Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Antidepressant use during pregnancy may combine with inflammation to alter offspring neurobiology

Antidepressant use during pregnancy may combine with inflammation to heighten the risk of lifelong neurodevelopmental changes in babies' brains, such as those linked to autism, new research from the University of Virginia School of Medicine suggests.

20 Dec 2022

Long-lived Chilean rodent is a useful model of natural sporadic Alzheimer's Disease

Led by researchers from the University of California at Irvine, a new study reveals that a long-lived Chilean rodent, called Octodon degus (degu), is a useful and practical model of natural sporadic Alzheimer's Disease.

20 Dec 2022

Previous traumatic brain injury may potentially affect frontotemporal dementia risk

A recent study from the University of Eastern Finland shows that previous traumatic brain injury may potentially affect the risk of frontotemporal dementia.

19 Dec 2022

Study provides new insights into the pathology of LATE

Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer's disease or AD (and sometimes co-exists with it), but LATE is a different condition, with its own risks and causes.

16 Dec 2022

Study: People with cluster headaches may be more likely to have other medical conditions

People with cluster headaches may be more than three times more likely to have other medical conditions such as heart disease, mental disorders and other neurologic diseases, according to a study published in the December 14, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

16 Dec 2022

New clue may explain why women are at greater risk for Alzheimer's disease

Scientists at Scripps Research and Massachusetts Institute of Technology (MIT) have found a clue to the molecular cause of Alzheimer's - a clue that may also explain why women are at greater risk for the disease.

15 Dec 2022

Olfactory viral inflammation may accelerate the onset of Alzheimer’s disease

Viruses can inflame and disrupt connections between the olfactory system, which governs the sense of smell, and the part of the brain associated with memory and learning, possibly accelerating the onset of Alzheimer’s disease, according to a new study from researchers at the University of Colorado Anschutz Medical Campus.

15 Dec 2022

Study finds altered spontaneous brain activity in people with Down syndrome

Researchers of the Faculty of Psychology, the Institute of Neurosciences and the Institute of Complex Systems of the University of Barcelona have identified, using functional magnetic resonance techniques, differences in the spontaneous activity of the brain in a resting state in people with Down syndrome (DS) compared to the general population. Also, these variations could be related to cognitive skills.

15 Dec 2022

Flexible assemblies of nerve cells appear to be key to successful episodic memory

For the first time, scientists have recorded human nerve cells firing together in flexible assemblies, a process that appears necessary to successfully encode long-term memories, a study led by UT Southwestern researchers reports.

14 Dec 2022

Study uncovers a new immune culprit in Alzheimer’s disease

The reason your three-pound brain doesn't feel heavy is because it floats in a reservoir of cerebrospinal fluid (CSF), which flows in and around your brain and spinal cord.

13 Dec 2022

People with Alzheimer’s and Down syndrome may benefit from participating in Alzheimer’s clinical trials

Amyloid plaques — protein clumps that are one of the hallmarks of Alzheimer's disease—occur at roughly the same level in the brains of people with Down syndrome who have Alzheimer's as they do in people with forms of hereditary, early-onset Alzheimer's, according to research funded by the National Institutes of Health.

12 Dec 2022

Estrogen replacement therapy may be a tool to mitigate delirium

Delirium is common among women with urinary tract infections (UTIs) - especially those who have experienced menopause.

8 Dec 2022

Researchers receive $11 million NIH grant to evaluate a 5-minute dementia screening tool

Investigators at Albert Einstein College of Medicine, Montefiore Health System, Regenstrief Institute, and Indiana University School of Medicine have received an $11 million grant from the National Institutes of Health to evaluate an Einstein-developed test for assessing cognitive impairment and dementia.

8 Dec 2022

Genetic predisposition to ADHD can predict risk of late-onset Alzheimer's disease

Genetic predisposition to attention-deficit/hyperactivity disorder (ADHD) can predict cognitive decline and Alzheimer's disease later in life, revealed an analysis published today in Molecular Psychiatry by University of Pittsburgh School of Medicine researchers.

8 Dec 2022

Salk researchers shed new light on specific mechanisms that activate oncogenes

Cancer, caused by abnormal overgrowth of cells, is the second-leading cause of death in the world. Researchers from the Salk Institute have zeroed in on specific mechanisms that activate oncogenes, which are altered genes that can cause normal cells to become cancer cells.

7 Dec 2022

Alzheimer's Disease News and Research

Further Reading

Antidepressant use during pregnancy may combine with inflammation to alter offspring neurobiology

Long-lived Chilean rodent is a useful model of natural sporadic Alzheimer's Disease

Previous traumatic brain injury may potentially affect frontotemporal dementia risk

Study provides new insights into the pathology of LATE

Study: People with cluster headaches may be more likely to have other medical conditions

New clue may explain why women are at greater risk for Alzheimer's disease

Olfactory viral inflammation may accelerate the onset of Alzheimer’s disease

Study finds altered spontaneous brain activity in people with Down syndrome

Flexible assemblies of nerve cells appear to be key to successful episodic memory

Study uncovers a new immune culprit in Alzheimer’s disease

People with Alzheimer’s and Down syndrome may benefit from participating in Alzheimer’s clinical trials

Estrogen replacement therapy may be a tool to mitigate delirium

Researchers receive $11 million NIH grant to evaluate a 5-minute dementia screening tool

Genetic predisposition to ADHD can predict risk of late-onset Alzheimer's disease

Salk researchers shed new light on specific mechanisms that activate oncogenes

Study: People with higher levels of vitamin D in the brain have better cognitive function

Oral bacteria may be a contributory factor in patients developing brain abscesses

Chemical residue from commercial dishwashers causes gut epithelial barrier damage

Study identifies optimal blood tests for Alzheimer's detection and disease monitoring

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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