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NIH awards $1.8 million grant for brain imaging technique

A researcher at the Cockrell School of Engineering at The University of Texas at Austin has received a four-year, $1.8 million grant from the National Institutes of Health (NIH) to develop a new technique for imaging blood flow across the surface of the brain that could help patients undergoing neurosurgery.

24 Jun 2015

Targeted molecular-imaging method could help identify early stages of prostate cancer

A targeted molecular-imaging method under development at Rochester Institute of Technology could help detect early stages of prostate cancer and improve image-directed biopsies.

23 Jun 2015

Near-infrared imaging techniques for visualization of cartilage tissue

The mainstream techniques for visualization of cartilage tissue in the body are magnetic resonance imaging and computer tomography, but both techniques do not provide optimum quality images.

22 Jun 2015

Nanoplatform technology that detects early stages of cancer receives U.S. patent

A U.S. patent has been awarded to a Kansas State University technology that quickly detects the early stages of cancer before physical symptoms ever appear.

17 Jun 2015

Researchers create cell lines to study gene expression in precursor brown fat and white fat cells

Since the 2009 discovery that energy-burning brown fat can be active in adults, research has raced ahead to understand this tissue and exploit it to treat the epidemic of obesity. Active brown fat also may assist in directly easing the burden of diabetes and related metabolic diseases by lowering the levels of glucose and fatty acids in the bloodstream. But progress in studying human brown fat often has been slowed by difficulties in obtaining and studying samples of the human cells that develop into brown fat.

17 Jun 2015

VENTANA ALK (D5F3) CDx Assay receives FDA approval

Ventana Medical Systems, Inc., a member of the Roche Group, today announced approval of the VENTANA ALK (D5F3) CDx Assay by the US Food and Drug Administration as a companion diagnostic to aid in the identification of patients for Pfizer's FDA approved targeted therapy, XALKORI (crizotinib).

15 Jun 2015

Study on how maternal proteins help regulate initial cell divisions during early development

Researchers in the University of Georgia's Regenerative Bioscience Center are visually capturing the first process of chromosome alignment and separation at the beginning of mouse development. The findings could lead to answers to questions concerning the mechanisms leading to birth defects and chromosome instability in cancer cells.

10 Jun 2015

OGT launches new arrays for developmental disorders at ESHG

Oxford Gene Technology (OGT), The Molecular Genetics Company, is today launching a new range of arrays at the European Society of Human Genetics (ESHG) Conference in Glasgow, UK, that are dedicated to elucidating the underlying causes of developmental delay.

From Oxford Gene Technology 10 Jun 2015

UC Davis funds BRAIN-STIM program to uncover potential treatments for neurodegenerative disorders

In 2013, President Obama announced the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, unveiling plans to make a bold investment to understand the human mind with the intent to uncover ways to prevent, treat and cure brain disorders like Alzheimer's, autism, and epilepsy.

9 Jun 2015

Cell fusion triggers multiple genetic changes that convert normal cells to cancer cells

Although there is no one established universal cause of cancer, genetic changes are central to its development. The accumulation of spontaneous genetic changes, or mutations, that occur when cells divide can be hastened by exposure to carcinogens such as cigarette smoke (lung cancer) and infectious agents such as the papillomavirus (cervical cancer).

9 Jun 2015

New JIC research helps to settle important debate on epigenetic inheritance

New research findings by John Innes Centre scientists have helped to settle an important debate in the field of epigenetic inheritance. Using the flowering plant Arabidopsis thaliana as a model for their research, Professor Martin Howard, Professor Caroline Dean and members of their labs, have been trying to understand how organisms 'remember' past events at the cellular level.

4 Jun 2015

Portable microendoscope could eliminate need for costly biopsies for esophageal cancer patients

In a clinical study of patients in the United States and China, researchers found that a low-cost, portable, battery-powered microendoscope developed by Rice University bioengineers could eventually eliminate the need for costly biopsies for many patients undergoing standard endoscopic screening for esophageal cancer.

3 Jun 2015

Clinical utility of Caris Molecular Intelligence in five studies to be presented at ASCO 2015

Caris Life Sciences, a leading biotechnology company focused on fulfilling the promise of precision medicine, today announced the presentation of data from five studies that demonstrate the clinical utility of Caris Molecular Intelligence®, the company's panomic comprehensive tumor profiling service, in helping to identify targeted treatment options for patients with rare and/or aggressive tumors.

