Clinical Trial News and Research

RSS

Re-engineered human T cells effectively target and kill cancerous B cells

Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia (ALL), according to researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).

18 Sep 2007

Sanofi Pasteur's new H5N1 vaccine shows promise

Sanofi pasteur, the vaccines division of sanofi-aventis Group, has announced data showing that its new investigational H5N1 pandemic influenza vaccine containing a proprietary adjuvant achieved a high immune response at the lowest dose of H5N1 antigen reported to date.

18 Sep 2007

Circulating fats kill transplanted pancreas cells

New findings by UT Southwestern Medical Center researchers show that a byproduct of cholesterol metabolism interferes with the beneficial effects estrogen has on the cardiovascular system, providing a better understanding of the interplay between cholesterol and estrogen in heart disease.

18 Sep 2007

Digibind offers new hopes for pre-eclampsia cure

Researchers at the University of Texas Medical Branch at Galveston are trying to determine whether a drug already available to heart patients can also be used to delay delivery in expectant mothers with severe preeclampsia.

17 Sep 2007

Evista (raloxifene hydrochloride) approved for breast cancer

The U.S. Food and Drug Administration today approved Evista (raloxifene hydrochloride) for reducing the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer.

17 Sep 2007

Byproduct of cholesterol metabolism blocks heart health benefits of estrogen

17 Sep 2007

Byproduct of cholesterol interferes with the beneficial effects of estrogen on the heart

A new study possibly offers a biological reason why hormone replacement therapy (HRT) fails to protect some postmenopausal women from heart disease.

17 Sep 2007

IMPACT: Increasing clinical trial participation

Before a new treatment for a disease like cancer becomes available, physician-researchers must recruit hundreds or thousands of patients to participate in clinical research trials.

14 Sep 2007

Phase 3 study on novel oral direct thrombin inhibitor

Boehringer Ingelheim has announced that the September 15 issue of The Lancet will publish results from the RE-NOVATE study, which investigated dabigatran etexilate as a potential therapy for patients undergoing total hip replacement surgery.

13 Sep 2007

Gallbladder removed through vagina

Surgeons at the University of California, San Diego Medical Center have performed the first clinical trial surgery in the Southwest to evaluate the safety and effectiveness of performing abdominal procedures through the body's natural openings, virtually eliminating scarring.

From Evident Corporation - Life Sciences 13 Sep 2007

Vibrating catheters break through clogged arteries

A new vibrating catheter breaks through clogged arteries like a jackhammer, obliterating total blockages in patients with dangerous chronic total occlusions (CTOs).

13 Sep 2007

GlaxoSmithKline responds to Journal of the American Medical Association articles

GlaxoSmithKline believes that conclusions drawn from the most recent meta-analyses published by Drs. Nissen et. al. and Furberg et. al. in the Journal of the American Medical Association do not confirm a difference in the safety profile of Avandia (rosiglitazone) and Actos (pioglitazone).

12 Sep 2007

Generic prostate drug finasteride helps find high-risk cancers early

Men now have another good reason to consider taking finasteride, a well-known generic drug that shrinks an enlarged prostate and reduces the risk of getting prostate cancer by 25 percent.

12 Sep 2007

Customized virus kills brain tumor stem cells that drive lethal cancer

A tailored virus destroys brain tumor stem cells that resist other therapies and cause lethal re-growth of cancer after surgery, a research team led by scientists at the University of Texas M. D. Anderson Cancer Center reports in the Sept. 18 edition of the Journal of the National Cancer Institute.

12 Sep 2007

Link between nicotine and atherosclerosis

It's well known that smoking cigarettes increases risk for a host of serious health problems from cancer to heart disease. Now a new study from Weill Cornell Medical College in New York City looks at how they do their dirty work by contributing to atherosclerosis, or hardening of the arteries. The evidence points to nicotine, the addictive chemical in cigarettes.

11 Sep 2007