Central Nervous System News and Research

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Researchers use novel PET tracer to assess myelin damage in mouse models of MS

The loss or damage of myelin, a cellular sheath that surrounds and insulates nerves, is the hallmark of the immune-mediated neurological disorder multiple sclerosis.

12 Jan 2018

Study finds overall pattern of commonality between Huntington's and Parkinson's

A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, despite being two very distinct diseases.

12 Jan 2018

The Virus That Causes Hand, Foot and Mouth Disease May Use Human Protein to Aid Infection

The human protein, prohibitin, may be used by the virus to enter motor neurons and cause the neurological complications of hand, foot and mouth disease.

12 Jan 2018

UCLA scientists coax human stem cells to become sensory interneurons

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have, for the first time, coaxed human stem cells to become sensory interneurons -- the cells that give us our sense of touch.

11 Jan 2018

Kessler Foundation researcher receives grant for study on emotional processing intervention in MS

Helen Genova, PhD, Assistant Director of Neuropsychology & Neuroscience Research at Kessler Foundation, has been awarded a $44,000 grant from the National Multiple Sclerosis Society.

10 Jan 2018

Regeneron forms consortium to accelerate largest widely-available human sequencing resource

By the end of 2019, Regeneron plans to sequence the exomes of all 500,000 people within the UK Biobank resource, all with associated health records, creating an unprecedented resource linking human genetic variations to human biology and disease.

9 Jan 2018

Important facts to know about Lyme disease and anesthesia

An article in the American Association of Nurse Anesthetists's AANA Journal, "Lyme Disease and Anesthesia Considerations," discusses possible effects of anesthesia on Lyme disease patients undergoing surgery.

8 Jan 2018

Sleeping sickness actually caused by acceleration of biological clocks

Sleeping sickness could use a more encompassing moniker. An international study from the O'Donnell Brain Institute shows one of Africa's most lethal diseases is actually a circadian rhythm disorder caused by the acceleration of biological clocks controlling a range of vital functions besides sleep.

4 Jan 2018

Researchers optimize method to increase resolution of proteomic analysis

One of the key challenges of proteomics, the study of all proteins expressed by a cell or organism, is managing to distinguish between molecules that are structurally different yet have the same mass.

4 Jan 2018

Experts report new guidelines for clinical trial design in patients with brain metastases

Clinical trials of new anti-cancer therapies have often excluded patients whose disease has spread to the brain or central nervous system (CNS) or, if such patients were allowed on trial, trials have often failed to clearly capture information on the drug's effect in the brain.

30 Dec 2017

UCLA study reveals positive effects of estrogen treatment in people with MS

A study by UCLA researchers reveals the cellular basis for how the hormone estrogen protects against damage to the central nervous system in people with multiple sclerosis (MS).

28 Dec 2017

Updated ‘McDonald Criteria’ expected to improve speed and accuracy of MS diagnosis

The McDonald Criteria for the Diagnosis of Multiple Sclerosis have just been revised by a 30-member international panel of MS experts co-chaired by Jeffrey Cohen, MD (Cleveland Clinic) and Alan Thompson, MD (University College London).

22 Dec 2017

Folic acid supplementation during late pregnancy may increase risk of allergies in offspring

A new study suggests that taking folic acid in late pregnancy may increase the risk of allergies in offspring affected by intrauterine growth restriction.

21 Dec 2017

Study finds racial, socioeconomic barriers to accessing life-saving treatment for metastatic cancer

Increasing use of a potentially life-saving treatment for metastatic cancer is leaving too many vulnerable patients behind, according to a new study from Yale Cancer Center/Smilow Cancer Hospital published in JNCCN – Journal of the National Comprehensive Cancer Network.

19 Dec 2017

Researchers identify novel mechanism that protects from brain tumor

A group of researchers at the Spanish National Cancer Research Centre have identified a protein called RanBP6 as a new regulator of EGFR. In a paper published in Nature Communications they show how silencing of RanBP6 promoted glioma growth, by upregulating EGFR expression.

18 Dec 2017

Mosquito-infected monkeys may provide better understanding of Zika transmission routes

Monkeys who catch Zika virus through bites from infected mosquitoes develop infections that look like human Zika cases, and may help researchers understand the many ways Zika can be transmitted.

14 Dec 2017

Study provides new insights into development of Sonic Hedgehog medulloblastoma

Medulloblastoma is the most common type of solid brain tumor in children. Current treatments offer limited success and may leave patients with severe neurological side effects, including psychiatric disorders, growth retardation and cognitive impairment.

13 Dec 2017

Cellular self-digestion process plays role in development of autoimmune diseases

Autophagy allows cells to degrade and recycle their cellular components. Researchers at UZH have now demonstrated that the autophagy machinery in certain immune cells leads to the immune system attacking the central nervous system.

13 Dec 2017

Tapeworm drug could provide new hope for patients with Parkinson's disease

Researchers at Cardiff University, in collaboration with the University of Dundee, have identified a drug molecule within a medicine used to treat tapeworm infections which could lead to new treatments for patients with Parkinson's disease.

12 Dec 2017

Study: Unusual neuroinflammation may underlie cognitive problems in cART-treated HIV patients

Although combination antiretroviral therapy (cART) has improved survival of patients infected with HIV and has reduced the incidence of severe neurologic complications, almost half of cART-treated HIV patients experience some degree of neurocognitive impairment (neuroHIV).

8 Dec 2017

Central Nervous System News and Research

Researchers use novel PET tracer to assess myelin damage in mouse models of MS

Study finds overall pattern of commonality between Huntington's and Parkinson's

The Virus That Causes Hand, Foot and Mouth Disease May Use Human Protein to Aid Infection

UCLA scientists coax human stem cells to become sensory interneurons

Kessler Foundation researcher receives grant for study on emotional processing intervention in MS

Regeneron forms consortium to accelerate largest widely-available human sequencing resource

Important facts to know about Lyme disease and anesthesia

Sleeping sickness actually caused by acceleration of biological clocks

Researchers optimize method to increase resolution of proteomic analysis

Experts report new guidelines for clinical trial design in patients with brain metastases

UCLA study reveals positive effects of estrogen treatment in people with MS

Updated ‘McDonald Criteria’ expected to improve speed and accuracy of MS diagnosis

Folic acid supplementation during late pregnancy may increase risk of allergies in offspring

Study finds racial, socioeconomic barriers to accessing life-saving treatment for metastatic cancer

Researchers identify novel mechanism that protects from brain tumor

Mosquito-infected monkeys may provide better understanding of Zika transmission routes

Study provides new insights into development of Sonic Hedgehog medulloblastoma

Cellular self-digestion process plays role in development of autoimmune diseases

Tapeworm drug could provide new hope for patients with Parkinson's disease

Study: Unusual neuroinflammation may underlie cognitive problems in cART-treated HIV patients

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