Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Scleroderma is an independent determinant for coronary calcification, study suggests

A new study by researchers in Hong Kong suggests that systemic sclerosis is an independent determinant for moderate to severe coronary calcification or atherosclerosis.

11 May 2011

Research suggests systemic sclerosis is an independent risk factor for atherosclerosis

A new study by researchers in Hong Kong suggests that systemic sclerosis is an independent determinant for moderate to severe coronary calcification or atherosclerosis. Conventional cardiovascular risk factors such as age and hypertension predispose patients with systemic sclerosis to plaque build-up in the heart arteries similar to the general population. Details of this study are now available in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR).

10 May 2011

Charisela develops breakthrough adiponectin assay

Charisela Technologies, Inc., a manufacturer of advanced assays for flow cytometers, announced today that it has developed an adiponectin assay with major advantages over existing technologies, including the elimination of dilutions. Adiponectin (Acrp30), an adipocytokine, is important in many therapeutic arenas, including type 2 diabetes, obesity, atherosclerosis, and rheumatoid arthritis.

9 May 2011

Spherix effects 1-for-10 reverse stock split

Spherix Incorporated, an innovator in biotechnology for therapy in diabetes, metabolic syndrome and atherosclerosis; and providers of technical and regulatory consulting services to food, supplement, biotechnology and pharmaceutical companies, today announced that it has filed a Certificate of Amendment to its Certificate of Incorporation, as amended, to effect a 1-for-10 reverse stock split of its common stock that will become effective at end of business today.

7 May 2011

New project to explore European diet and healthy ageing

People are living longer. Rising living standards, improved lifestyle and better education, as well as greater access to quality healthcare services has meant that we can expect to reach 78 years of age, an increase of six years compared to the 1980s. However, data also shows that Europeans live to just over 60 years without being limited in their day-to-day activities by ill-health or disabilities.

6 May 2011

Esperion reports positive results from ETC-1002 Phase 1 study in dyslipidemia

Esperion Therapeutics, a privately held biotechnology company working to discover, develop and commercialize treatments for cardiovascular and metabolic diseases, today announced the results from a Phase 1 study and four preclinical studies for ETC-1002 at the Arteriosclerosis, Thrombosis and Vascular Biology 2011 Scientific Sessions in Chicago.

3 May 2011

BioInvent, ThromboGenics initiate TB-402 Phase IIb trial for VTE prophylaxis

ThromboGenics NV and co-development partner BioInvent International announce today that the first patient has been dosed in a Phase IIb trial with their novel long-acting anticoagulant TB-402 for the prophylaxis of venous thromboembolism after total hip surgery.

27 Apr 2011

Experts to present research on vascular biology and disease at ATVB meetings

Nearly 1,200 experts in cardiovascular medicine, vascular biology, endocrinology, hematology and other disciplines are expected to attend the American Heart Association's Arteriosclerosis, Thrombosis and Vascular Biology 2011 Scientific Sessions, April 28-30, in Chicago, Ill.

26 Apr 2011

VDF seeks nominations for PAD and venous disease research awards

The Vascular Disease Foundation is seeking nominations for research awards through its Peripheral Arterial Disease and Venous Disease Coalitions. Research awards recognize the important research relevant to the understanding and/or treatment of arterial and venous diseases.

25 Apr 2011

WSU researcher develops potential vaccine for Chlamydia

A Wayne State University School of Medicine researcher has developed a potential first ever vaccine for Chlamydia, the world's most prevalent sexually transmitted disease and the leading cause of new cases of blindness.

21 Apr 2011

Amylin's new metreleptin data in lipodystrophy to be presented at AACE meeting

Amylin Pharmaceuticals, Inc. today announced results from a new analysis of an ongoing, long-term research study of the investigational drug metreleptin, an analog of the human hormone leptin, for the treatment of lipodystrophy.

16 Apr 2011

Acute high-fat diets can protect against heart attack

Approximately one million Americans suffer a heart attack each year of which some 400,000 attacks are fatal. A key cause of heart attacks is atherosclerosis, a process in which cholesterol builds up in the arteries and impedes the ability of the blood to flow to our most vital organ.

15 Apr 2011

African-American adults with CVD may benefit from 'sunshine vitamin'

In recent years supplementation with Vitamin D has been shown to reduce the risk of cardiovascular disease in people who are deficient in the vitamin.

12 Apr 2011

Longitudinal displacement in carotid artery reflects both degree of atherosclerosis in artery and heart function

How your carotid artery moves can reveal your risk of a future heart attack, and it is now possible to study this vessel aspect in more detail thanks to a new technique which could eventually be used to identify patients with suspected coronary artery disease, reveals a thesis from the University of Gothenburg, Sweden.

12 Apr 2011

Positive interim results from PROLOR's hGH-CTP Phase II trial in growth hormone deficiency

PROLOR Biotech, Inc. today reported positive interim efficacy results from a Phase II clinical trial of its long-acting CTP-modified version of human growth hormone in growth hormone deficient adults.

11 Apr 2011

Experimental Biology 2011 to be held April 9-13 in Washington, D.C.

The meeting Experimental Biology 2011 (EB 2011) begins April 9 and runs through April 13 at the Walter E. Washington Convention Center in Washington, D.C.

8 Apr 2011

Cosmic radiation can increase risk of atherosclerosis in astronauts

Astronauts anticipate more trips to the moon and manned missions to Mars. But exposure to cosmic radiation outside the Earth's magnetic field could be detrimental to their arteries, according to a study by University of Alabama at Birmingham researchers published April 6, 2011, online in the journal Radiation Research.

8 Apr 2011

TBL1 levels may help identify obese persons at risk of developing fatty liver

Excess fat around the hips and belly may not really be compatible with current beauty ideals, but, to a certain degree, it is a normal, even vital energy store of our body. However, it is a different matter if the organism stores fat in organs such as the liver, pancreas or muscles. This is a clear sign of a metabolic disorder.

7 Apr 2011

Elevated BMI linked to high risk of obesity-related disorders in young adults

A large cohort study following 37,000 teenagers for 17 years found that an elevated, yet normal range Body Mass Index constitutes a substantial risk factor for obesity-related disorders in young adults.

7 Apr 2011

Vegans at increased risk of developing blood clots and atherosclerosis

People who follow a vegan lifestyle - strict vegetarians who try to eat no meat or animal products of any kind - may increase their risk of developing blood clots and atherosclerosis or "hardening of the arteries," which are conditions that can lead to heart attacks and stroke. That's the conclusion of a review of dozens of articles published on the biochemistry of vegetarianism during the past 30 years. The article appears in ACS' bi-weekly Journal of Agricultural and Food Chemistry.

7 Apr 2011