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Abiraterone reduces levels of prostate specific antigen

For prostate cancer patients whose tumors have continued to grow despite medical or surgical castration, a new drug candidate that inhibits production of male hormones anywhere in the body is showing promise in early trials.

9 Jul 2007

Colesevelam HCl hits diabetes with one-two punch

Patients with type 2 diabetes may soon be able to control their glucose and their cholesterol levels with a single drug, according to a study led by Vivian A.

9 Jul 2007

Modified herpes simplex virus shows promise in early clinical trial

A virus that has been specifically designed by scientists to be safe to normal tissue but deadly to cancer is showing early promise in a preliminary study, researchers said at the ESMO Conference Lugano (ECLU), Switzerland.

9 Jul 2007

Lung cancer patients taking Tarceva who develop a rash fair better

The appearance of a rash in cancer patients treated with erlotinib (Tarceva) is strongly associated with longer survival, according to researchers from the drug's developer, OSI Pharmaceuticals, Inc.

4 Jul 2007

A view on new drugs for macular degeneration

Restricting use of drugs for macular degeneration to patients who have already gone blind in one eye is "unacceptable" concludes the July issue of Drug and Therapeutics Bulletin (DTB).

4 Jul 2007

Study to look at effect of using nicotine patches during pregnancy

1050 pregnant women are being recruited for the most extensive trial of its kind to establish the effect of using nicotine patches during pregnancy.

4 Jul 2007

Skin rash actually signifies better outcomes for pancreatic and lung cancer patients

The appearance of a rash in cancer patients treated with erlotinib (Tarceva) is strongly associated with longer survival, according to researchers from the drug's developer, OSI Pharmaceuticals, Inc.

3 Jul 2007

Patient choice and treatment alternatives for arthritis

Patients with osteoarthritis (OA) and rheumatoid arthritis (RA) face different treatment options and determining which ones to try can be confusing.

29 Jun 2007

Biovest announces interim blinded data of fast-tracked pivotal phase 3 clinical trial of BiovaxID

Biovest International announced on June 27, 2007 blinded interim data from the start of its fast-tracked pivotal Phase 3 clinical trial of BiovaxID for Non-Hodgkin's lymphoma (NHL) from September 2000 through June 2006.

29 Jun 2007

Trial shows CERVARIX cervical cancer candidate vaccine effective

Results from an interim analysis of a Phase III study show that CERVARIX, the GlaxoSmithKline (GSK) cervical cancer candidate vaccine, provides up to 100 percent protection against advanced precancerous lesions caused by the most common types of human papillomavirus, types 16 and 18.

28 Jun 2007

Family-based weight management program cuts diabetes risk, improves BMI in overweight children

Children who participated in a family-based weight management program designed for inner-city minority children had better outcomes regarding weight gain, body fat, body mass index (BMI) and insulin sensitivity compared to children who received traditional weight counseling in a clinic, according to a study in the June 27 issue of JAMA: The Journal of the American Medical Association, a theme issue on chronic diseases of children.

27 Jun 2007

Substance from lapacho tree could lead to new lung-cancer treatment

Researchers at UT Southwestern Medical Center have determined how a substance derived from the bark of the South American lapacho tree kills certain kinds of cancer cells, findings that also suggest a novel treatment for the most common type of lung cancer.

26 Jun 2007

Omega-3 polyunsaturated fatty acids protect against retinopathy

Omega-3 polyunsaturated fatty acids protect against the development and progression of retinopathy, a deterioration of the retina, in mice.

26 Jun 2007

Basically eating fish may protect against type of blindness

Increasing intake of the omega-3 fatty acids DHA and EPA, found in popular fish-oil supplements, may protect against blindness resulting from abnormal blood vessel growth in the eye, according to a study published online by the journal Nature Medicine on June 24.

26 Jun 2007

Worldwide clinical trial of cardiac resynchronization therapy

The University of Zurich has announced an investigator initiated large-scale prospective randomized controlled clinical trial to assess the clinical impact of Cardiac Resynchronization Therapy (CRT) in heart failure patients.

23 Jun 2007

Stem cells to repair damaged heart muscle

In the first trial of its kind in the world, 60 patients who have recently suffered a major heart attack will be injected with selected stem cells from their own bone marrow during routine coronary bypass surgery.

23 Jun 2007

Polyethylene laxative safe for patients suffering from chronic constipation

A clinical trial including 50 medical centers and 304 patients has confirmed that polyethylene (PEG) laxative is safe for patients suffering from chronic constipation.

23 Jun 2007

Experimental Alzheimer's drug begins clinical trials

A drug based on the design of a Purdue University researcher to treat Alzheimer's disease began the first phase of human clinical trials this week.

23 Jun 2007

Link between levels of urate in the blood and risk of Parkinson's disease

In a new, large-scale, prospective study exploring the link between levels of urate in the blood and risk of Parkinson's disease, researchers from the Harvard School of Public Health (HSPH) have found that high levels of urate are strongly associated with a reduced risk of the disease.

23 Jun 2007

New way to increase stem cells in blood

Researchers at Children's Hospital Boston report finding a new way to increase stem cells in blood, suggesting a possible treatment to help patients who undergo chemotherapy or bone marrow transplant for leukemia and other cancers recover their immune function more quickly.

23 Jun 2007