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Oral version of remdesivir could extend its reach and benefits to COVID-19 patients

Scientists at the University of North Carolina at Chapel Hill are testing a new route for remdesivir, a pill form of the COVID-19 treatment that’s given to half of all hospitalized patients with the disease.

22 Mar 2022

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

Researchers performed an in situ analysis to evaluate the correlation between CD48 expression and COVID-19.

22 Mar 2022

Antimalarial drugs are also effective at treating a pulmonary disease, study finds

A research team at Colorado State University has discovered that drugs used to treat malaria are also effective at treating a pulmonary disease similar to tuberculosis.

21 Mar 2022

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

The immune system deteriorates with age, making COVID-19 particularly deadly in older people - but to date, no clinically available medication addresses this key risk factor.

21 Mar 2022

IU researchers exploring new ways to treat seasonal or intermittent asthma

Researchers from Indiana University School of Medicine Department of Microbiology and Immunology are studying new ways to treat seasonal or intermittent asthma.

21 Mar 2022

SARS-CoV-2 infection found to reduce fetal lung volume as assessed by MRI

Researchers evaluated the impact of SARS-CoV-2 infection in gestational women on fetal pulmonary development using magnetic resonance imaging.

21 Mar 2022

Study evaluates COVID-19 vaccination with recombinant accessory protein-deficient SARS-CoV-2

Researchers assessed the impact of recombinant accessory protein-deficient severe acute respiratory syndrome coronavirus 2 immunization against SARS-CoV-2 transmission and disease severity.

18 Mar 2022

Hypoxia-inducible factors and SARS-CoV-2 manifestations

Researchers assessed the role of hypoxia-inducible factors in SARS-CoV-2 infection, respiratory symptoms, and epithelial damage.

18 Mar 2022

Study shows small airways disease with the presence of air trapping is a long-lasting sequelae of SARS-CoV-2 infection

Researchers investigated whether small airway diseases are present following acute SARS-CoV-2 infection.

18 Mar 2022

Study shows BCG vaccination reduces SARS-CoV-2-induced lung inflammation in hamsters

Researchers tested the effectiveness of the BCG vaccine in SARS-CoV-2-infected Syrian hamsters.

18 Mar 2022

Excessive neuropeptide secretion in the lungs can lead to fluid buildup and poor oxygenation

COVID-19 has put a spotlight on the pulmonary and nervous systems, but there is still much to learn about how they interact. Researchers at University of California San Diego School of Medicine recently explored this relationship in the context of a childhood lung disease, but their findings may also apply to COVID-19 symptoms.

17 Mar 2022

Evaluating vesicular stomatitis virus-based COVID-19 vaccines against SARS-CoV-2 variants in hamsters

Researchers assessed the efficacy of vesicular stomatitis virus-based coronavirus disease 2019 vaccines in Syrian golden hamsters.

17 Mar 2022

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Researchers studied the immune responses in Syrian hamsters re-infected with SARS-CoV-2 Delta and B.1 variants three months after the primary infection.

17 Mar 2022

Inhalable ‘aerogel’ induces immune response against COVID-19 in the lungs of mice

An inhalable 'aerogel' loaded with DNA that encodes for the SARS-CoV-2 spike protein successfully induces an immune response against COVID-19 in the lungs of mice, according to new research conducted at Penn State.

16 Mar 2022

Toxin-producing yeast strains may damage the gut of patients with inflammatory bowel disease

Individual Candida albicans yeast strains in the human gut are as different from each other as the humans that carry them, and some C. albicans strains may damage the gut of patients with inflammatory bowel disease (IBD), according to a new study from researchers at Weill Cornell Medicine.

16 Mar 2022

The Future of Tuberculosis; An Interview with the Bill & Melinda Gates Medical Research Institute

We speak to Dr. Alemnew Dagnew from the Bill & Melinda Gates Medical Research Institute, about their tuberculosis vaccine study and the future of tuberculosis.

16 Mar 2022

Study reveals how to identify and avoid risks related to mitochondrial therapeutic interventions

Research carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has demonstrated that mixing mitochondrial DNAs (mtDNAs) of different origins can have damaging effects over the medium and long term.

16 Mar 2022

Researchers receive grant to find answers to taste loss in COVID patients

Up to 80% of individuals who've had COVID-19 report temporary or lasting changes in their sense of taste, and scientists are working to better understand the biological basis of why, including whether our taste buds are a direct virus target.

15 Mar 2022

Recovery of consciousness may take weeks for most COVID patients on respirators

Most patients with severe COVID who are put on ventilators regain consciousness after removal of respiratory support, but recovery may take weeks after the period of mechanical ventilation has ended, according to a new study by investigators at Weill Cornell Medicine, Columbia University Vagelos College of Physicians and Surgeons, Harvard Medical School, NewYork-Presbyterian and Massachusetts General Hospital.

15 Mar 2022

Small airways disease is a potential long-lasting effect of COVID-19, study says

Disease of the small airways in the lungs is a potential long-lasting effect of COVID-19, according to a new study published in the journal Radiology.

15 Mar 2022

Lungs News and Research

Oral version of remdesivir could extend its reach and benefits to COVID-19 patients

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

Antimalarial drugs are also effective at treating a pulmonary disease, study finds

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

IU researchers exploring new ways to treat seasonal or intermittent asthma

SARS-CoV-2 infection found to reduce fetal lung volume as assessed by MRI

Study evaluates COVID-19 vaccination with recombinant accessory protein-deficient SARS-CoV-2

Hypoxia-inducible factors and SARS-CoV-2 manifestations

Study shows small airways disease with the presence of air trapping is a long-lasting sequelae of SARS-CoV-2 infection

Study shows BCG vaccination reduces SARS-CoV-2-induced lung inflammation in hamsters

Excessive neuropeptide secretion in the lungs can lead to fluid buildup and poor oxygenation

Evaluating vesicular stomatitis virus-based COVID-19 vaccines against SARS-CoV-2 variants in hamsters

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Inhalable ‘aerogel’ induces immune response against COVID-19 in the lungs of mice

Toxin-producing yeast strains may damage the gut of patients with inflammatory bowel disease

The Future of Tuberculosis; An Interview with the Bill & Melinda Gates Medical Research Institute

Study reveals how to identify and avoid risks related to mitochondrial therapeutic interventions

Researchers receive grant to find answers to taste loss in COVID patients

Recovery of consciousness may take weeks for most COVID patients on respirators

Small airways disease is a potential long-lasting effect of COVID-19, study says

The ultimate guide to lung research tools and protocols eBook

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Evaluating new approaches for rare disease genomics

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