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Study provides evidence that oral immunotherapy may be possible cure for peanut allergy

Allergy immunotherapy company Prota Therapeutics Pty Ltd is pleased to announce results from a follow up study of the probiotic and peanut immunotherapy (PPOIT) treatment which it has licensed from the Murdoch Childrens Research Institute, demonstrating long-lasting tolerance effects of treatment more than four years after the original study ended.

18 Aug 2017

FDA approves Besponsa – Pfizer’s new drug for rare form of acute lymphoblastic leukemia

The U.S. Food and Drug Administration (FDA) today approved Besponsa (inotuzumab ozogamicin) in the treatment of adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL) - a rare form of ALL.

17 Aug 2017

Peanut allergy successfully kept at bay with immune-based therapy

Australian researchers from the Murdoch Children’s Research Institute have come up with a latest study results showing that peanut allergy could be treated successfully with an immune-based therapy. This new therapy helped children allergic to peanuts eat these nuts with no reactions for up to four years. The study appeared this week in the journal Lancet Child & Adolescent Health.

17 Aug 2017

Researchers get closer to creating new blood test that can identify breast cancer brain metastasis

Houston Methodist cancer researchers are now closer to creating a blood test that can identify breast cancer patients who are at increased risk for developing brain metastasis, and also monitor disease progression and response to therapy in real time.

17 Aug 2017

$FDA approval provides new, targeted treatment option for adults with relapsed or refractory B-cell ALL$

FDA approval provides new, targeted treatment option for adults with relapsed or refractory B-cell ALL

The U.S. Food and Drug Administration today approved Besponsa (inotuzumab ozogamicin) for the treatment of adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).

17 Aug 2017

Women’s decision-making habits combined with values impact choice of breast cancer treatment

A new study finds that more than half of women with early stage breast cancer considered an aggressive type of surgery to remove both breasts.

17 Aug 2017

Artificial womb may provide avenue to improve outcomes for extremely preterm infants

An artificial womb has been successfully used to incubate healthy baby lambs for a period of one week, and researchers hope the technology will one day be able to do the same for extremely premature babies.

17 Aug 2017

Smoking linked to increased risk of aneurysm recurrence after endovascular treatment

In a new study, researchers report people who have experienced an aneurysm have another reason to quit smoking.

17 Aug 2017

Sanford Health launches solid tumor oncolytic virus clinical trial

Sanford Health is the first site in the United States to launch a clinical trial using a genetically-engineered virus that aims to destroy therapy-resistant tumors.

17 Aug 2017

Scientists discover novel therapeutic strategy to treat aggressive subgroup of lung cancer

Research conducted by a team of Norton Thoracic Institute scientists on a novel therapeutic avenue for an aggressive and difficult to treat subgroup of lung cancer was published in the August 15, 2017 issue of Cancer Research.

17 Aug 2017

Research highlights need for expert treatment to manage subarachnoid hemorrhages

Research led by the head of the Barrow Neurological Institute and published in the July 20, 2017 issue of The New England Journal of Medicine reveals that subarachnoid hemorrhages, which are caused by ruptured brain aneurysms, account for 5-10 percent of all strokes and are best managed by experienced and dedicated experts at high-volume centers with neurosurgeons, endovascular surgeons and stroke neurologists.

17 Aug 2017

Immunotherapy drug shows favorable safety profile in patients with advanced small cell lung cancer

The immunotherapy drug pembrolizumab has demonstrated a favorable safety profile and "promising durable clinical activity" in pretreated patients who exhibit high levels of the PD-L1 protein in advanced stages of small cell lung cancer (SCLC) – an aggressive form of the disease

16 Aug 2017

UC Irvine pharmacology researchers unearth potential roots of schizophrenia

An abundance of an amino acid called methionine, which is common in meat, cheese and beans, may provide new clues to the fetal brain development that can manifest in schizophrenia, University of California, Irvine pharmacology researchers report in the journal Molecular Psychiatry.

