Metabolites News and Research

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Scientists uncover surprising molecular link in critical cellular growth pathway

A team of scientists led by Whitehead Institute has uncovered a surprising molecular link that connects how cells regulate growth with how they sense and make available the nutrients required for growth.

19 Oct 2017

Brazilian researchers find more significant cognitive deficits among early-onset cocaine users

People who begin using cocaine during adolescence display more significant cognitive deficits than people who begin using the drug in adulthood.

18 Oct 2017

Scientists develop new method for monitoring lipolysis by testing person's exhaled breath

Experts advise anyone looking to shed extra kilos to eat less and exercise more. One way is with endurance training, during which the body burns not only carbohydrates such as sugar, but also fat.

10 Oct 2017

Scientists discover how ZATT protein fixes DNA damage caused by cancer treatment

An international team led by scientists at the National Institutes of Health is the first to discover a new way that cells fix an important and dangerous type of DNA damage known as a DNA-protein cross-link.

6 Oct 2017

Good-guy bacteria may help individuals respond well to cancer immunotherapy

Individuals with certain types of bacteria in their gut may be more likely to respond well to cancer immunotherapy, researchers at the Harold C. Simmons Comprehensive Cancer Center found in a study of patients with metastatic melanoma.

5 Oct 2017

Scientists manipulate living cells to produce fluorinated bioplastics

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them.

4 Oct 2017

Black tea may promote weight loss and offer other health benefits

UCLA researchers have demonstrated for the first time that black tea may promote weight loss and other health benefits by changing bacteria in the gut. In a study of mice, the scientists showed that black tea alters energy metabolism in the liver by changing gut metabolites.

4 Oct 2017

Researchers produce fluorinated molecules in living cells

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them. American scientists have now genetically engineered a microbial host for organofluorine metabolism, allowing it to produce a fluoridated intermediate known as a diketide.

30 Sep 2017

Columbia University receives $9.6 million NIH grant for ME/CFS research center

The National Institutes of Health has awarded a five-year $9.6 million grant to the Center for Infection and Immunity at Columbia University's Mailman School of Public Health to create the Center for Solutions for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (CfS for ME/CFS), an inter-disciplinary, inter-institutional research group dedicated to understanding the biology of the disease in order to develop effective means to diagnose, treat and prevent it.

27 Sep 2017

Diet plus alcohol may play key role in liver injury development

A new study published in Alcohol and Alcoholism finds that mice bred to consume high amounts of alcohol, but controlled by diet, did not necessarily develop the most severe liver injuries, suggesting that diet may pay an important role in liver injury development.

25 Sep 2017

Probiotic bacteria can change intestinal flora of patients with colon cancer, study finds

Living lactic acid bacteria, probiotics, can change the intestinal flora of patients with cancer of the colon. These are the findings of a study published in the journal BMJ Open Gastroenterology.

25 Sep 2017

Metabolic changes after quitting could help explain how ill-effects of smoking may be reversible

Even after years of smoking, the body has a remarkable ability to repair itself. Now in a study appearing in ACS' Journal of Proteome Research, scientists report that certain metabolic changes occur soon after quitting, and these changes could help explain how some ill-effects of smoking might be reversible.

21 Sep 2017

Analytical Science in Precision Medicine

Pittcon is an analytical conference, so naturally my talk will be about analytical chemistry and how analytical chemistry will become increasingly important in delivering healthcare solutions, not only for rich people, but also, hopefully, for poor people across the world.

From Pittcon 19 Sep 2017

Research: The body's fat-metabolism causes detoxification of harmful substances from blood sugar

For several years, medical researchers, doctors, and dieticians have known that a low carbohydrate diet and plentiful fat can prevent a range of lifestyle and age-related diseases and thus promote healthy aging. But researchers from around the world have not been able to explain why this is the case.

18 Sep 2017

Penn State investigator receives $7.3 million grant for research on cellular protein

A faculty member in Penn State's College of Agricultural Sciences has received a $7.3 million grant for innovative research on a cellular protein that could be a target for enhancing immune function in response to a variety of diseases and environmental toxins.

15 Sep 2017

Probiotics may become new preventative or therapeutic strategy for IBD-related colon cancer

In an innovative approach to colorectal cancer (CRC) prevention and treatment, scientists are studying ways to replace missing metabolites in patients prone to gut inflammation and CRC.

14 Sep 2017

Researchers find unique genetic mutation in 74-year-old man with Parkinson's disease

Mutations in the human genome may be responsible for many diseases. In the case of Parkinson's disease (PD), five locations have been the subject of recent attention. Variants of one of these locations, ACMSD (aminocarboxymuconate semialdehyde decarboxylase), may be implicated in PD, but until now, no mutations in ACMSD have been found in any PD patients.

14 Sep 2017

Phthalate levels in expectant fathers influence sperm epigenetics, study suggests

Early results from a larger, ongoing study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst suggest that phthalate levels in expectant fathers have an effect on couples' reproductive success via epigenetic modifications of sperm DNA.

12 Sep 2017

New device detects cancerous tissue during surgery within seconds

Researchers from the University of Texas at Austin have invented a pen-like, handheld device that can identify cancerous tissue in around 10 seconds during surgery, offering hope that procedures to remove cancer could be made quicker, more precise and safer.

7 Sep 2017

Mild pain killer blocks action of key protein required for hearing

A Rice University study has found that the aspirin-like drug diflunisal blocks the action of prestin, a key protein that is required for hearing.

5 Sep 2017