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Well-known cancer drugs may prevent SARS-CoV-2 viral replication say researchers

Researchers in Frankfurt, Germany, have described cell signaling events that occur when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells and have identified pathways that are essential for the virus to replicate.

17 May 2020

South Africa obtains first laboratory isolate of SARS-CoV-2

While much of the scientific and medical community rushes to develop therapeutic agents for COVID-19 based on clinical data, getting a better understanding of the brand-new virus remains crucial.

11 May 2020

COVID-19 could accelerate activation of dormant tuberculosis (TB)

The ongoing COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has thrown much of the world into disarray, with over 4 million people reported infected and well over 282,000 deaths. A new study published on the preprint server bioRxiv in May 2020 suggests that the long-term impact of the virus could include activation of dormant bacterial infections like tuberculosis (TB).

10 May 2020

UCD researcher awarded €500,000 SFI Future Innovator Prize for innovative imaging solution

Ireland's Minister for Business, Enterprise, and Innovation, Heather Humphreys, TD, has today announced that a special Science Foundation Ireland Future Innovator Prize of €500,000 has been granted to University College Dublin researcher, Professor Dominic Zerulla.

9 May 2020

Study: Genes may play a far more complex role in oocyte maturation than previously assumed

Over the last six years a group of Estonian geneticists led by Associate Professor Agne Velthut-Meikas and a PhD student Ilmatar Rooda from TalTech Department of Chemistry and Biotechnology have studied genes previously associated primarily with female hormone synthesis and ovarian follicle development.

7 May 2020

Interleukin-12 electroporation led to clinical responses in patients with advanced melanoma

Combining intratumoral electroporation of interleukin-12 (IL-12) DNA (tavokinogene telseplasmid, or TAVO) with the immune checkpoint inhibitor pembrolizumab (Keytruda) led to clinical responses in patients with immunologically quiescent advanced melanoma, according to results from a phase II trial.

6 May 2020

Sartorius launches the new Incucyte SX5® for live-cell analysis, offering new possibilities for live-cell analysis experiments

Sartorius, a leading international supplier for the biopharmaceutical industry, today launched the new Incucyte SX5 Live-Cell Analysis System, the latest in the company’s line of live-cell analysis products.

From Sartorius 5 May 2020

AM and 3D printing communities rally together to fight against COVID-19

The rapid proliferation of COVID-19 has been putting great strain on healthcare systems across the world, with demand for critical medical equipment and supplies mounting.

30 Apr 2020

Breastfeeding helps reduce the risk of maternal postpartum diabetes

A team of South Korean researchers found that lactation can lower the incidence and reduce the risk of maternal postpartum diabetes.

29 Apr 2020

Study unravels mechanisms responsible for postnatal skin expansion

In adult tissue, the number of cells in each tissues and organs remains constant, and any new cells produced by cell division need to be compensated by the loss of other cells.

29 Apr 2020

How toxic are chloroquine and hydroxychloroquine to cells?

The spread of the pandemic disease COVID-19 caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has now reached almost every country of the world, with over 3.11 million cases and over 217,000 deaths as of April 29, 2020.

29 Apr 2020

Immunotherapy before surgery may help eradicate high-risk breast cancer

A new study led by Yale Cancer Center researchers shows women with high-risk HER2-negative breast cancer treated before surgery with immunotherapy, plus a PARP inhibitor with chemotherapy, have a higher rate of complete eradication of cancer from the breast and lymph nodes compared to chemotherapy alone.

28 Apr 2020

Study marks a major step towards beta cell replacement therapy

The loss of insulin-secreting beta cells by autoimmune destruction leads to type 1 diabetes. Clinical islet cell transplantation has the potential to cure diabetes, but donor pancreases are rare.

28 Apr 2020

Spaceflight causes key changes in cultured heart cells

Spaceflight changes much about the human body, including how the heart functions and how cells that create heart tissue behave. Scientists studying these changes on the International Space Station continue to report important discoveries.

27 Apr 2020

Combinations of PAC and WFA are highly synergistic against proliferation of non-small cell lung cancer

Oncotarget Volume 11 Issue 16 showed that the sensitivity of H1299 and A549 cells to concomitant treatment with PAC and WFA was greater than that of either PAC or WFA alone.

23 Apr 2020

Researchers demonstrate how TB bacteria import vitamin B12 molecules to grow

Researchers from Russia, the Netherlands, Sweden, and the U.S. have revealed the structure of the protein responsible for vitamin B12 import into the cells of the bacterium that causes tuberculosis. The research findings were published in Nature.

23 Apr 2020

Scientists find gene signature for poor response to standard therapy in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

Study shows how tumor cells respond to lack of nutrients

Some solid tumors have a very high growth rate, which often leads to a lack of vascularization due to the impossibility to develop, at the same time, the blood vessels that accompany and nourish it.

21 Apr 2020

Discovery could open door to the development of new anti-cancer drugs

A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer.

20 Apr 2020

Activating a braking mechanism against cancer

A team has identified the binding site where drug compounds could activate a braking mechanism against runaway growth of cancer.

20 Apr 2020

Proliferation News and Research

Well-known cancer drugs may prevent SARS-CoV-2 viral replication say researchers

South Africa obtains first laboratory isolate of SARS-CoV-2

COVID-19 could accelerate activation of dormant tuberculosis (TB)

UCD researcher awarded €500,000 SFI Future Innovator Prize for innovative imaging solution

Study: Genes may play a far more complex role in oocyte maturation than previously assumed

Interleukin-12 electroporation led to clinical responses in patients with advanced melanoma

Sartorius launches the new Incucyte SX5® for live-cell analysis, offering new possibilities for live-cell analysis experiments

AM and 3D printing communities rally together to fight against COVID-19

Breastfeeding helps reduce the risk of maternal postpartum diabetes

Study unravels mechanisms responsible for postnatal skin expansion

How toxic are chloroquine and hydroxychloroquine to cells?

Immunotherapy before surgery may help eradicate high-risk breast cancer

Study marks a major step towards beta cell replacement therapy

Spaceflight causes key changes in cultured heart cells

Combinations of PAC and WFA are highly synergistic against proliferation of non-small cell lung cancer

Researchers demonstrate how TB bacteria import vitamin B12 molecules to grow

Scientists find gene signature for poor response to standard therapy in rare uterine cancer

Study shows how tumor cells respond to lack of nutrients

Discovery could open door to the development of new anti-cancer drugs

Activating a braking mechanism against cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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