Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

Researchers evaluated the concurrent colonization of fungi in the nasopharynx of severe COVID-19 patients.

28 Oct 2022

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Johns Hopkins Medicine researchers say they have successfully used a cell's natural process for making proteins to "slide" genetic instructions into a cell and produce critical proteins missing from those cells.

28 Oct 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

Researchers find a switch to regulate the diabetes-causing gene

Researchers at the Centre for Genomic Regulation and Imperial College London have found a switch that regulates the activity of a gene that causes diabetes.

27 Oct 2022

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

A fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.

27 Oct 2022

How important is sterilizing immunity in protection against SARS-CoV-2?

The authors discussed the underlying principles of sterilizing immunity and its importance in protecting individuals against SARS-CoV-2 reinfections during the COVID-19 pandemic.

26 Oct 2022

Exploring new therapeutic targets and biomarkers for neurodegenerative disorders

In this interview, Dr. Shebna Massey discusses neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and more. She also discusses and explores new therapeutic targets and biomarkers for these diseases.

From Sino Biological Inc. 26 Oct 2022

New diagnostic method applies machine learning to advanced genomics data to detect sepsis

Sepsis, the overreaction of the immune system in response to an infection, causes an estimated 20% of deaths globally and as many as 20 to 50% of U.S. hospital deaths each year.

24 Oct 2022

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

Researchers developed integrated host-microbe plasma metagenomics to facilitate sepsis diagnosis.

24 Oct 2022

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Researchers gathered empirical evidence that past pandemics due to infectious pathogens shaped the present-day susceptibility of humans to diseases, such as autoimmune diseases.

24 Oct 2022

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 6 (ORF6) protein contributes to viral pathogenesis and modulates the host's immune responses.

23 Oct 2022

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Researchers assess the role of neutrophil extracellular traps (NETs) in systemic autoimmune and autoinflammatory disorders.

23 Oct 2022

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Researchers examine neutralizing antibody responses against SARS-CoV-2 in elderly individuals who received one mRNA booster dose.

23 Oct 2022

Study reveals TBX20 as a vital regulator of direct human cardiac reprogramming

Mammalian hearts have almost no ability to grow new heart muscle cells, called cardiomyocytes, after birth. Thus, dead tissue after an adult heart attack is not repaired with new cardiomyocytes.

21 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

In a recent study published in the journal eLife, researchers showed the utility of machine-learning models in identifying early immune signatures, which could reliably predict clinical and immunological outcomes in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected outpatients.

20 Oct 2022

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Stem cell-derived neurons from combat veterans with post-traumatic stress disorder (PTSD) react differently to a stress hormone than those from veterans without PTSD, a finding that could provide insights into how genetics can make someone more susceptible to developing PTSD following trauma exposure.

20 Oct 2022

Gene Expression News and Research

Further Reading

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers find a switch to regulate the diabetes-causing gene

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

How important is sterilizing immunity in protection against SARS-CoV-2?

Exploring new therapeutic targets and biomarkers for neurodegenerative disorders

New diagnostic method applies machine learning to advanced genomics data to detect sepsis

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Study reveals TBX20 as a vital regulator of direct human cardiac reprogramming

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Male mice three times more likely than females to survive E. coli infection

Scientists develop new tool to monitor brain plasticity

Salk's three collaborative projects win 2022 Curebound Discovery Grant

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Latest eBooks

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy