Microscopy News and Research

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What makes viruses infectious?

In this interview, News-Medical spoke to Professor Peter Stockley about his latest research that looked at what makes viruses infectious.

23 Feb 2021

Influenza A virus defective interfering particles against SARS-CoV-2

In the search for a broadly acting pan-specific antiviral, an interdisciplinary team from Germany tested the previously proposed (for antiviral treatment against Influenza A infections) - Influenza A virus (IAV) defective interfering particles (DIPs). The research is published online on the bioRxiv preprint server.

23 Feb 2021

Fooling the novel coronavirus with a fake handshake to inactivate the virus

Fool the novel coronavirus once and it can't cause infection of cells, new research suggests.

22 Feb 2021

Study reveals mechanism for translation of maternally inherited mitochondrial genome

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

22 Feb 2021

COVID-19 vaccine candidate shows potential against SARS-CoV-2 and potential future zoonotic coronaviruses

A new study sheds light on the threat posed by future zoonotic coronaviruses to make similar leaps across species barriers to infect human beings and cause other pandemics.

22 Feb 2021

3D microscopy analysis provides accurate recreation of human glioblastoma’s features

Researchers at the Institut de Neurociències obtained a highly accurate recreation of human glioblastoma’s features using a novel 3D microscopy analysis

19 Feb 2021

Chicken-derived antibody shows potent neutralizing capacity against SARS-CoV-2 in vitro

Researchers report on a Chicken-derived antibody against SARS-CoV-2, offering preliminary data on a potential therapeutic for COVID-19 warranting further research.

19 Feb 2021

Developing Biochemically Sensitive Membranes with Electrochemistry

In this interview, News-Medical Life Sciences talks to Lane Baker, Professor of Chemistry at Indiana University Bloomington about the role of electrochemistry in developing biochemically sensitive membranes as well the work ongoing at the Baker lab.

From Pittcon 19 Feb 2021

Understanding the dynamics of brain blood flow could hold key for treating neurologic conditions

While the human brain has over 400 miles of total vasculature, little is known about the tiny capillaries that make up much of this intricate labyrinth of blood vessels critical for delivering oxygenated blood and nutrients to billions of brain cells.

19 Feb 2021

Biophysicists show how cancer cells become fluidized and squeeze through tissues

Working with colleagues from Germany and the US, researchers at Leipzig University have achieved a breakthrough in research into how cancer cells spread.

18 Feb 2021

Researchers use high-resolution imaging to observe HIV infection process in the cell nucleus

Scientists at EMBL Heidelberg and at the Zentrum für Infektiologie at Heidelberg University Hospital have succeeded for the first time in imaging HIV during transport into the nucleus of an infected cell.

18 Feb 2021

A glycan controls how SARS-CoV-2’s spike protein opens, study finds

Using simulations, a team of researchers in the U.S. found that the glycan at position N343 of the SARS-CoV-2 spike protein’s receptor-binding domain (RBD) helps in its opening. A mechanism that aids its binding to the host cell receptor.

18 Feb 2021

Scientists reveal the structure of glutamate transporter in our cells

For the first time, researchers have found one of the most important molecular machines in our cells uses a ‘twisting elevator’ mechanism, solving a mystery of how it transports crucial chemical signals from one cell to another.

18 Feb 2021

3D microscopy sheds light on the body’s immune response to obesity

Researchers who focus on fat know that some adipose tissue is more prone to inflammation-related comorbidities than others, but the reasons why are not well understood.

18 Feb 2021

Scientists reveal the shape of glutamate transporter in human cells

A University of Sydney-led international team of scientists has revealed the shape of one of the most important molecular machines in our cells the glutamate transporter, helping to explain how our brain cells communicate with one another.

18 Feb 2021

New collaborative project to study the complex roles of lipids in health, disease

A University of Minnesota-Mayo Clinic partnership has joined with the Zooniverse citizen scientist platform and the Francis Crick Institute in London to leverage world-leading expertise in microscope imaging with the power of citizen science to study the relationship between structure and function in biology to better understand health and disease.

17 Feb 2021

Mice study finds altered brain connectivity after prolonged anesthesia

Prolonged anesthesia, also known as medically induced coma, is a life-saving procedure carried out across the globe on millions of patients in intensive medical care units every year.

17 Feb 2021

Blood-clotting protein linked with tumor pathogenesis of CNS B-cell lymphoma

In people with central nervous system (CNS) lymphoma, cancerous B cells--a type of white blood cell--accumulate to form tumors in the brain or spinal cord, often in close proximity to blood vessels.

17 Feb 2021

New N501Y SARS-CoV-2 mutations increase binding to host cell receptor

A team of researchers used several assays, atomic force microscopy, and simulations to determine that the N501Y mutation in the virus’s receptor-binding domain (RBD) increased the interaction of the virus with the angiotensin-converting enzyme 2 (ACE2) receptor.

17 Feb 2021

Kruppel-like factor 15 controls skeletal muscle fat uptake and utilization

Metabolic diseases, such as obesity and type 2 diabetes, have risen to epidemic proportions in the U.S. and occur in about 30 percent of the population. Skeletal muscle plays a prominent role in controlling the body's glucose levels, which is important for the development of metabolic diseases like diabetes.

16 Feb 2021

Microscopy News and Research

What makes viruses infectious?

Influenza A virus defective interfering particles against SARS-CoV-2

Fooling the novel coronavirus with a fake handshake to inactivate the virus

Study reveals mechanism for translation of maternally inherited mitochondrial genome

COVID-19 vaccine candidate shows potential against SARS-CoV-2 and potential future zoonotic coronaviruses

3D microscopy analysis provides accurate recreation of human glioblastoma’s features

Chicken-derived antibody shows potent neutralizing capacity against SARS-CoV-2 in vitro

Developing Biochemically Sensitive Membranes with Electrochemistry

Understanding the dynamics of brain blood flow could hold key for treating neurologic conditions

Biophysicists show how cancer cells become fluidized and squeeze through tissues

Researchers use high-resolution imaging to observe HIV infection process in the cell nucleus

A glycan controls how SARS-CoV-2’s spike protein opens, study finds

Scientists reveal the structure of glutamate transporter in our cells

3D microscopy sheds light on the body’s immune response to obesity

Scientists reveal the shape of glutamate transporter in human cells

New collaborative project to study the complex roles of lipids in health, disease

Mice study finds altered brain connectivity after prolonged anesthesia

Blood-clotting protein linked with tumor pathogenesis of CNS B-cell lymphoma

New N501Y SARS-CoV-2 mutations increase binding to host cell receptor

Kruppel-like factor 15 controls skeletal muscle fat uptake and utilization

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Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo