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Myocardial regeneration by intracoronary infusion in AMI (REGENT) randomized trial

REGENT is a multicenter, randomized trial for comparison of intracoronary infusion of bone marrow-derived unselected mononuclear cells (MNC) and selected CD34+CXCR4+ cells in 200 patients with acute myocardial infarction and reduced LVEF ¡Ü 40%.

2 Sep 2008

MorphoSys announces publication of first MOR103 data

MorphoSys AG announced today the publication of a first data package for its most advanced proprietary drug development program MOR103, a fully human HuCAL antibody directed against GM-CSF, in the journal "Molecular Immunology".

2 Sep 2008

Takeda and Affymax provide update for Hematide in chemotherapy-induced anemia

Takeda Pharmaceutical Company Limited and Affymax, Inc. today announced their agreement to suspend co-development of Hematide to treat chemotherapy-induced anemia and to focus all development efforts for Hematide on the treatment of chronic kidney disease related anemia.

28 Aug 2008

Potential new targets for antidepressants

The news about antidepressant medications over the past several years has been mixed. The bad news from large multicenter studies such as STAR*D is that current antidepressant medications are effective, but not as effective as one might hope. Thus, there is a significant need for new treatment mechanisms for depression. On that front, there has been mixed news as well.

27 Aug 2008

VioQuest Pharmaceuticals issued new U.S. patent for Lenocta

VioQuest Pharmaceuticals today announced that the United States Patent and Trademark Office has issued the first patent for the company's investigational product candidate Lenocta (sodium stibogluconate). U.S. Patent No. 7,416,723 entitled "Therapeutic compositions and methods useful in modulating protein tyrosine phosphatases," encompasses novel compositions including Lenocta for the treatment of cancer and a broad range of other diseases.

26 Aug 2008

New technique offers hope for stroke sufferers

If a stroke patient doesn't get treatment within approximately the first three hours of symptoms, there's not much doctors can do to limit damage to the brain.

25 Aug 2008

New vaccine to fight multiple influenza strains

A universal vaccine effective against several strains of influenza has passed its first phase of testing, according to Dr. Christine Turley of the University of Texas at Galveston.

21 Aug 2008

Lycopene molecules in tomatoes could help fight cancer

Turning up the heat on the red tomato during processing has the potential to give the popular garden staple added disease-fighting power, Ohio State University research suggests.

20 Aug 2008

Significant long-term benefit for low back pain revealed by major study

A major study led by a Southampton researcher has found significant evidence that the Alexander Technique can provide long-term benefit for people with chronic or recurrent low back pain.

20 Aug 2008

Alexander Technique shows long-term benefit for low back pain

A major study - one of the first of its kind - has found significant evidence that the Alexander Technique can provide long-term benefit for people suffering from chronic or recurrent low back pain. The study by researchers at the Universities of Bristol and Southampton is published today in the BMJ.

19 Aug 2008

New sickle cell unrelated transplant trial

Children's National Medical Center immunologist and blood and marrow transplant physician Naynesh Kamani, MD, will serve as the study co-chair for a new national clinical trial of unrelated donor marrow and umbilical cord blood transplants for severe sickle cell disease.

18 Aug 2008

URMC & NIH partner to expand, accelerate clinical research in neurological diseases

The University of Rochester Medical Center (URMC) and the National Institute of Neurological Disorders and Stroke are hosting a week-long training session designed to create a new generation of researchers with the specialized skills necessary to conduct clinical trials in neurological disorders.

14 Aug 2008

Cheap drug combo stops breast cancer in its tracks

A drug 'combo' of chemotherapy and a treatment for brittle bones has a dramatic effect on breast cancer according to researchers in the UK.

13 Aug 2008

Precisely targeted radiation therapy can control limited cancer spread

Precisely targeted radiation therapy can eradicate all evidence of disease in selected patients with cancer that has spread to only a few sites, suggests the first published report from an ongoing clinical trial.

12 Aug 2008

Medicinal cannabis effective for neuropathic pain in HIV

In a double-blind, placebo-controlled clinical trial to assess the impact of smoked medical cannabis, or marijuana, on the neuropathic pain associated with HIV, researchers at the University of California, San Diego School of Medicine found that reported pain relief was greater with cannabis than with a placebo.

6 Aug 2008

Revolutionary technique that could reduce lifelong drugs for transplant patients shows promising findings

Researchers have developed a ground-breaking procedure that could avoid the need for transplant patients to spend the rest of their lives taking a cocktail of drugs to stop their system from rejecting their new organ, according to a series of papers in the August issue of Transplant International.

5 Aug 2008

Bionor Immuno trials new innovative therapeutic immunization designed to help existing HIV and AIDS patients

Bionor Immuno today announced that it has advanced its efforts to develop the first HIV therapeutic immunization with the dosing of patients in a global Phase 2b clinical trial of the company's lead candidate (Vacc-4x).

4 Aug 2008

Immune system protein accurate predictor of survival in pediatric septic shock

About 4,000 children in the United States die every year from uncontrolled infections of the body known as septic shock, and researchers are pushing the boundaries of molecular science to find new therapies that can stem the condition. But a simple measure of an immune system protein within 24 hours of being admitted to the hospital for septic shock can predict survival in children, yielding a powerful tool for diagnostics and clinical trials of new septic shock therapies, according to a research team led by Cincinnati Children's Hospital Medical Center in the Aug. 1 American Journal of Respiratory and Critical Care Medicine.

4 Aug 2008

ShangRing - innovative circumcision device

With the recent endorsement by the World Health Organization (WHO) and scientists worldwide of adult male circumcision as an important strategy for HIV prevention, there is increased urgency to develop safe and cost-effective circumcision services. This is especially the case in Africa where HIV/AIDS continues to spread at an epidemic rate.

4 Aug 2008

Immunotherapy shows promise in high-risk pediatric sarcomas

Based on a pilot study in children with sarcoma, researchers at the National Institutes of Health (NIH) believe that immunotherapy could prove beneficial in treating high-risk forms of this cancer.

3 Aug 2008