Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Hyperglycemia and adverse pregnancy outcome study (HAPO)

Gestational diabetes may place a much higher percentage of pregnant women -- and their unborn babies -- at risk for adverse outcomes than previously believed, according to a major international study presented at the American Diabetes Association's 67th Annual Scientific Sessions.

23 Jun 2007

Impaired anti-inflammatory response plays role in pathology of type 2 diabetes

Type 2 diabetes is classified as a metabolic disorder, but a growing number of researchers are beginning to think of it also as a disease of the innate immune system. Inflammation, a key component of the early immune response, is chronically elevated in people with type 2 diabetes.

17 Jun 2007

In mice, drug protects against diabetes and atherosclerosis

Blocking a single protein with an experimental drug prevented and treated both type 2 diabetes and atherosclerosis in laboratory mice that had been fed unhealthy diets and were genetically predisposed to these common killers, according to an article published online in Nature.

8 Jun 2007

Researchers to discuss gene that may be linked to polycystic ovary syndrome

Researchers in endocrinology and obstetrics and gynecology at Cedars-Sinai Medical Center will make several presentations at the upcoming annual meetings of two medical organizations , the Androgen Excess Society (June 1, 2007) and the Endocrine Society (June 2-5, 2007).

3 Jun 2007

Macrophages may have role blocking obesity

Macrophages - the scavenger cells of the body's immune system - are known as troublemakers for the role they play in obesity, but Stanford University School of Medicine researchers have found that the cells can also be saviors when it comes to metabolism.

22 May 2007

Merits and risks of postmenopausal hormone therapy

The study was categorized as a primary prevention trial for coronary heart disease, although the fact that mean age at recruitment was 63 years was not given enough importance at that time. WHI investigators concluded that hormone therapy (HT) was not cardioprotective, and, in fact, its riskbenefit ratio did not favor the use of postmenopausal hormones for prevention of chronic diseases.

17 May 2007

Epidemiology of obesity, pathophysiology, associated disease and management

Due to the gastrointestinal tract's role in body weight regulation, gastroenterologists should work closely with other medical disciplines to oversee and coordinate the care of obese individuals, according to an American Gastroenterological Association (AGA) Institute Obesity Task Force Report.

15 May 2007

Omega-3 fatty acids from fish oil may prevent the loss of muscle mass in older people

A research team led by Carole Thivierge, from Universit Laval's Institute of Nutraceutics and Functional Foods, shows that omega-3 fatty acids from fish oil have a positive effect on the metabolism of muscle proteins.

10 May 2007

Plant chemical harmine fights diabetes in mice

After screening hundreds of compounds for their effects on fat development, researchers have discovered that an ingredient found in some plants fights diabetes in mice without some of the side effects attributed to other antidiabetes drugs.

9 May 2007

Nutrient "floodgate" protects against inflammatory immune response

After every meal, the body must prevent the immune system from launching an all-out fight against food.

4 May 2007

Laparoscopic gastric banding surgery improves insulin resistance

A new study examining the overall and gender-related effects of laparoscopic gastric banding surgery (LGBS) on insulin resistance, body composition, and metabolic risk markers six months post-surgery has found significant improvements in insulin resistance.

2 May 2007

Big win in the battle against diabetes

In newly published research scientists have revealed that they have discovered more genes linked to Type 2 Diabetes.

29 Apr 2007

How your food is cooked may be as important to your health as the food itself

Researchers now know more about a new class of toxins that might soon become as important a risk factor for heart disease and metabolic disorders as trans fats.

25 Apr 2007

Striking parallelism between humans and horses when it comes to obesity

Horses are inheritably couch potatoes. An overeating, slothful horse leads to an obese horse. Unlike humans, however, horse owners often don't see the dangers of an obese horse.

25 Apr 2007

HIV linked to increased risk of heart attack

Researchers from Massachusetts General Hospital (MGH) have found that infection with HIV, the virus that causes AIDS, is also associated with increased risk of myocardial infarction or heart attack.

25 Apr 2007

Impaired intestinal metabolic function plays a critical role in the development of cardiovascular disease

Nutritional scientists at the University of Alberta are the first to establish a connection between high insulin levels and dysfunction of intestinal lipid metabolism in an animal model.

25 Apr 2007

Steam, boil, stew for food preparation

How your food is cooked may be as important to your health as the food itself. Researchers now know more about a new class of toxins that might soon become as important a risk factor for heart disease and metabolic disorders as trans fats.

25 Apr 2007

Extended bed rest leads to substantial muscle deterioration in older adults

Extended bed rest – often necessary during hospitalization – leads to a substantial amount of muscle deterioration in older adults, researchers at the University of Arkansas for Medical Sciences (UAMS) report in the April 25 issue of the Journal of the American Medical Association .

25 Apr 2007

Twin studies identify genes that influence human health in unexpected ways

Daniel O'Connor, M.D., Professor of Medicine and Pharmacology at the University of California, San Diego (UCSD) School of Medicine has studied about 265 twin pairs over the past few years, which has led him to some surprising discoveries.

18 Apr 2007

Insulin receptors play a critical role in promoting islet growth

A new Joslin-led study has identified the insulin receptor as an important protein that promotes islet cell growth in mice whose bodies are unable to use insulin properly, or are insulin resistant, a precursor to type 2 diabetes.

4 Apr 2007