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Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Mosaic Therapeutics, an oncology therapeutics company dedicated to resolving cancer’s complexity to power new treatments for patients, today announced the close of its $28 million series A funding round.

From Mosaic Therapeutics 4 Apr 2023

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children's Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma Therapy (NANT) Consortium has shown that the targeted therapy lorlatinib is safe and effective in treating high-risk neuroblastoma.

4 Apr 2023

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Company developing targeted oncology therapies spun out of world-leading research at the Wellcome Sanger Institute, in collaboration with the Netherlands Cancer Institute.

From Mosaic Therapeutics 4 Apr 2023

Overcoming challenges in flavivirus vaccine development: Exploring modern vaccine types for Dengue, Zika, and beyond

Researchers discuss the challenges impeding the development of vaccines against flaviviruses.

4 Apr 2023

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Researchers discover a small molecule drug candidate that could provide immediate protection against infection with SARS-CoV-2.

4 Apr 2023

The intercommunication between the central nervous system and the digestive system and its contribution to mental health status

Researchers presented a comprehensive analysis of the correlation between gut microbiota and neurological as well as psychiatric disorders.

3 Apr 2023

Developing lipid nanoparticles to carry mRNA specifically to the pancreas

Therapeutics that use mRNA - like some of the COVID-19 vaccines - have enormous potential for the prevention and treatment of many diseases.

31 Mar 2023

New microfluidic device quickly and automatically predicts the effectiveness of cancer treatment

One of the great challenges in the fight against cancer is to design new technologies for a personalized treatment for each patient.

31 Mar 2023

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

A recent review published in Biochemical Pharmacology summarized the ongoing research, providing insights into pathophysiology and emerging drugs for Alzheimer’s disease (AD).

31 Mar 2023

New model can speed up the evaluation process for drugs used to combat cervical cancer

Researchers at Oregon State University have created a means of speeding up and improving the evaluation process for drugs used to combat cervical cancer.

31 Mar 2023

Catheter-based renal denervation provides a new concept for the treatment of hypertension

Hypertension significantly increases the risk of cardiovascular events and it is associated with high rates of disability and mortality.

30 Mar 2023

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

As part of the worldwide effort to facilitate a research and clinical pathway toward successful xenotransplantation - the transplantation of living cells, tissues and organs from one species to another - two Johns Hopkins Medicine surgeons, Kazuhiko Yamada, M.D., Ph.D., and Andrew Cameron, M.D., Ph.D., will receive a total of $21.4 million in funding over the next two years under two sponsored research agreements with biotechnology company United Therapeutics Corporation.

29 Mar 2023

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra, has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments against this blood cancer, the second most frequent hematological cancer and incurable in most cases.

29 Mar 2023

Preclinical News and Research

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Overcoming challenges in flavivirus vaccine development: Exploring modern vaccine types for Dengue, Zika, and beyond

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

The intercommunication between the central nervous system and the digestive system and its contribution to mental health status

Developing lipid nanoparticles to carry mRNA specifically to the pancreas

New microfluidic device quickly and automatically predicts the effectiveness of cancer treatment

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

New model can speed up the evaluation process for drugs used to combat cervical cancer

Catheter-based renal denervation provides a new concept for the treatment of hypertension

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

3D cell culture system tests how inhibiting fibroblast activities can help treat lung cancer

Improved brain mapping reveals subtle cognitive changes in older adults with preclinical Alzheimer's disease

What is the effect of prior BCG vaccination on the immunogenicity and efficacy of subsequent COVID-19 vaccination?

Targeting the STING pathway with a combination strategy promotes antitumor activity

Metformin may reduce the risk of osteoarthritis

Advancements in understanding and treating breast cancer

Antibodies produced by newly developed mRNA vaccines are transferred from pregnant rabbits to offspring

Event guide: 4th LNP Formulation & Process Development Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics