Pancreatic Cancer News and Research

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Pancreatic cancer is the fourth leading cause of all cancer deaths in the United States and the third leading cause of cancer deaths in individuals ages 40 to 60. Approximately 37,000 Americans are diagnosed with pancreatic cancer each year, and, each year, approximately the same number die from it. Often, pancreatic cancer is found too late for surgical intervention, and chemotherapy and radiation treatments have little effect.

Energy waves on cancer cell surfaces linked to tumor growth and aggressiveness

In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine say they have shed new light on the location and function of power-generating waves on the covering, or membrane, of these cells.

9 Jul 2025

EMP1 identified as key driver of tumor progression in resectable pancreatic cancer

The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the associated factor EMP1 in the progression of resectable pancreatic cancer (PC).

4 Jul 2025

Aromatic benzaldehyde inhibits growth of therapy-resistant pancreatic cancer

During therapy, some cancer cells evolve to escape elimination. Newer anticancer drugs that can overcome this resistance are necessary.

2 Jul 2025

Insilico Medicine begins clinical trial for AI-designed cancer drug ISM3412

Insilico Medicine, a clinical-stage biotechnology company driven by generative artificial intelligence (AI), today announces that the first patient has been dosed in a global multicenter clinical trial (NCT06414460) to evaluate ISM3412, a potentially best-in-class, AI-empowered MAT2A inhibitor with novel structure, in patients with locally advanced and metastatic solid tumors.

27 Jun 2025

Rare pancreatic cancer patients show remarkable outcomes with immunotherapy

A new research paper was published in Volume 16 of Oncotarget on June 10, 2025, titled "Exceptional responders to immunotherapy in pancreatic cancer: A multi-institutional case series of a rare occurrence."

17 Jun 2025

Gut microbes offer clues for early detection of pancreatic cancer

Pancreatic cancer is a severe illness and major challenge in cancer medicine since it is difficult to diagnose, while potential therapies are scarce.

12 Jun 2025

New cancer vaccine shows promise against deadly pancreatic tumors

Pancreatic cancer has a five-year survival rate of just 13%, making it the deadliest cancer, according to the American Cancer Society.

11 Jun 2025

Eva1 targeted CAR T cells successfully eliminate tumors in preclinical study

CAR-T cells are specialized immune cells genetically modified to recognize and attack cancer cells. Researchers at Nagoya University in Japan and their collaborators have developed new CAR-T cells to target malignant tumors.

11 Jun 2025

Eliminating stellate cells reduces liver metastasis in mouse models

The prestigious journal Hepatology Communications reports on the discovery by the Cancer and Translational Medicine research group of the University of the Basque Country (EHU).

10 Jun 2025

Ending unnecessary cancer screenings can take over a decade

Stopping the widespread use of unnecessary, potentially even harmful, cancer screenings can take up to 13 years and potentially even longer after new guidelines are put in place, according to a new study.

9 Jun 2025

Switching to a low fat diet slows pancreatic precancer development in mice

Pancreatic cancer is one of the deadliest forms of cancer, killing 87% of patients within five years. Previous studies have shown that obesity can increase pancreatic cancer risk by around 50%.

4 Jun 2025

PCSK9 protein controls how pancreatic cancer cells spread to the lung or liver

A protein called PCSK9 determines how pancreatic cancer cells metastasize to different parts of the body.

4 Jun 2025

How soy and gut microbes alter cancer treatment results

Researchers have discovered that plant-derived phytochemicals and their gut microbiome metabolites control the effectiveness of PI3K inhibitors in cancer therapy. The study reveals that dietary components, especially soy compounds processed by gut bacteria, can alter drug metabolism and impact treatment outcomes.

2 Jun 2025

Muscle wasting in cancer tied to blood vessel dysfunction

A dysfunction in muscle blood vessels could be to blame for the weak muscles and weight loss that most cancer patients experience, according to a new study from University of Illinois Chicago researchers.

29 May 2025

Large global study links higher alcohol intake to increased pancreatic cancer risk

A pooled analysis of over 2.4 million adults across four continents shows a modest but significant increase in pancreatic cancer risk with higher alcohol consumption. The risk is especially pronounced for beer and liquor, and at higher intake levels in men and women.

25 May 2025

New AI blood test tracks pancreatic cancer treatment response

An artificial intelligence technique for detecting DNA fragments shed by tumors and circulating in a patient's blood, developed by Johns Hopkins Kimmel Cancer Center investigators, could help clinicians more quickly identify and determine if pancreatic cancer therapies are working.

22 May 2025