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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

US scientists develop new technique to track the progression of cancer

US scientists have developed a new technique that allows them to track the progression of a person's cancer by uncovering changes in their tumour's genetic material.

19 Feb 2010

$Caliper Life Sciences introduces automated nucleic acid fractionation instrument, LabChip XT$

Caliper Life Sciences introduces automated nucleic acid fractionation instrument, LabChip XT

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery and life sciences research, today introduced the LabChip XT, an automated nucleic acid fractionation instrument.

19 Feb 2010

Variations among individual organisms attributed to differences in genes, environment or chance

Biologists attribute variations among individual organisms to differences in genes or environment, or both. But a new study of nematode worms with identical genes, raised in identical environments, has revealed another factor: chance.

19 Feb 2010

Cancer genomes: Distinguishing between 'driver' and 'passenger' mutations

A new study of mutations in cancer genomes shows how researchers can begin to distinguish the 'driver' mutations that push cells towards cancer from the 'passenger' mutations that are a by-product of cancer cell development. The study also shows that at least one in nine genes can be removed without killing human cells.

19 Feb 2010

Micro Imaging Technology becomes Micro Identification Technologies

Micro Imaging Technology, Inc. today announced that it has changed is company name to Micro Identification Technologies to better reflect the extensive capabilities of its ID technology software.

19 Feb 2010

Most genetic abnormalities shared across multiple cancers

An international team of researchers has created a genome-scale map of 26 different cancers, revealing more than 100 genomic sites where DNA from tumors is either missing or abnormally duplicated compared to normal tissues. The study, the largest of its kind, finds that most of these genetic abnormalities are not unique to one form of cancer, but are shared across multiple cancers. The work appears in the February 18 issue of the journal Nature.

19 Feb 2010

Emerging concepts from gene regulation studies in immune cells

The seventh meeting in the “Emergence and Convergence” series jointly organized by La Fondation IPSEN and Nature brings together today in San Antonio (Texas, USA) leading experts to discuss concepts emerging from gene regulation studies in immune cells that have led to insights into the initiation and maintenance of epigenetic chromatin marks necessary for proper differentiation and function of these cells in the immune system.

19 Feb 2010

Mechanism by which Plasmodium replicates itself in human blood to spread disease identified

Malaria remains one of the most deadly infectious diseases. Yet, how Plasmodium, the malaria parasite, regulates its infectious cycle has remained an enigma despite decades of rigorous research.

19 Feb 2010

Study shows how genes and environmental factors influence common human diseases

A UCLA study reveals how human genes interact with their environment to boost disease risk. Published in the Feb. 18 online edition of the American Journal of Human Genetics, the findings shed light on why the search for specific gene variants linked to human diseases can only partly explain common disorders.

19 Feb 2010

Researchers use Life Technologies’ next-generation sequencing instruments for cancer research

Life Technologies Corporation today announced the publication of two key scientific papers that highlight the utility of next-generation sequencing instruments in better understanding disease and the genetic differences that cause diversity within and between human populations. The Applied Biosystems SOLiD™ System was used in both of these research studies.

19 Feb 2010

VIRxSYS announces results from prophylactic HIV vaccine study at 2010 CROI conference

VIRxSYS Corporation, a privately held company developing vaccines and RNA therapies for serious human diseases such as HIV and cardiovascular diseases, announced results from its prophylactic HIV vaccine (VRX1023) study in Rhesus Macaque monkeys during a presentation today at the 2010 Annual Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco, CA.

19 Feb 2010

ATM tumor-suppressor also recognizes damage caused by ROS and orders autophagy

ATM, a protein that reacts to DNA damage by ordering repairs or the suicide of the defective cell, plays a similar, previously unknown role in response to oxidative damage outside of the nucleus, researchers report this week in the online version of the Proceedings of the National Academy of Sciences.

19 Feb 2010

Johns Hopkins Kimmel Cancer Center scientists develop genome-based blood tests for cancer

Scientists at the Johns Hopkins Kimmel Cancer Center have used data from the whole genome sequencing of cancer patients to develop individualized blood tests they believe can help physicians tailor patients' treatments. The genome-based blood tests, believed to be the first of their kind, may be used to monitor tumor levels after therapy and determine cancer recurrence.

