly turned to stem cell-based therapies as a potential method for repairing and replacing damaged nerve cells.

24 May 2018

Flow of cerebrospinal fluid found to be key signal for neural stem cell renewal

Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory.

21 May 2018

Scientists successfully graft neural precursor cells into spinal cords of syngeneic pigs with no immunosuppression

A major hurdle to using neural stem cells derived from genetically different donors to replace damaged or destroyed tissues, such as in a spinal cord injury, has been the persistent rejection of the introduced material, necessitating the use of complex drugs and techniques to suppress the host's immune response.

10 May 2018

Researchers shed new light on identity of brain stem cells

The human nervous system is a complex structure that sends electrical signals from the brain to the rest of the body, enabling us to move and think. Unfortunately, when brain cells are damaged by trauma or disease they don't automatically regenerate. This can lead to permanent disability.

4 May 2018

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

A Brazilian study published April 26 in the journal Cancer Research shows for the first time in vivo that Zika virus can be used as a tool to treat aggressive human central nervous system (CNS) tumors.

27 Apr 2018

Viruses can exploit a suprising weakness of brain cells to spark hydrocephalus

Viruses may spark hydrocephalus by exploiting a suprising weakness of cells that circulate fluid in the brain, says a new study by Duke University scientists.

25 Apr 2018

Neurogenesis diminishes after childhood, finds study

In a recent study, scientists concluded that adult neurogenesis, which is seen in other species, does not occur in human beings.

8 Mar 2018

Scientists identify genes involved in age-related brain deterioration

A group of genes and genetic switches involved in age-related brain deterioration have been identified by scientists at the Babraham Institute, Cambridge and Sapienza University, Rome.

5 Mar 2018

New study provides better understanding of asymmetric cell division

Stem cells are the basic material from which mature, specialised cells such as muscle and blood cells are produced -- this process is known as differentiation.

28 Feb 2018

Researchers successfully graft human neural stem cells into monkeys with spinal cord injuries

Led by researchers at University of California San Diego School of Medicine, a diverse team of neuroscientists and surgeons successfully grafted human neural progenitor cells into rhesus monkeys with spinal cord injuries.

27 Feb 2018

Schizophrenia may be related to neurodevelopment changes, study says

Schizophrenia may be related to neurodevelopment changes, including brain's inability to create the appropriate vascular system, according to new study resulted from a partnership between the D'Or Institute for Research and Education, the University of Chile and the Federal University of Rio de Janeiro.

22 Feb 2018

Valproic acid exposure results in characteristics linked to autism, zebrafish study shows

Exposure to a compound used to treat migraines and seizures causes characteristics associated with autism, groundbreaking research with zebrafish has demonstrated.

24 Jan 2018

Discovery may advance stem cell therapies, gene-targeting treatments for neurological diseases

New research from Sanford Burnham Prebys Medical Discovery Institute is among the first to describe how an mRNA modification impacts the life of neural stem cells.