16 Aug 2017

Vaginal estrogens do not increase cancer, cardiovascular disease risk in post-menopausal women

Women who have gone through menopause and who have been using a vaginal form of estrogen therapy do not have a higher risk of cardiovascular disease and cancer than women who have not been using any type of estrogen.

16 Aug 2017

BU scientist wins $231,000 AHA award to improve cardiovascular therapies

Vijaya B. Kolachalama, PhD, assistant professor of medicine at Boston University School of Medicine, has received a Scientist Development grant from the American Heart Association.

16 Aug 2017

Blood biopsy helps identify targetable genetic alterations in patients with cancer of unknown primary

Using fragments of circulating tumor DNA in blood, University of California San Diego School of Medicine researchers were able to identify theoretically targetable genetic alterations in 66 percent of patients with cancer of unknown primary (CUP), a rare disease with seven to 12 cases per 100,000 people each year.

16 Aug 2017

Compounds produced by creosote bush exhibit anti-parasitic activity against pathogenic protozoa

Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego and the University of Colorado Anschutz Medical Campus have found that compounds produced by the creosote bush, a desert plant common to the Southwestern United States, exhibit potent anti-parasitic activity against the protozoa responsible for giardia infections and an amoeba that causes an often-lethal form of encephalitis.

16 Aug 2017

Older people treated with electroconvulsive therapy for depression may not get relief from insomnia

Older people receiving electroconvulsive therapy for their depression likely will need an additional treatment if insomnia is one of their symptoms, researchers report.

16 Aug 2017

ICP monitoring does not improve favorable outcome rate in patients with severe TBI, study shows

A new study has shown that use of intracranial pressure (ICP) monitoring in patients with severe traumatic brain injury (TBI) was associated with a significant decrease in mortality, but it did not improve the rate of favorable outcomes.

16 Aug 2017

Lab-grown miniature blood vessels mimic rare Hutchinson-Gilford Progeria Syndrome

Biomedical engineers have grown miniature human blood vessels that exhibit many of the symptoms and drug reactions associated with Hutchinson-Gilford Progeria Syndrome -- an extremely rare genetic disease that causes symptoms resembling accelerated aging in children.

16 Aug 2017

Therapy News and Research

Study provides evidence that oral immunotherapy may be possible cure for peanut allergy

FDA approves Besponsa – Pfizer’s new drug for rare form of acute lymphoblastic leukemia

Peanut allergy successfully kept at bay with immune-based therapy

Researchers get closer to creating new blood test that can identify breast cancer brain metastasis

FDA approval provides new, targeted treatment option for adults with relapsed or refractory B-cell ALL

Women’s decision-making habits combined with values impact choice of breast cancer treatment

Artificial womb may provide avenue to improve outcomes for extremely preterm infants

Smoking linked to increased risk of aneurysm recurrence after endovascular treatment

Sanford Health launches solid tumor oncolytic virus clinical trial

Scientists discover novel therapeutic strategy to treat aggressive subgroup of lung cancer

Research highlights need for expert treatment to manage subarachnoid hemorrhages

Immunotherapy drug shows favorable safety profile in patients with advanced small cell lung cancer

UC Irvine pharmacology researchers unearth potential roots of schizophrenia

Vaginal estrogens do not increase cancer, cardiovascular disease risk in post-menopausal women

BU scientist wins $231,000 AHA award to improve cardiovascular therapies

Blood biopsy helps identify targetable genetic alterations in patients with cancer of unknown primary

Compounds produced by creosote bush exhibit anti-parasitic activity against pathogenic protozoa

Older people treated with electroconvulsive therapy for depression may not get relief from insomnia

ICP monitoring does not improve favorable outcome rate in patients with severe TBI, study shows

Lab-grown miniature blood vessels mimic rare Hutchinson-Gilford Progeria Syndrome

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