19 Feb 2010

Cellular metabolism plays a key role in cancer development

It is not unusual to hear people blame their metabolism after gaining a few pounds. But changes in metabolism - the process that shapes how our bodies turn food into energy -- can have much more sinister effects than making it hard to fit into your favorite jeans.

19 Feb 2010

RainDance Technologies enters into strategic agreement with Applied Biosystems

RainDance Technologies, Inc., a leading provider of innovative microdroplet-based solutions for human health and disease research, and Applied Biosystems, part of Life Technologies Corporation, announced today they have entered into a strategic agreement to co-market the first solution that combines microdroplet PCR-based sequence enrichment with next-generation sequencing.

19 Feb 2010

GeoVax Labs presents results of preclinical study on prototype HIV/AIDS vaccine at CROI

GeoVax Labs, Inc., an Atlanta-based, biopharmaceutical company developing vaccines for diseases caused by HIV-1 (Human Immunodeficiency Virus), today announced that it presented the results of a preclinical study on a prototype HIV/AIDS vaccine at the Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco.

18 Feb 2010

IRA to offer Personal Genetic Health and Ancestry Testing to residents of Latin America

Pathway Genomics™ (www.PATHWAY.com), a privately held, venture-backed company today announced that the Instituto de Referencia Andino (IRA), a Clinical Laboratory and Division of Rochem Biocare will offer Personal Genetic Health and Ancestry Testing to residents of Latin America.

18 Feb 2010

AGBT meeting: Study workshop on complete genome sequencing for human disease

Complete Genomics Inc., a third-generation human genome sequencing company, today announced that it will be unveiling some of its highly anticipated customer results at the 11th annual Advances in Genome Biology and Technology (AGBT) meeting to be held in Marco Island, Fla., Feb. 24-27, 2010.

18 Feb 2010

Norwegian government task force suggests formation of single company to commercialise biomaterial assets

Having studied the ethical, judicial and political arguments, the Norwegian government task force has suggested that a single nationwide company should be formed to commercialise biomaterials assets from the country’s various sources. The task force has also recommended HUNT Biosciences be a model for the national company.

18 Feb 2010

HPV DNA testing vital in identification of cervical cancer

Roche Molecular Systems, Inc. announced today that preliminary data from its ATHENA (Addressing THE Need for Advanced HPV Diagnostics) trial support the importance of screening for human papillomavirus (HPV) genotypes that put women at highest risk for developing cervical cancer. ATHENA is a prospective, double-blind, multi-centered, 47,000-patient, U.S.-registration trial designed to demonstrate the effectiveness of HPV detection as part of a cervical cancer screening program.

18 Feb 2010

DNA News and Research

Further Reading

US scientists develop new technique to track the progression of cancer

Caliper Life Sciences introduces automated nucleic acid fractionation instrument, LabChip XT

Variations among individual organisms attributed to differences in genes, environment or chance

Cancer genomes: Distinguishing between 'driver' and 'passenger' mutations

Micro Imaging Technology becomes Micro Identification Technologies

Most genetic abnormalities shared across multiple cancers

Emerging concepts from gene regulation studies in immune cells

Mechanism by which Plasmodium replicates itself in human blood to spread disease identified

Study shows how genes and environmental factors influence common human diseases

Researchers use Life Technologies’ next-generation sequencing instruments for cancer research

VIRxSYS announces results from prophylactic HIV vaccine study at 2010 CROI conference

ATM tumor-suppressor also recognizes damage caused by ROS and orders autophagy

Johns Hopkins Kimmel Cancer Center scientists develop genome-based blood tests for cancer

Cellular metabolism plays a key role in cancer development

RainDance Technologies enters into strategic agreement with Applied Biosystems

GeoVax Labs presents results of preclinical study on prototype HIV/AIDS vaccine at CROI

IRA to offer Personal Genetic Health and Ancestry Testing to residents of Latin America

AGBT meeting: Study workshop on complete genome sequencing for human disease

Norwegian government task force suggests formation of single company to commercialise biomaterial assets

HPV DNA testing vital in identification of cervical cancer

Understanding the DNA Damage Response in Innate Immunity eBook

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