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Implantable artificial lung

The University of Michigan Medical School laboratory working to develop an implantable artificial lung that can serve as a bridge to lung transplantation is entering the home stretch.

6 Aug 2007

GlaxoSmithKline receives bulk H5N1 antigen order for the US national stockpile

GlaxoSmithKline has announced that HHS has placed another order to purchase bulk H5N1 antigen for the US national stockpile of pre-pandemic vaccines.

6 Aug 2007

Electricity - a new weapon for stalling the progression of cancer

Low-intensity electric fields can disrupt the division of cancer cells and slow the growth of brain tumors, suggest laboratory experiments and a small human trial, raising hopes that electric fields will become a new weapon for stalling the progression of cancer.

3 Aug 2007

Gene variation makes people with depression more likely to respond to the medication citalopram

A variation in a gene called GRIK4 appears to make people with depression more likely to respond to the medication citalopram (Celexa) than are people without the variation, a study by the National Institute of Mental Health (NIMH), part of the National Institutes of Health, has found.

3 Aug 2007

Genta and Emisphere Technologies file investigational new drug exemption

Genta Inc. and Emisphere Technologies, Inc. have jointly announced the submission of an Investigational New Drug Exemption (IND) to the Endocrinologic and Metabolic Drugs Division of the U.S. Food and Drug Administration (FDA) for a new drug known as G4544.

2 Aug 2007

Novavax begins human clinical testing of novel pandemic flu vaccine

Novavax has announced that it has begun vaccinating healthy volunteers in the first human clinical trial of its virus-like particle ("VLP") based pandemic influenza vaccine.

1 Aug 2007

Active management of risk in pregnancy lowers Cesarean rates

At a time when national rates of cesarean delivery have climbed above 30%, a four-year study of patients receiving an alternative method of obstetric care experienced a significantly lower rate of cesarean births, according to a study published in the current issue of the Annals of Family Medicine .

1 Aug 2007

New TB vaccine could save over a million lives

Initial trials of a new tuberculosis (TB) vaccine mean the drug will now progress to phase II trials.

31 Jul 2007

New oral contraceptive means 365 period free days a year

Women in the United States can now access the first low-dose combination contraceptive pill which stops their periods.

31 Jul 2007

Takeda responds to FDA recommendation on Actos

Following a joint meeting today of the U.S. Food and Drug Administration (FDA) Endocrinologic and Metabolic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee, Takeda Global Research & Development (TGRD) underscores its position that ACTOS(R) (pioglitazone HCl) offers a proven safety profile regarding the risk of cardiovascular disease.

30 Jul 2007

Europe approves MIRCERA to treat anaemia

Roche has announced that the European Commission has approved its innovative drug MIRCERA to treat anaemia associated with chronic kidney disease (CKD).

27 Jul 2007

FDA statement on gene therapy trial

On July 24, 2007 the U.S. Food and Drug Administration (FDA) was informed by Targeted Genetics Corporation of Seattle about the death of a patient who received an investigational gene therapy product in a clinical trial for the treatment of active inflammatory arthritis.

27 Jul 2007

WHO announces China and India join clinical trial registry platform

The World Health Organisation (WHO) has announced the expansion of its clinical trial registry platform to include trial registers from China and India.

26 Jul 2007

The future of Alzheimer's disease research

Imagine the day when a routine visit to the family doctor includes a simple blood test to predict the risk for developing Alzheimer's disease (AD).

26 Jul 2007

Children with HIV early antiretroviral therapy study

Hundreds of thousands of babies around the world are born each year with HIV--more than half a million in 2006 alone.

26 Jul 2007

$Hip protectors do not reduce risk of hip fracture for nursing home residents$

Hip protectors do not reduce risk of hip fracture for nursing home residents

Use of an energy-absorbing hip protector did not provide a protective effect against hip fracture for nursing home residents, adding to increasing evidence that hip protectors, as currently designed, are not effective for preventing hip fractures, according to a study in the July 25 issue of JAMA.

25 Jul 2007

FDA advisory committee recommends that FDA wait for overall survival results from Satraplatin phase 3 trial

GPC Biotech AG has announced that the Oncologic Drugs Advisory Committee (ODAC) for the U.S. Food and Drug Administration (FDA) recommended (12-0) that the FDA should wait for the final survival analysis of the SPARC trial before deciding whether the satraplatin application is approvable for the treatment of hormone-refractory prostate cancer patients whose prior chemotherapy has failed.

25 Jul 2007