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Oglufanide disodium in new hepatitis C trial

Physicians at Southern Health have started a phase IIa clinical trial designed to test the efficacy of a new strategy for defeating hepatitis C viral infection, one of the toughest infectious diseases in the modern world.

26 Aug 2007

Study looks at salsalate for type 2 diabetes

The University of Illinois at Chicago is one of 16 sites in the United States taking part in the first large-scale study to test a promising approach to lowering blood glucose levels in adults with type 2 diabetes.

24 Aug 2007

Reported failure of vitamin E to prevent heart attacks may be due to underdosing

The findings, published early online in Free Radical Biology and Medicine, suggest that these earlier studies all had a fundamental flaw the doses used werent high enough to have a significant antioxidant effect.

24 Aug 2007

Study looks at large burns

Large burns can trigger cardiac problems and enhanced inflammatory and hypermetabolic responses in patients, a study in the online open access journal Critical Care suggests.

24 Aug 2007

Surgical options for severe intra-abdominal inflammation

Performing a repeat surgery for patients with peritonitis (severe intra-abdominal inflammation or infection) only when clinical improvement is lacking may have some advantages compared with having the repeat procedure routinely scheduled after the operation, according to a study in the August 22/29 issue of JAMA.

22 Aug 2007

Gastric banding clinical trial for adolescents

Millions of adults have turned to surgery when diet and exercise don't work. Now, with childhood obesity sharply on the rise, researchers are exploring whether surgery may be a viable option for teens.

22 Aug 2007

Pharmion and MethylGene announce orphan drug designation for treatment of Hodgkin's lymphoma

Pharmion Corporation, along with its collaborator MethylGene Inc., today announced that the U.S. Food and Drug Administration (FDA) has designated the Companies' histone deacetylase (HDAC) inhibitor, MGCD0103, as an Orphan Drug for the treatment of Hodgkin's lymphoma in the United States.

21 Aug 2007

Breakthrough pain medication

Cancer patients frequently experience two types of pain: persistent and breakthrough.

17 Aug 2007

FDA approves updated labeling for Warfarin (Coumadin)

The U.S. Food and Drug Administration has announced the approval of updated labeling for the widely used blood-thinning drug, Coumadin, to explain that people's genetic makeup may influence how they respond to the drug.

17 Aug 2007

Red meat and colon cancer recurrence

Colon cancer patients who eat a diet high in red meat, fatty products, refined grains, and desserts a so-called Western diet may be increasing their chance of disease relapse and early death, report researchers at Dana-Farber Cancer Institute.

16 Aug 2007

Diabetes increases risk of death for patients with acute coronary syndromes

Individuals with diabetes and acute coronary syndromes (ACS) such as a heart attack or unstable angina have an increased risk of death at 30 days and one year after ACS, compared with ACS patients without diabetes, according to a study in the August 15 issue of JAMA .

16 Aug 2007

Killer T cell treatment shows promise against cancers in transplant patients

Blood cell donations could be used to treat transplant patients with a particular form of cancer, according to a Cancer Research UK study reported in the journal Blood.

15 Aug 2007

New drug targets for multiple myeloma

Research investigators have identified molecular changes in multiple myeloma cells that activate an important biological pathway associated with cell growth and survival, thereby revealing potential new targets for drugs to treat this cancer.

13 Aug 2007

Alarm over death in clinical trial for arthritis therapy

The death of a woman taking part in a clinical trial for an arthritis therapy has set alarm bells ringing in the United States.

12 Aug 2007

Statins do not protect against prostate cancer

A large community-based study refutes previous findings that statins , a top-selling drug class, worldwide -- might cut one's risk of developing prostate cancer by reducing production of the male hormones that fuel cancer growth.

11 Aug 2007

Prophylaxis effective at preventing joint bleeds and preserving joint function and structure in young boys with hemophilia A

According to a new landmark study published in The New England Journal of Medicine, infusions of clotting factor VIII used preventively can significantly reduce the risk of developing joint damage associated with joint bleeding in young children with hemophilia A.

9 Aug 2007

Court says terminally ill have no right to experimental drugs

An appeals court in the United States has ruled that terminally ill patients do not have a constitutional right to experimental drugs not approved by regulators.

8 Aug 2007

Hypertension in the very elderly trial stopped

An international trial looking at the benefits of giving blood-pressure lowering medication to elderly patients has stopped early, after researchers observed significant reductions in overall mortality in those receiving treatment.

7 Aug 2007

Inhaled nitric oxide safe for very premature infants

A nationwide study led by researchers at UCSF provides evidence that inhaled nitric oxide is safe and effective for the prevention of the most common type of long-term lung disease of very premature infants.

7 Aug 2007

FDA approves maraviroc, an antiretroviral drug for use in adult HIV patients.

The U.S. Food and Drug Administration (FDA) has approved maraviroc, an antiretroviral drug for use in adult HIV patients. Maraviroc, sold under the trade name Selzentry, is the first in a new class of drugs designed to slow the advancement of HIV and received priority review by the FDA.

7 Aug 2007