Cell Death News and Research

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Scientists highlight advances and uses of organoids in gastroenterology and hepatology

One of the most exciting advancements in stem cell research has been the development of organoid systems, which are organ-like three-dimensional structures that mimic their corresponding organ in vivo.

4 Jun 2019

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

For patients with operable non-small cell lung cancer, pre-surgical "neoadjuvant" treatment with an immune checkpoint inhibitor was well tolerated and, in many cases, caused significant tumor cell death in a large, multicenter clinical trial involving investigators at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and nine other research centers

31 May 2019

Viral study reveals new way to prevent kidney damage following organ transplant

While studying one of the smallest DNA viruses known, Sunnie Thompson, Ph.D., may have found a new way to help prevent kidney damage following organ transplant.

30 May 2019

Researchers discover unexpected survival mechanism of a subset of cancer cells

Embedded at the end of chromosomes are structures called "telomeres" that in normal cells become shorter as cells divide. As the shortening progresses it triggers cell proliferation arrest or death. Cancer cells adopt different strategies to overcome this control mechanism that keeps track of the number of times that a cell has divided.

28 May 2019

Coat of proteins makes viruses more infectious and facilitates plaque formation in Alzheimer's

New research from Stockholm University and Karolinska Institutet shows that viruses interact with proteins in the biological fluids of their host which results in a layer of proteins on the viral surface.

27 May 2019

New lithography method for producing complex tissues and organs

The production of artificial organs is a hot research topic. In the near future, artificial organs will compensate for the lack of organ donations and replace animal experiments.

23 May 2019

Scientists uncover unique set of genes that play a role in muscle cellular gene regulation

York University scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation which could lead to new therapeutic targets to prevent the spread of muscle cancer.

23 May 2019

Study explores how exposure to potential triggers can increase risk of type 1 diabetes

A new study has investigated how exposure to certain triggers can increase the risk of type 1 diabetes.

22 May 2019

Research uncovers potential breakthrough in the understanding of tumor dormancy

Scientists at VCU Massey Cancer Center may have uncovered a primary method through which cancer cells exist undetected in an organism and received more than $1 million to investigate the potential for novel therapeutics that target and destroy cells in a specific state of tumor dormancy.

22 May 2019

Small molecule drug could be an effective strategy to treat glioblastoma

A team of researchers have published in the International Journal of Oncology that RITA, a drug able to reactivate the oncosuppressor function of p53, could be an effective strategy to treat glioblastoma.

21 May 2019

Honey from strawberry trees stops cell proliferation in colon cancer lines

Spanish and Italian researchers have proven that when honey from strawberry trees, a product typical of Mediterranean areas, is added to colon cancer cells grown in the laboratory, cell proliferation is stopped.

21 May 2019

Marine natural compounds could be potential treatments for triple negative breast cancer

The oceans cover more than 70 percent of the earth's surface and provide a rich source of unique, bioactive natural products.

17 May 2019

Cellular conflict is crucial to development of healthy skin

Not all cells are destined for greatness. Deemed unfit to serve in the body, some are killed off during early development through a process called cell competition. This phenomenon has previously been documented in flies and is now turning out to occur in mammals as well.

16 May 2019

Researchers identify why lymphoma patients may become resistant to specific drug

With more targeted therapies being approved each year for cancer, the development of drug resistance to these agents is a growing concern.

16 May 2019

New drug could open up avenues for treatment of neonatal epilepsy

A new drug that inhibits neonatal seizures in rodent models could open up new avenues for the treatment of epilepsy in human newborns.

15 May 2019

Researchers identify new molecular mechanism causing rheumatoid arthritis

A collaborative study by research groups from the University of Cologne, VIB, Ghent University, the Βiomedical Sciences Research Center 'Alexander Fleming' in Athens and the University of Tokyo identified a new molecular mechanism causing rheumatoid arthritis.

14 May 2019

Researchers identify important signaling molecule in the biology of Hodgkin's lymphoma

Although classical Hodgkin's lymphoma is generally easily treatable today, many aspects of the disease still remain a mystery.

13 May 2019

Scientists discover how mutations in DNA can cause neurodegenerative disease

Scientists have discovered how mutations in DNA can cause neurodegenerative disease. The discovery is an important step towards better treatment to slow the progression or delay onset in a range of incurable diseases such as Huntington's and motor neurone disease - possibly through the use, in new ways, of existing anti-inflammatory drugs.

13 May 2019

Study uncovers Achilles' heel of lethal brain tumor

Glioblastoma is the most prevalent and also the most lethal type of brain tumor in adults, with no curative treatment currently available.

10 May 2019

Insights into parasitic yeast species could lead to new strategies for controlling yeast pathogens

Insights into the genes and proteins involved in the predatory behavior of a parasitic yeast species could lead to new strategies for controlling yeast pathogens, according to a study published May 9 in the open-access journal PLOS Pathogens by Jürgen Wendland of the Carlsberg Research Laboratory in Denmark and Vrije Universiteit Brussel in Belgium, and colleagues.