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One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

A new study by investigators from Mass General Brigham found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test - a phenomenon known as virologic rebound.

13 Nov 2023

Hormonal contraceptives taken by adolescents may affect risk assessment behavior

Hormonal contraceptives taken by adolescents may influence development of the brain in a way that alters the recognition of risks, a new study in rats suggests.

13 Nov 2023

Initial high-risk antibody profile for antiphospholipid syndrome tends to remain high in pediatric patients, study finds

A new study by Hospital for Special Surgery (HSS) investigators has found that an initial high-risk antibody profile for antiphospholipid syndrome (APS) tended to remain high in pediatric patients.

13 Nov 2023

Vitamin D supplementation may reduce future dementia risk, study suggests

Everyone knows that vitamin D is vital for healthy bones and a stronger immune system but could low levels be a major driver of Alzheimer’s and age-related cognitive decline?

13 Nov 2023

UK regulator approves a diabetes drug for weight management in obese and overweight patients

The Medicines and Healthcare products Regulatory Agency (MHRA) has today (8 November 2023) authorised via a national application route, a new indication for the diabetes medicine, Mounjaro (tirzepatide), for weight loss and weight management in adults aged 18 and over.

13 Nov 2023

Food allergies may be linked to increased cardiovascular death risk, study finds

Sensitivity to common food allergens such as dairy and peanuts could be an important and previously unappreciated cause of heart disease, new research suggests – and the increased risk for cardiovascular death includes people without obvious food allergies.

13 Nov 2023

Multi-ancestry study reveals 187 new genetic risk factors for prostate cancer

In a comprehensive multi-ancestry GWAS meta-analysis, researchers identified 451 risk variants for prostate cancer, including 187 new variants, demonstrating the utility of such studies across diverse populations. This analysis not only increased understanding of genetic risk factors but also differentiated between aggressive and non-aggressive prostate cancer types, underscoring the potential of genetic risk scoring in guiding screening and early detection strategies.

12 Nov 2023

UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

Autologous stem cell transplant shows promise for young patients with severe juvenile systemic sclerosis

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, shows that patients with refractory juvenile systemic sclerosis improved significantly on nearly all measures for two years following autologous stem cell transplant.

10 Nov 2023

Brazzein and monellin: Safe alternatives to sugar, new research confirms

Toxicity assessments of monellin and brazzein.

10 Nov 2023

Blooming health: Unfolding the petal-perfect virtues of edible flowers

A comprehensive review of the nutritional and therapeutic benefits of edible flowers highlights their role in health, food security, and environmental sustainability. This study provides insight into the nutritional content of flowers, their potential health benefits due to bioactive compounds, and innovative sustainable uses like phytoremediation and natural dyes.

9 Nov 2023

Laser hair removal reduces the risk of recurrence in patients with pilonidal disease

Laser epilation, commonly known as laser hair removal, reduced the risk of recurrence in patients with pilonidal disease, an inflammatory, painful, and sometimes chronic or recurring condition, according to research conducted by Peter C. Minneci, M.D., Chair of Surgery at Nemours Children's Health, Delaware Valley, and published in JAMA Surgery.

9 Nov 2023

Allen Discovery Center for Neuroimmune Interactions launched at Mount Sinai

The Paul G. Allen Frontiers Group, a division of the Allen Institute, today announced the launch of the Allen Discovery Center (ADC) for Neuroimmune Interactions at the Icahn School of Medicine at Mount Sinai.

9 Nov 2023

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation that leads to pain, joint damage, and disability, which affects approximately 18 million people worldwide.

8 Nov 2023

CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

New research at ACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus while maintaining a robust response to vaccines.

7 Nov 2023

Salivary gland abnormalities in primary Sjögren's become more severe over time, study shows

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, shows that ultrasound-detected salivary gland abnormalities in primary Sjögren's become more severe over time and that the slow-to-progress disease likely starts long before it is first detected.

7 Nov 2023

JAK inhibitors and tocilizumab elicit better response rates in VEXAS syndrome

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, found that JAK inhibitors (JAKi) and tocilizumab elicited better response rates in VEXAS syndrome compared to other targeted therapies.

7 Nov 2023

$Study finds doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis$

Study finds doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis

Researchers will present the first-ever study of fractures and calcium pyrophosphate deposition disease at ACR Convergence 2023, the American College of Rheumatology's annual meeting.

7 Nov 2023

New method could enhance the ability to detect and predict anaphylaxis during oral food challenges

Food allergies can quickly turn a casual meal into a life-threatening situation.

7 Nov 2023

PET scans of the heart identify people at risk for Parkinson's and Lewy body dementia

In a small study, researchers at the National Institutes of Health have found that positron emission tomography (PET) scans of the heart may identify people who will go on to develop Parkinson's disease or Lewy body dementia among those at-risk for these diseases.

7 Nov 2023

Skin News and Research

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

Hormonal contraceptives taken by adolescents may affect risk assessment behavior

Initial high-risk antibody profile for antiphospholipid syndrome tends to remain high in pediatric patients, study finds

Vitamin D supplementation may reduce future dementia risk, study suggests

UK regulator approves a diabetes drug for weight management in obese and overweight patients

Food allergies may be linked to increased cardiovascular death risk, study finds

Multi-ancestry study reveals 187 new genetic risk factors for prostate cancer

UCI researchers discover gene critical for muscle repair

Autologous stem cell transplant shows promise for young patients with severe juvenile systemic sclerosis

Brazzein and monellin: Safe alternatives to sugar, new research confirms

Blooming health: Unfolding the petal-perfect virtues of edible flowers

Laser hair removal reduces the risk of recurrence in patients with pilonidal disease

Allen Discovery Center for Neuroimmune Interactions launched at Mount Sinai

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

Salivary gland abnormalities in primary Sjögren's become more severe over time, study shows

JAK inhibitors and tocilizumab elicit better response rates in VEXAS syndrome

Study finds doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis

New method could enhance the ability to detect and predict anaphylaxis during oral food challenges

PET scans of the heart identify people at risk for Parkinson's and Lewy body dementia

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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