1 Jun 2015

Caris Molecular Intelligence allows comparisons between tumors sharing histological features

Caris Life Sciences, a leading biotechnology company focused on fulfilling the promise of precision medicine, today announced the presentation of data from three studies that demonstrate the utility of Caris Molecular Intelligence®, the company's panomic comprehensive tumor profiling service, in facilitating comparisons between tumors that share histological features.

1 Jun 2015

Penn researchers to present clinical data at 2015 ASCO Annual Meeting

Researchers from the Abramson Cancer Center of the University of Pennsylvania and Penn's Perelman School of Medicine will present results from several clinical trials and other key studies during the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting from May 29 through June 2.

30 May 2015

Excelitas Technologies announces launch of X-Cite 120LEDmini for fluorescence illumination solutions

Excelitas Technologies Corp., a global technology leader focused on delivering innovative, customized photonic solutions, today announces the X-Cite 120LEDmini – a compact white light LED source for fluorescence imaging applications. Through direct coupling, the X-Cite 120LEDmini provides efficient optical output, exceptional uniformity, and the highest performing coupling optics available.

30 May 2015

High CIP2A may guide TKI choice for chronic phase CML

Treatment with a second-generation tyrosine kinase inhibitor prevents progression to blast crisis in chronic myeloid leukaemia patients with high levels of cancerous inhibitor of PP2A, research suggests.

29 May 2015

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

CQDM, Brain Canada and the Ontario Brain Institute award close to $8.5M to six (6) multi-disciplinary and multi-provincial research teams across Canada to address unmet needs in neuroscience within their Focus on Brain strategic initiative. To this amount, $1.5M is added from the various research entities involved as in-kind contributions.

27 May 2015

Toronto researchers design simple chip for faster, easier detection of antibiotic-resistant bacteria

We live in fear of 'superbugs': infectious bacteria that don't respond to treatment by antibiotics, and can turn a routine hospital stay into a nightmare. A 2015 Health Canada report estimates that superbugs have already cost Canadians $1 billion, and are a "serious and growing issue." Each year two million people in the U.S. contract antibiotic-resistant infections, and at least 23,000 people die as a direct result.

27 May 2015

Study reveals molecular basis for endocrine therapy-resistant breast cancer

Mitsuyoshi Nakao, Director of the Institute of Molecular Embryology and Genetics in Kumamoto University and Associate Professor Noriko Saitoh revealed that a cluster of defined, non-coding RNAs are mechanistically involved in endocrine therapy resistance in human breast cancer cells. Furthermore, resveratrol, a kind of polyphenol, was found to repress these RNAs and inhibit the proliferative activity of breast cancer cells which had acquired resistance.

27 May 2015

Fluorescence News and Research

NIH awards $1.8 million grant for brain imaging technique

Targeted molecular-imaging method could help identify early stages of prostate cancer

Near-infrared imaging techniques for visualization of cartilage tissue

Nanoplatform technology that detects early stages of cancer receives U.S. patent

Researchers create cell lines to study gene expression in precursor brown fat and white fat cells

VENTANA ALK (D5F3) CDx Assay receives FDA approval

Study on how maternal proteins help regulate initial cell divisions during early development

OGT launches new arrays for developmental disorders at ESHG

UC Davis funds BRAIN-STIM program to uncover potential treatments for neurodegenerative disorders

Cell fusion triggers multiple genetic changes that convert normal cells to cancer cells

New JIC research helps to settle important debate on epigenetic inheritance

Portable microendoscope could eliminate need for costly biopsies for esophageal cancer patients

Clinical utility of Caris Molecular Intelligence in five studies to be presented at ASCO 2015

Caris Molecular Intelligence allows comparisons between tumors sharing histological features

Penn researchers to present clinical data at 2015 ASCO Annual Meeting

Excelitas Technologies announces launch of X-Cite 120LEDmini for fluorescence illumination solutions

High CIP2A may guide TKI choice for chronic phase CML

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

Toronto researchers design simple chip for faster, easier detection of antibiotic-resistant bacteria

Study reveals molecular basis for endocrine therapy-resistant breast cancer

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