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Discovered of gene mutations associated with hereditary neuralgic amyotrophy

In a significant advance toward understanding a perplexing and painful neurological disorder, an international team of researchers has discovered gene mutations associated with an inherited chronic pain and weakness syndrome known as hereditary neuralgic amyotrophy (also called HNA).

27 Sep 2005

Computer program helps explain how the same proteins can play different roles in a wide range of cellular processes

University of California, San Diego biochemists have developed a computer program that helps explain a long-standing mystery: how the same proteins can play different roles in a wide range of cellular processes, including those leading to immune responses and cancer.

27 Sep 2005

$Statin use associated with a 36 percent reduction in risk of fracture$

Statin use associated with a 36 percent reduction in risk of fracture

In a large study of elderly, predominately male veterans, statin use was associated with a 36 percent reduction in risk of fracture when compared with no lipid-lowering therapy, according to a study in the Archives of Internal Medicine

26 Sep 2005

Scientists identifiy new type of pain-sensing neuron in rats

We all know that if you put your hand over an open flame it's very painful. What you may not know is that, for some people, just lying under a blanket is painful as well. They have neuropathic pain--annoying, chronic pain that comes from a diseased nerve cell rather than a specific stimulus. Feeling phantom pain in a missing limb is another, more famous, example.

26 Sep 2005

Aquaporin-4 is the first specific molecule to be defined as a target for the autoimmune response in any form of MS

Researchers have identified a molecular suspect in a disorder similar to multiple sclerosis (MS) that attacks the optic nerve and spinal cord, according to a report presented at the 130th annual meeting of the American Neurological Association in San Diego. The protein, called aquaporin-4, is a channel protein that allows water to move in and out of cells.

26 Sep 2005

Lead exposures early in life combined with high blood pressure in working age adults may lead to diminishing cognitive abilities in later life

Exposure to lead in early childhood and adolescence may contribute to hypertension-related decline that can impair a person's cognitive abilities, according to a new study presented at the 2005 American Heart Association's High Blood Pressure Research meeting.

26 Sep 2005

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.

26 Sep 2005

Link between ambient air pollution and acute myocardial infarction, or heart attack

An article published in the Journal of Thrombosis and Haemostasis looks specifically at airborne particulate matter resulting mainly from the combustion of fuel, including coal and also from forest fires.

26 Sep 2005

Daylight savings changes may help extend the life and health of people's teeth and bones

Beginning in 2007, daylight savings time will be extended by almost a month. This additional amount of daylight may also help extend the life and health of people's teeth and bones. That's because vitamin D, also known as the "sunshine vitamin," is made by the body through casual and minimal sun exposure.

26 Sep 2005

HIV-infected macrophages in the brain continuously travel to part of the brain Alzheimer's disease often damages

Bacteria-eating cells that generally fight infection may cause dementia in HIV patients, University of Florida and University of California at San Francisco researchers have found.

26 Sep 2005

Definitive multiple sclerosis linkage screen

A cluster of genes on chromosome six is the only one that plays a significant role in multiple sclerosis (MS), according to the most complete genetic study to date in the disorder, presented at the 130th annual meeting of the American Neurological Association in San Diego.

22 Sep 2005

Significant death risk linked to airborne particles

Experts may be significantly underestimating air pollution's role in causing early death, according to a team of American and Canadian researchers, who studied two decades' worth of data on residents of the Los Angeles metro area.

20 Sep 2005

Periodontal disease develops much earlier than dentists and other health professionals thought

Periodontal disease -- a progressive, eventually painful and disruptive condition in which bacteria attack gums and the hidden roots of teeth -- develops much earlier than dentists and other health professionals thought, a major new study concludes.

20 Sep 2005

Researchers identify gene prevalent in the population that controls the clinical severity of asthma

The study by Bucala and his colleagues in Dublin, Ireland, included experiments in mice that are resistant to developing asthma because they lack the gene, and an examination of a human population in Dublin chosen for their similar ethnic and geographic identity.

20 Sep 2005

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Their findings that a chemical imbalance might underlie such damage could also lead to the development of anti-inflammatory drugs without the adverse side effects, the researchers said.

20 Sep 2005

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Researchers at The University of Texas M. D. Anderson Cancer Center and The University of Texas Health Science Center at Houston have found that human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke.

19 Sep 2005

Budesonide provides lasting relief for Crohn's disease patients

In a study published in The American Journal of Gastroenterology, researchers found that budesonide capsules are an effective treatment to prolong and maintain the period of remission of Crohn's Disease. Previous studies have demonstrated that budesonide is effective for inducing remission of Crohn's disease.

12 Sep 2005

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

A major finding by researchers at the La Jolla Institute for Allergy & Immunology (LIAI) has identified a previously unknown cellular mechanism that acts as an off switch for immune system function.

12 Sep 2005

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

A new treatment for patients with a type of bile duct cancer promises a greater chance at survival by combining radiation, chemotherapy and liver transplantation, Mayo Clinic physicians report in the September issue of the Annals of Surgery.

12 Sep 2005

Nuclear receptor proteins could change anti-inflammatory treatments

Several nuclear receptor proteins appear to overlap in their ability to exert anti-inflammatory effects, according to new research by scientists at the University of California, San Diego (UCSD).

12 Sep 2005

Inflammation News and Research

Discovered of gene mutations associated with hereditary neuralgic amyotrophy

Computer program helps explain how the same proteins can play different roles in a wide range of cellular processes

Statin use associated with a 36 percent reduction in risk of fracture

Scientists identifiy new type of pain-sensing neuron in rats

Aquaporin-4 is the first specific molecule to be defined as a target for the autoimmune response in any form of MS

Lead exposures early in life combined with high blood pressure in working age adults may lead to diminishing cognitive abilities in later life

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Link between ambient air pollution and acute myocardial infarction, or heart attack

Daylight savings changes may help extend the life and health of people's teeth and bones

HIV-infected macrophages in the brain continuously travel to part of the brain Alzheimer's disease often damages

Definitive multiple sclerosis linkage screen

Significant death risk linked to airborne particles

Periodontal disease develops much earlier than dentists and other health professionals thought

Researchers identify gene prevalent in the population that controls the clinical severity of asthma

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Budesonide provides lasting relief for Crohn's disease patients

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

Nuclear receptor proteins could change anti-inflammatory treatments

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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